A tobacco-related carcinogen: assessing the impact of smoking behaviours of cohabitants on benzene exposure in children.

Abstract:

BACKGROUND:Secondhand smoke (SHS) represents a major preventable cause of morbidity for communities, especially for children, who are more susceptible than adults to the adverse effects of passive smoking. SHS contains several carcinogens, including benzene. OBJECTIVE:To investigate the role of household characteristics and the smoking behaviours of cohabitants in predicting SHS-derived benzene exposure levels. Methods In this cross-sectional study, 122 children (aged 5-11 years old) were selected from a school in rural Italy. Characteristics of their home environment and the smoking habits of the children's cohabitants were obtained via questionnaire, and urinary unmodified benzene (u-UB) and cotinine (a specific nicotine metabolite) levels were determined from spot urine samples. RESULTS:Significant differences between SHS-exposed and SHS-unexposed children were found with respect to u-UB levels (median values 359.50 and 92.50 ng/litre, respectively; p<0.001). The excretion of u-UB increased significantly in parallel to increased SHS exposure as follows: unexposed to SHS (median value 92.50 ng/litre)

journal_name

Tob Control

journal_title

Tobacco control

authors

Protano C,Andreoli R,Manini P,Guidotti M,Vitali M

doi

10.1136/tc.2010.039255

subject

Has Abstract

pub_date

2012-05-01 00:00:00

pages

325-9

issue

3

eissn

0964-4563

issn

1468-3318

pii

tc.2010.039255

journal_volume

21

pub_type

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