Antibodies to citrullinated α-enolase peptide 1 and clinical and radiological outcomes in rheumatoid arthritis.

abstract：:Chondromalacia patellae is difficult to diagnosis clinically with accuracy. In order to clarify the relevant symptoms and signs, 78 patients presenting with a clinical diagnosis of chondromalacia were examined by arthroscopy. In 49% of the knees no abnormalities were found. Presenting symptoms were similar in the norm...

journal_title：Annals of the rheumatic diseases

authors： Leslie IJ,Bentley G

更新日期：1978-12-01 00:00:00

abstract：OBJECTIVES:To identify genetic associations with hip osteoarthritis (HOA), we performed a meta-analysis of genome-wide association studies (GWAS) of HOA. METHODS:The GWAS meta-analysis included approximately 2.5 million imputed HapMap single nucleotide polymorphisms (SNPs). HOA cases and controls defined radiographica...

journal_title：Annals of the rheumatic diseases

authors： Evans DS,Cailotto F,Parimi N,Valdes AM,Castaño-Betancourt MC,Liu Y,Kaplan RC,Bidlingmaier M,Vasan RS,Teumer A,Tranah GJ,Nevitt MC,Cummings SR,Orwoll ES,Barrett-Connor E,Renner JB,Jordan JM,Doherty M,Doherty SA,Uitte

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Myeloid inhibitory C-type lectin-like receptor (MICL, Clec12A) is a C-type lectin receptor (CLR) expressed predominantly by myeloid cells. Previous studies have suggested that MICL is involved in controlling inflammation. OBJECTIVE:To determine the role of this CLR in inflammatory pathology using Clec12A(-/...

journal_title：Annals of the rheumatic diseases

authors： Redelinghuys P,Whitehead L,Augello A,Drummond RA,Levesque JM,Vautier S,Reid DM,Kerscher B,Taylor JA,Nigrovic PA,Wright J,Murray GI,Willment JA,Hocking LJ,Fernandes MJ,De Bari C,Mcinnes IB,Brown GD

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To evaluate new classification criteria for peripheral spondyloarthritis (SpA) in patients with SpA with peripheral manifestations only. METHODS:In this Assessment of SpondyloArthritis international Society (ASAS) study, two prespecified sets of criteria were compared against the European Spondylarthropathy ...

journal_title：Annals of the rheumatic diseases

authors： Rudwaleit M,van der Heijde D,Landewé R,Akkoc N,Brandt J,Chou CT,Dougados M,Huang F,Gu J,Kirazli Y,Van den Bosch F,Olivieri I,Roussou E,Scarpato S,Sørensen IJ,Valle-Oñate R,Weber U,Wei J,Sieper J

更新日期：2011-01-01 00:00:00

abstract：:This review assesses the risk assessment of cardiovascular disease (CVD) in rheumatoid arthritis (RA) and how non-invasive imaging modalities may improve risk stratification in future. RA is common and patients are at greater risk of CVD than the general population. Cardiovascular (CV) risk stratification is recommend...

journal_title：Annals of the rheumatic diseases

authors： Fent GJ,Greenwood JP,Plein S,Buch MH

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Medical management of adults with osteoarthritis (OA) who require non-steroidal anti-inflammatory drugs (NSAIDs) must be decided after assessing prevalent gastrointestinal (GI) and cardiovascular (CV) risks in the individual patient. OBJECTIVE:To evaluate the GI and CV risk profile of patients with OA who r...

journal_title：Annals of the rheumatic diseases

authors： Lanas A,Tornero J,Zamorano JL

更新日期：2010-08-01 00:00:00

abstract：:Biological therapies directed at proinflammatory cytokines have irrevocably changed the landscape of treatment of rheumatoid arthritis (RA) and other autoimmune diseases. With the advances in our knowledge in cytokine signalling, the question emerges whether targeting intracellular signalling might also be a safe and ...

journal_title：Annals of the rheumatic diseases

authors： O'Shea JJ,Kontzias A,Yamaoka K,Tanaka Y,Laurence A

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVES:To report 4-year imaging outcomes in the RAPID-axSpA (NCT01087762) study of patients with ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axSpA), treated with certolizumab pegol (CZP). METHODS:This phase III, randomised trial was placebo-controlled and double-blind to week 24, d...

journal_title：Annals of the rheumatic diseases

authors： van der Heijde D,Baraliakos X,Hermann KA,Landewé RBM,Machado PM,Maksymowych WP,Davies OR,de Peyrecave N,Hoepken B,Bauer L,Nurminen T,Braun J

更新日期：2018-05-01 00:00:00

abstract：:In a multicentre study patients with rheumatoid arthritis judged by prevailing criteria to be suitable for synovectomy of the knee or metacarpophalangeal (MCP) joints were randomly allocated to one of two groups. One group had the operation, the other was observed without operation from a notional corresponding date. ...

journal_title：Annals of the rheumatic diseases

authors：

更新日期：1975-10-01 00:00:00

abstract：:Septic arthritis is associated with a definite morbidity which may be related to a delay in diagnosis and hence treatment. The cases of three patients with rheumatoid arthritis and chronic chest disease where the joint sepsis was not the predominant feature are presented. The responsible organism was Streptococcus pne...

