The clinical relevance of oral contraceptive pill-induced plasma lipid changes: facts and fiction.

Abstract:

:The changes in plasma lipids induced by the use of oral contraceptive pills have been shown in several studies to remain within normal physiologic limits. These changes are then probably without any clinical relevance because there is no evidence in the huge volume of oral contraceptive and cardiovascular literature that the use of oral contraceptives promotes or retards the development of atherosclerotic disease. What may appear to be favorable changes in the lipid profile attributed to oral contraceptive use may actually be associated with unfavorable changes in other parameters, such as the balance of clotting and fibrinolytic factors. A well-balanced, low-dose oral contraceptive formulation should alter any of the cardiovascular risk indicators as little as possible in either a supposedly positive or negative direction.

journal_name

Am J Obstet Gynecol

authors

Hoppe G

doi

10.1016/0002-9378(90)90588-x

subject

Has Abstract

pub_date

1990-07-01 00:00:00

pages

388-91

issue

1 Pt 2

eissn

0002-9378

issn

1097-6868

pii

0002-9378(90)90588-X

journal_volume

163

pub_type

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