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Heterogeneity and expression of the Plasmodium falciparum 5.8S ribosomal RNA genes.

Abstract：

:The number and expression of some of the large ribosomal RNA (rRNA) gene classes present in the human malaria parasite Plasmodium falciparum was determined. Southern blot analyses, using the 5.8S rRNA coding region as a marker, indicate that the P. falciparum genome contains at least 5 distinct subclasses of large rRNA genes. Dideoxy sequencing of the 5.8S rRNA domain and Northern blot analyses demonstrate that only one subclass is transcribed during the parasite's asexual erythrocytic life cycle.

journal_name

Mol Biochem Parasitol

journal_title

Molecular and biochemical parasitology

authors

Shippen-Lentz D,Afroze T,Vezza AC

doi

10.1016/0166-6851(90)90211-4

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

113-20

issue

1

eissn

0166-6851

issn

1872-9428

pii

0166-6851(90)90211-4

journal_volume

38

pub_type

杂志文章

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