Ventricular aneurysms complicating coxsackievirus group B, types 1 and 4 murine myocarditis.

Abstract:

:Suckling Swiss Webster mice were inoculated with 10(4)TCD50 of coxsackieviruses, group B types 1 or 4. Virulent necrotizing myocarditis resulted in 185 infected mice. Of the latter group, three (14.3%) nurslings on the 17th and 23rd day after inoculations had left ventricular aneurysms postmortem. None of 61 concurrently matched control mice developed aneurysms. Ventricular aneurysm is a suggested but previously undocumented complication of murine, and possibly human necrotizing transmural coxsackievirus myocarditis.

journal_name

Circulation

journal_title

Circulation

authors

El-Khatib MR,Chason JL,Lerner AM

doi

10.1161/01.cir.59.2.412

subject

Has Abstract

pub_date

1979-02-01 00:00:00

pages

412-6

issue

2

eissn

0009-7322

issn

1524-4539

journal_volume

59

pub_type

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