Nanog-induced dedifferentiation of p53-deficient mouse astrocytes into brain cancer stem-like cells.

abstract：:Pentoxyresorufin O-depentylase activity, mainly associated with phenobarbital-inducible cytochrome P450IIB1 (designated CYP2B1), was increased after a single treatment of pyridine (250 mg/kg, i.p.), and further increased by repeated treatments for 5 days. The catalytic activity and immunoreactive protein of CYP2B reco...

journal_title：Biochemical and biophysical research communications

authors： Park KS,Sohn DH,Veech RL,Song BJ

更新日期：1992-06-15 00:00:00

abstract：:Two cyclic AMP-independent protein kinases (CK 1 and CK 2) in the cytosol fraction of AH-66 hepatoma cells have been purified to homogeneity. CK 1 and CK 2 had molecular weights of 36,000 and 340,000, respectively, as determined by gel filtration. CK 1 consists of a single polypeptide and CK 2 is composed of two subun...

journal_title：Biochemical and biophysical research communications

authors： Nakajo S,Shimizu T,Shinkawa K,Nakaya K,Nakamura Y

更新日期：1983-06-29 00:00:00

abstract：:Human Protein tyrosine kinase 6 (PTK6)(EC:2.7.10.2), also known as the breast tumor kinase (BRK), is an intracellular non-receptor Src-related tyrosine kinase expressed five-fold or more in human breast tumors and breast cancer cell lines but its expression being low or completely absent from normal mammary gland. The...

journal_title：Biochemical and biophysical research communications

authors： Thakur MK,Birudukota S,Swaminathan S,Battula SK,Vadivelu S,Tyagi R,Gosu R

更新日期：2017-01-22 00:00:00

abstract：:The understanding of capsid (C) protein interactions with itself would provide important data on how the core is organized in flaviviruses during assembly. In this study, West Nile (WN) virus C protein was shown to form homodimers using yeast two-hybrid analysis in conjunction with mammalian two-hybrid and in vivo co-...

journal_title：Biochemical and biophysical research communications

authors： Bhuvanakantham R,Ng ML

更新日期：2005-04-01 00:00:00

abstract：:The effects of different lysophospholipids on endothelium-dependent hyperpolarization by acetylcholine were examined in rat mesenteric arteries. Lysophosphatidylcholine with 14 or longer carbon acyl chain significantly inhibited the hyperpolarization, while that with 12 or lesser carbon acyl chain was without effect. ...

journal_title：Biochemical and biophysical research communications

authors： Fukao M,Hattori Y,Kanno M,Sakuma I,Kitabatake A

更新日期：1996-10-14 00:00:00

abstract：:Plant sterols are supplemented in foods to reduce cardiovascular risk. Randomized controlled trials show 2 g of plant sterols a day reduce serum cholesterol by about 10%. This reduction in serum cholesterol levels is achieved at the expense of increased serum plant sterol levels. Findings in patients with phytosterole...

journal_title：Biochemical and biophysical research communications

authors： Weingärtner O,Baber R,Teupser D

更新日期：2014-04-11 00:00:00

abstract：:To determine whether insulin resistance increases expression of plasminogen activator inhibitor type-1 (PAI-1) in the heart, studies were performed in 22 mice with and 38 without myocardial infarction. Insulin resistance in transgenic animals genetically rendered insulin resistant was confirmed with the use of intrape...

journal_title：Biochemical and biophysical research communications

authors： Sobel BE,Schneider DJ,Lee YH,Pratley RE

更新日期：2006-07-21 00:00:00

abstract：:Hippo pathway regulates cell proliferation and differentiation. Yes-associated protein (Yap) and transcriptional coactivator with PDZ-binding motif (Taz) are effectors of Hippo pathway. The function of Yap/Taz in embryonic liver development has yet to be reported. Here yap1 and taz were found expressed in liver and ot...

journal_title：Biochemical and biophysical research communications

authors： Yi X,Yu J,Ma C,Li L,Luo L,Li H,Ruan H,Huang H

更新日期：2018-09-03 00:00:00

abstract：:Treatment of the cells of the 311 cell line, a pluripotent mouse teratocarcinoma cell line, with 12-O-tetradecanoylphorbol-13-acetate (TPA) modulates c-mos expression. Transient suppression of 6.1 and 4.6 kilobases (kb) transcripts and activation of 1.8 transcript indicate that TPA mediates concurrently positive and n...

journal_title：Biochemical and biophysical research communications

authors： Ogiso Y,Kitagawa K,Nishino H,Iwashima A

更新日期：1988-07-15 00:00:00

abstract：:Regulation of the retina-specific expression of the interphotoreceptor retinoid-binding protein (IRBP) gene in transgenic mice requires sequences between nucleotide (nt) -156 and +19. DNAse I footprinting and electrophoretic mobility shift assays identified a region between nt -69 and -40 that interacts with some nucl...