journal_title：Annals of the rheumatic diseases

authors： Morley PK,Hull RG,Hall MA

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVE:This randomised, double-blind, parallel-group, phase 3 study compared monotherapy with sirukumab, an anti-interleukin-6 cytokine monoclonal antibody, with adalimumab monotherapy in patients with rheumatoid arthritis (RA). METHODS:Biologic-naïve patients with active RA who were inadequate responders or were i...

journal_title：Annals of the rheumatic diseases

authors： Taylor PC,Schiff MH,Wang Q,Jiang Y,Zhuang Y,Kurrasch R,Daga S,Rao R,Tak PP,Hsu B

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To assess the diagnostic value of ultrasonography (US) in the evaluation of arthritic shoulder joints. METHODS:Twenty shoulders of 20 inpatients with arthritis were evaluated by US one day before the shoulder operation. Changes in the subacromial-subdeltoid bursa, biceps tendon and tendon sheath, rotatof cuf...

journal_title：Annals of the rheumatic diseases

authors： Alasaarela E,Leppilahti J,Hakala M

更新日期：1998-06-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is an autoimmune disease characterised by chronic inflammation of the joints. Anti-citrullinated protein antibodies (ACPA) are highly specific for RA and are associated with a more severe disease progression. ACPA have also been shown to have a pathological role in RA. In animal models of RA,...

journal_title：Annals of the rheumatic diseases

authors： Suurmond J,Schuerwegh AJ,Toes RE

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:Target trial emulation is an intuitive design framework that encourages investigators to formulate their comparative effectiveness research (CER) question as a hypothetical randomised controlled trial (RCT). Our aim was to systematically review CER studies in rheumatoid arthritis (RA) to provide examples of ...

journal_title：Annals of the rheumatic diseases

authors： Zhao SS,Lyu H,Solomon DH,Yoshida K

更新日期：2020-07-01 00:00:00

abstract：:Recent data are presented which indicate a critical role for interleukin (IL)-18 in rheumatoid arthritis (RA). The T cells and macrophages invading the synovium or in the synovial fluid are the chief cellular targets of IL-18 in RA. Neutrophils, dendritic cells and endothelial cells may also be cellular mediators of I...

journal_title：Annals of the rheumatic diseases

authors： Dai SM,Shan ZZ,Xu H,Nishioka K

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:In a prospective observational study, we investigated whether patients with active systemic lupus erythematosus (SLE) had higher indices of endothelial damage and dysfunction than healthy controls and whether improved disease control was associated with improvement in these indices. METHODS:Twenty-seven pat...

journal_title：Annals of the rheumatic diseases

authors： Parker B,Al-Husain A,Pemberton P,Yates AP,Ho P,Gorodkin R,Teh LS,Alexander MY,Bruce IN

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND AIM:Striving for harmonisation of specialty training and excellence of care in rheumatology, the European League Against Rheumatism (EULAR) established a task force to develop points to consider (PtCs) for the assessment of competences during rheumatology specialty training. METHODS:A systematic literat...

journal_title：Annals of the rheumatic diseases

authors： Sivera F,Alunno A,Najm A,Avcin T,Baraliakos X,Bijlsma JW,Badreh S,Burmester G,Cikes N,Da Silva JA,Damjanov N,Dougados M,Dudler J,Edwards CJ,Iagnocco A,Lioté F,Nikiphorou E,van Onna M,Stones SR,Vassilopoulos D,Hain

更新日期：2021-01-01 00:00:00

abstract：:The prevalence of mild and severe radiological osteoarthritis was investigated in a random sample of 6585 inhabitants of a Dutch village. Radiographs were graded 0-4 according to the criteria described by Kellgren and Lawrence. The prevalence of radiological osteoarthritis increased strongly with age and was highest f...

journal_title：Annals of the rheumatic diseases

authors： van Saase JL,van Romunde LK,Cats A,Vandenbroucke JP,Valkenburg HA

更新日期：1989-04-01 00:00:00

abstract：AIM:To assess the prevalence and the nature of autonomic neuropathy (AN) in 17 patients with inactive or mild active systemic lupus erythematosus (SLE). METHODS:Patients were tested using questionnaires related to possible AN symptoms, and four non invasive cardiovascular autonomic function tests at rest, during lying...

journal_title：Annals of the rheumatic diseases

authors： Lioté F,Osterland CK

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:To assess survival and identify predictors of survival in patients with systemic sclerosis-interstitial lung disease (SSc-ILD) who participated in the Scleroderma Lung Studies (SLS) I and II. METHODS:SLS I randomised 158 patients with SSc-ILD to 1  year of oral cyclophosphamide (CYC) vs placebo. SLS II rando...

journal_title：Annals of the rheumatic diseases

authors： Volkmann ER,Tashkin DP,Sim M,Li N,Goldmuntz E,Keyes-Elstein L,Pinckney A,Furst DE,Clements PJ,Khanna D,Steen V,Schraufnagel DE,Arami S,Hsu V,Roth MD,Elashoff RM,Sullivan KM,SLS I and SLS II study groups.

