Radiofrequency ablation of human fetal sacrococcygeal teratoma.

Abstract:

OBJECTIVE:Fetuses with solid, highly vascularized sacrococcygeal teratomas can die as a result of the vascular steal syndrome. This is the first report in which a percutaneous technique, radiofrequency ablation, was used to interrupt blood flow to a sacrococcygeal teratoma in 4 human fetuses. STUDY DESIGN:A radiofrequency ablation probe was percutaneously inserted into the fetal tumor under ultrasonographic guidance. In 2 fetuses a significant portion of the tumor mass was ablated, whereas in the other 2 fetuses only the major feeding vessels were targeted. RESULTS:Two infants were delivered at 28 and 31 weeks' gestation, respectively, and are doing well. In 2 other cases hemorrhage into the tumor led to an unfavorable fetal outcome. CONCLUSION:Ablation of a majority of the tumor tissue in sacrococcygeal teratoma is not necessary and proved fatal in two instances. Targeted ablation of the feeding tumor vessels diminishes blood flow sufficiently to reverse high-output fetal heart failure.

journal_name

Am J Obstet Gynecol

authors

Paek BW,Jennings RW,Harrison MR,Filly RA,Tacy TA,Farmer DL,Albanese CT

doi

10.1067/mob.2001.110446

subject

Has Abstract

pub_date

2001-02-01 00:00:00

pages

503-7

issue

3

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(01)03371-3

journal_volume

184

pub_type

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