journal_title：Biochemical and biophysical research communications

authors： Liou GI,Matragoon S,Overbeek PA,Fei Y

更新日期：1994-09-30 00:00:00

abstract：:2,3 Dehydro-2-deoxy-N-acetyl-neuraminic acid (DNANA) competitively inhibits the neuraminidase activity of Hemagglutinin-neuraminidase (HN) from Sendai virus. The inhibition constant depends on the presence of the Fusion (F) protein, which is 30 microM in the presence of active F protein and 50 microM when the F protei...

journal_title：Biochemical and biophysical research communications

authors： Dallocchio F,Tomasi M,Bellini T

更新日期：1995-03-08 00:00:00

abstract：:Human sera from autoimmune gastritis patients containing autoantibodies to gastric parietal cells were analyzed by immunological methods. Enzyme linked immuno-sorbent assay demonstrated that all nine sera reacted with pig gastric vesicles enriched in H+/K(+)-ATPase (gastric proton pump). Immunoblotting experiments ind...

journal_title：Biochemical and biophysical research communications

authors： Wang XH,Miyazaki Y,Shinomura Y,Moriyama Y,Nakamoto RK,Matsuzawa Y,Maeda M,Futai M

更新日期：1993-01-15 00:00:00

abstract：:In the central nervous system of 11.5-day mouse embryos, the expression of CRABP was spatially restricted to the anteroposterior axis. CRABP was most strongly expressed in the rhombencephalon and the anterior part of the neural tube. In 14-day mouse embryo, CRABP drastically decreased in the brain and the anterior par...

journal_title：Biochemical and biophysical research communications

authors： Momoi T,Hanaoka K,Momoi M

更新日期：1990-06-29 00:00:00

abstract：:Phosphofructokinase of rabbit muscle, which is specific for nucleoside triphosphates such as ATP, dissociated and gained the capability to utilize pyrophosphate as phosphoryl donor following incubation with UDP-glucose. The pyrophosphate- and ATP-linked activities of UDP-glucose-treated muscle phosphofructokinase were...

journal_title：Biochemical and biophysical research communications

authors： Wong JH,Balogh A,Buchanan BB

更新日期：1984-06-29 00:00:00

abstract：:Xanthomonas campestris pv. campestris (Xcc), a close relative to Pseudomonas aeruginosa, is the pathogen causing black rot in cruciferous plants. In P. aeruginosa, FleQ serves as a cognate activator of sigma54 in transcription from several sigma54-dependent promoters of flagellar genes. These P. aeruginosa promoters h...

journal_title：Biochemical and biophysical research communications

authors： Hu RM,Yang TC,Yang SH,Tseng YH

更新日期：2005-10-07 00:00:00

abstract：:A secondary structure has been predicted for the hemorrhagic metalloproteases using a method developed in Zurich that extracts structural information from patterns of conservation and variation in homologous protein sequences. This prediction tests the limits of the method when applied to a small number of homologous ...

journal_title：Biochemical and biophysical research communications

authors： Gerloff DL,Jenny TF,Knecht LJ,Benner SA

更新日期：1993-07-15 00:00:00

abstract：:Elevated Na(+) concentration ([Na(+)]) in the cerebrospinal fluid (CSF) contributes to the development of salt-sensitive hypertension. CSF is formed by the choroid plexus (CP) in cerebral ventricles, and [Na(+)] in CSF is controlled by transporters in CP. Here, we examined the effect of high salt diet on the expressio...

journal_title：Biochemical and biophysical research communications

authors： Guo L,Meng J,Xuan C,Ge J,Sun W,O'Rourke ST,Sun C

更新日期：2015-05-29 00:00:00

abstract：:Amino acid transporter plays an important role in regulating mTOR signaling pathway. This study investigated the effects of reduced dietary protein levels on amino acid transporters and mTOR signaling pathway. A total of 54 weaning pigs were randomly allocated into a 3 × 3 factorial design, followed by slaughtering th...

journal_title：Biochemical and biophysical research communications

authors： Wang D,Wan X,Peng J,Xiong Q,Niu H,Li H,Chai J,Jiang S

更新日期：2017-04-01 00:00:00

abstract：:Adenovirus DNA synthesis carried out in vitro was inhibited by the aphidicolin. However, 30% of the DNA synthesis was resistant to aphidicolin even at a concentration of 200 micrograms/ml. When the distribution patterns of the radioactivity of the products synthesized in the presence of 50 micrograms/ml of the drug wa...

journal_title：Biochemical and biophysical research communications

authors： Ariga H

更新日期：1983-05-31 00:00:00

abstract：:The genome of Saccharomyces cerevisia encodes four mismatch repair MutL proteins and these proteins form three heterocomplexes: Mlh1-Mlh2, Mlh1-Mlh3, and Mlh1-Pms1. Only, the Mlh1-Mlh3 heterocomplex has been implicated specifically in promotion of meiotic crossing-over. In this report, we show that yeast Mlh3 co-immun...

