Abstract：
BACKGROUND:Connective tissue nevi (CTN) may be isolated, either sporadic or hereditary, or syndromic as in the Buschke-Ollendorff syndrome. Few publications have addressed the variable clinical and histopathologic expression of these benign hamartomas. OBJECTIVE:We sought to characterize the clinical and histopathologic features of CTN and to highlight a spectrum of clinical disease. METHODS:We carried out a retrospective study of cases selected after strict clinical and histopathologic confirmation of the diagnosis. RESULTS:A total of 33 patients with CTN were included. The average age of onset was 2 years. Three clinical forms were distinguished: type A with lesions at a single site, with one case presenting as an ulcerated infiltrated plaque; type B with two or more sites of involvement; and type C with unusually severe infiltration with functional impairment of a limb. Histopathologic examination of lesional biopsy specimens showed 10 collagenomas, one elastoma, 18 mixed CTN, and an increased number of fibroblasts in 4 cases. No correlation between clinical type and histopathologic findings was observed. LIMITATION:This was a descriptive case series. CONCLUSIONS:CTN comprise a clinical spectrum ranging from isolated papules to unusually severe aggressive plaques with monomelic involvement. The histopathologic features are heterogeneous and include a newly described variant, which we name "cellular CTN" because of the increased number of fibroblasts.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Saussine A,Marrou K,Delanoé P,Bodak N,Hamel D,Picard A,Sassolas B,de Prost Y,Lemerrer M,Fraitag S,Bodemer Cdoi
10.1016/j.jaad.2011.08.008subject
Has Abstractpub_date
2012-08-01 00:00:00pages
233-9issue
2eissn
0190-9622issn
1097-6787pii
S0190-9622(11)00910-8journal_volume
67pub_type
杂志文章abstract：BACKGROUND:Onychomycosis, a fungal infection of the nail bed, is responsible for up to 50% of nail disorders. Although several surveys have been conducted in different parts of the world, there have been no multicenter epidemiologic surveys of onychomycosis in North America. OBJECTIVE:A 12-center study was undertaken ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,多中心研究
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Journal of the American Academy of Dermatology
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abstract：BACKGROUND:Psoriasis's effect on diabetes onset is well documented, but its effect on course of diabetes is poorly understood. OBJECTIVE:We sought to compare risks of developing microvascular and macrovascular complications between diabetic patients with and without psoriasis. METHODS:Adults with 2 or more diabetes d...
journal_title：Journal of the American Academy of Dermatology
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abstract：:Cutaneous fungal infections are a major source of morbidity in HIV-infected patients, and their management poses special challenges. Superficial mycoses, such as tinea pedis, tinea cruris, tinea corporis, and onychomycosis, are no more common in HIV-infected patients than in the HIV-negative population but are of grea...
journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
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abstract：:We hereby report a case presenting a rare form of secondary syphilis with an unusual nodular eruption accompanied by pruritus and generalized lymphadenopathy, bearing a striking resemblance to lymphoma. The histologic picture was also misleading and was compatible with lymphocytoma cutis. The diagnosis was eventually ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(87)70280-1
更新日期：1987-11-01 00:00:00
abstract：BACKGROUND:Many factors influence anxiety and satisfaction of patients undergoing Mohs micrographic surgery (MMS). OBJECTIVE:We sought to determine the effect of a preoperative educational telephone call on anxiety and satisfaction for patients undergoing same-day office consultation and MMS. METHODS:Patients with sk...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jaad.2016.09.027
更新日期：2017-03-01 00:00:00
