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Structure of hepatitis E viral particle.

Abstract：

:Hepatitis E is acute hepatitis caused by infection of hepatitis E virus (HEV) via a fecal-to-oral or zoonotic route. HEV is a small, non-enveloped virus containing positive strand RNA as a genome. Recently, the three-dimensional structures of the HEV-like particles and spike domain protruded from the surface of the particle expressed by recombinant baculovirus or bacteria have been revealed. Based on these reports, the structural features of the HEV capsid subunit and viral particle are reviewed to give insights to the mechanisms underlying the particle assembly, antigenicity, host cell attachment and native virion packaging.

journal_name

Virus Res

journal_title

Virus research

authors

Mori Y,Matsuura Y

doi

10.1016/j.virusres.2011.03.015

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

59-64

issue

1

eissn

0168-1702

issn

1872-7492

pii

S0168-1702(11)00105-5

journal_volume

161

pub_type

杂志文章,评审

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