journal_title：Biochemical and biophysical research communications

authors： Wang TF,Kung WM

更新日期：2002-08-30 00:00:00

abstract：:The recognition and removal of interstrand cross-links is perhaps the least understood of all repair pathways in eukaryotic cells. We have shown previously that uncoupling of cross-links occurs in mammalian cell extracts and have identified a number of factors that mediate this process. However, we have not observed c...

journal_title：Biochemical and biophysical research communications

authors： Lu X,Zhang N,Vasquez K,Barton M,Legerski R

更新日期：2005-10-14 00:00:00

abstract：:Pancreatic islets of Langerhans were perifused with Krebs-bicarbonate solution containing glucose (5 and 10 mM). The perifusate was spiked with tetradeuterated hepoxilin A3 and was extracted and analysed by gas chromatography-mass spectrometry using NICI detection. Evidence is presented showing the presence of hepoxil...

journal_title：Biochemical and biophysical research communications

authors： Pace-Asciak CR,Martin JM,Corey EJ,Su WG

更新日期：1985-04-30 00:00:00

abstract：:The specificities of the binding of lung surfactant protein SP-D to glycolipids were examined using 125I-labeled SP-D as a probe. When the binding study was performed on TLC plates, SP-D bound exclusively to GlcCer, whereas it failed to bind to GalCer, GM1, GM2, asialo-GM1, asialo-GM2, sulfatide, Forssman antigen, cer...

journal_title：Biochemical and biophysical research communications

authors： Kuroki Y,Gasa S,Ogasawara Y,Shiratori M,Makita A,Akino T

更新日期：1992-09-16 00:00:00

abstract：:The aim of this study was to investigate the effect of fluctuations in blood glucose levels on atherogenesis. Apolipoprotein (apo) E-deficient mice fed maltose twice daily were used as a model of repetitive postprandial glucose spikes. We investigated the number of macrophages adherent to the endothelium and the area ...

journal_title：Biochemical and biophysical research communications

authors： Mita T,Otsuka A,Azuma K,Uchida T,Ogihara T,Fujitani Y,Hirose T,Mitsumata M,Kawamori R,Watada H

更新日期：2007-07-06 00:00:00

abstract：:Eight amino acid permease genes from the protozoan parasite Leishmania donovani (AAPLDs) were cloned, sequenced, and shown to be expressed in promastigotes. Seven of these belong to the amino acid transporter-1 and one to the amino acid polyamino-choline superfamilies. Using these sequences as well as known and charac...

journal_title：Biochemical and biophysical research communications

authors： Akerman M,Shaked-Mishan P,Mazareb S,Volpin H,Zilberstein D

更新日期：2004-12-03 00:00:00

abstract：:The 3'UTR of eukaryotic mRNA is an important regulation region, on which many trans factors act. In recent years, a series of 3'UTRs were shown to have tumor suppressor function, including the 3'UTR of the human nuclear factor for interleukin-6 (NF-IL6 3'UTR). To understand molecular basis for this function, we have t...

journal_title：Biochemical and biophysical research communications

authors： He YZ,Liu DG

更新日期：2000-09-16 00:00:00

abstract：:Changes in the intermediate filament composition of rat kidney proximal tubule cells in culture have been investigated. The data suggest that differentiated tubular epithelial cells do not express vimentin, but vimentin expression is induced when the cells begin to proliferate in culture. The cultured cells are positi...

journal_title：Biochemical and biophysical research communications

authors： Hatzinger PB,Chen Q,Dong LQ,Stevens JL

更新日期：1988-12-30 00:00:00

abstract：:Post-translational modification (PTM) of proteins plays a crucial role in health and disease by affecting numerous aspects of protein structure, function, stability and subcellular localization. Protein S-nitrosylation is one type of PTM that involves the covalent modification of cysteine sulfhydryl groups with nitric...

journal_title：Biochemical and biophysical research communications

authors： Khatib S,Artoul F,Gershko M,Markman G,Vaya J

更新日期：2014-02-14 00:00:00

abstract：:Alzheimer's disease (AD) pathology is characterized by plaques, tangles, and neuronal cell loss. The main constituent of plaques is beta-amyloid peptide (A beta), a 39-42 residue peptide which has been linked to disruption of calcium homeostasis and neurotoxicity in vitro. We demonstrate that a neurotoxic fragment of ...

journal_title：Biochemical and biophysical research communications

authors： Mirzabekov T,Lin MC,Yuan WL,Marshall PJ,Carman M,Tomaselli K,Lieberburg I,Kagan BL

更新日期：1994-07-29 00:00:00

abstract：:Molecular motors move many intracellular cargos along microtubules. Recently, it has been hypothesized that in vivo cargo velocity can be used to determine the number of engaged motors. We use theoretical and experimental approaches to investigate these assertions, and find that this hypothesis is inconsistent with pr...

journal_title：Biochemical and biophysical research communications

authors： Martinez JE,Vershinin MD,Shubeita GT,Gross SP

更新日期：2007-02-16 00:00:00