更新日期：2019-01-01 00:00:00

abstract：:Atlanto-axial subluxation occurs with a frequency varying from 6% to 45% in rheumatoid arthritis. Most patients are treated conservatively with a cervical collar. The effectiveness of different cervical collars in inhibiting anterior atlanto-axial subluxation was tested in 11 patients with classical rheumatoid arthrit...

journal_title：Annals of the rheumatic diseases

authors： Althoff B,Goldie IF

更新日期：1980-10-01 00:00:00

abstract：:The relation between the basal and stimulated gastric acid secretion, plasma gastrin, and the gastric microflora was examined in 45 patients with rheumatoid arthritis. Sixteen patients (36%) had basal achlorhydria, and of these, 10 (22%) had achlorhydria or hypochlorhydria after stimulation with pentagastrin. The peak...

journal_title：Annals of the rheumatic diseases

authors： Henriksson K,Uvnäs-Moberg K,Nord CE,Johansson C,Gullberg R

更新日期：1986-06-01 00:00:00

abstract：:Results are reported from the first prospective study of gout in New Zealand Maoris based on a sample of 388 males and 378 females. At baseline, high mean levels of serum uric acid (SUA) were found, 0.422 +/- 0.092 mmol/1 (7.05 +/- 1.54 mg/100 ml) in males and 0.350 +/- 0.091 mmol/1 (5.85 +/- 1.52 mg/100 ml) in female...

journal_title：Annals of the rheumatic diseases

authors： Brauer GW,Prior IA

更新日期：1978-10-01 00:00:00

abstract：AIMS:The aim of this work was to assess the feasibility of using dynamic contrast enhanced (DCE) MRI of bone marrow oedema, to compare it with conventional marrow oedema scoring systems, and to determine the effects of anti-tumour necrosis factor (TNF)alpha therapy. METHODS:The wrist and metacarpophalangeal (MCP) join...

journal_title：Annals of the rheumatic diseases

authors： Hodgson R,Grainger A,O'Connor P,Barnes T,Connolly S,Moots R

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVES:Pyogenic arthritis, pyoderma gangrenosum and acne (PAPA) syndrome is characterised by flares of sterile arthritis with neutrophil infiltrate and the overproduction of interleukin (IL)-1β. The purpose of this study was to elucidate the potential role of neutrophil subsets and neutrophil extracellular traps (N...

journal_title：Annals of the rheumatic diseases

authors： Mistry P,Carmona-Rivera C,Ombrello AK,Hoffmann P,Seto NL,Jones A,Stone DL,Naz F,Carlucci P,Dell'Orso S,Gutierrez-Cruz G,Sun HW,Kastner DL,Aksentijevich I,Kaplan MJ

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:Factors contributing to the development of systemic lupus erythematosus (SLE) remain largely unknown although are likely to include both environmental and genetic components. Studies on murine lupus have indicated a role for an antibody that blocks binding of cytotoxic T lymphocyte associated-4 (CTLA-4) to B...

journal_title：Annals of the rheumatic diseases

authors： Heward J,Gordon C,Allahabadia A,Barnett AH,Franklyn JA,Gough SC

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVES:To study the role of two COL2A1 single nucleotide polymorphisms (rs3737548 and rs2276455) and their haplotypes in individual susceptibility to osteoarthritis (OA) of the hand in Finnish women. METHODS:Bilateral hand radiographs of 543 Finnish female dentists and teachers aged 45-63 years were examined and c...

journal_title：Annals of the rheumatic diseases

authors： Hämäläinen S,Solovieva S,Hirvonen A,Vehmas T,Takala EP,Riihimäki H,Leino-Arjas P

更新日期：2009-10-01 00:00:00

abstract：:In view of the association of congenital heart block with maternal antibody to cellular antigen Ro (SSA), and one report linking anti-Ro with myocarditis in a patient with myositis an association between anti-Ro antibodies and cardiac disease was sought in adults with systemic lupus erythematosus (SLE). Among 67 patie...

journal_title：Annals of the rheumatic diseases

authors： Logar D,Kveder T,Rozman B,Dobovisek J

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:To investigate the role of CD8 cell subsets in the pathogenesis of rheumatoid arthritis (RA) and the phenotypes of T cells adherent or non-adherent to the target cells (endothelial cells and synovial cells) pre-treated with IL-1 beta. METHODS:The expression of S6F1 on CD8 cells and that of an activation mark...

journal_title：Annals of the rheumatic diseases

authors： Ueki Y,Eguchi K,Miyake S,Nagataki S,Tominaga Y

更新日期：1994-12-01 00:00:00

abstract：:While rheumatoid-factor-producing haemolytic plaque-forming cells (RF--PFC) of the human peripheral blood were easily inhibited by cycloheximide, mouse spleen cells immune to sheep red cells (anti-SRC PFC) were inhibited only after prolonged preincubation in the drug. The RF--PFC were easily inhibited by propranolol, ...

journal_title：Annals of the rheumatic diseases

authors： Moore TL,Rose JE,Vaughan JH

更新日期：1979-06-01 00:00:00