IL-1 has no direct role in the IGF-1 non-responsive state during experimentally induced arthritis in mouse knee joints.

abstract：:A previously normal 58-year-old woman developed a widespread psoriatic rash and asymmetrical peripheral polyarthritis a week after beginning treatment with oxprenolol for hypertension. Skin and joint disease resolved simultaneously after drug withdrawal and have not recurred. ...

journal_title：Annals of the rheumatic diseases

authors： Macfarlane DG,Settas L

更新日期：1984-02-01 00:00:00

abstract：OBJECTIVE:To measure interleukin (IL)18 serum concentrations in patients with rheumatoid arthritis (RA) undergoing infliximab treatment (tumour necrosis factor (TNF) alpha blockade) and to evaluate the concomitant modification of IL12 and IL13 serum concentrations, two cytokines belonging to the Th1 and Th2 profile res...

journal_title：Annals of the rheumatic diseases

authors： Pittoni V,Bombardieri M,Spinelli FR,Scrivo R,Alessandri C,Conti F,Spadaro A,Valesini G

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVES:(a)To determine the accuracy and reliability of arthroscopic measurements of cartilage lesion diameter in an artificial right knee model; (b) to determine whether the use of a set of variable angle elongated probes improves performance; and (c) to identify other sources of variability. METHODS:Ovoid "lesion...

journal_title：Annals of the rheumatic diseases

authors： Oakley SP,Portek I,Szomor Z,Turnbull A,Murrell GA,Kirkham BW,Lassere MN

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Although there has been major progress in gout imaging, no gout classification criteria currently include advanced imaging techniques. OBJECTIVE:To examine the usefulness of imaging modalities in the classification of gout when compared to monosodium urate (MSU) crystal confirmation as the gold standard, in...

journal_title：Annals of the rheumatic diseases

authors： Ogdie A,Taylor WJ,Weatherall M,Fransen J,Jansen TL,Neogi T,Schumacher HR,Dalbeth N

更新日期：2015-10-01 00:00:00

abstract：:Fifteen consecutive patients with acute arthritis were studied. Careful culture and microscopy of swabs from mucosal sites were performed to examine the hypothesis that the acute tropical polyarthritis commonly seen in Zimbabwe is due to undiagnosed gonococcal infection. Rheumatic fever and Reiter's disease accounted ...

journal_title：Annals of the rheumatic diseases

authors： Stein CM,Hanly MG

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Osteoarthritis is the most frequent chronic joint disease causing pain and disability. Besides biomechanical mechanisms, the pathogenesis of osteoarthritis may involve inflammation, vascular alterations and dysregulation of lipid metabolism. As statins are able to modulate many of these processes, this study...

journal_title：Annals of the rheumatic diseases

authors： Clockaerts S,Van Osch GJ,Bastiaansen-Jenniskens YM,Verhaar JA,Van Glabbeek F,Van Meurs JB,Kerkhof HJ,Hofman A,Stricker BH,Bierma-Zeinstra SM

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:Hospitalisation is a risk factor for flares in people with gout. However, the predictors of inpatient gout flare are not well understood. The aim of this study was to develop a prediction model for inpatient gout flare among people with comorbid gout. METHODS:We used data from a retrospective cohort of hosp...

journal_title：Annals of the rheumatic diseases

authors： Jatuworapruk K,Grainger R,Dalbeth N,Taylor WJ

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:To understand the use of tumour necrosis factor (TNF)alpha inhibitors in refractory dermatomyositis and polymyositis in an academic centre. METHODS:A retrospective study of eight patients with dermatomyositis or polymyositis refractory to corticosteroids and immunosuppressives who were treated with TNF inhib...

journal_title：Annals of the rheumatic diseases

authors： Efthimiou P,Schwartzman S,Kagen LJ

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVES:Different prevalences of generalised osteoarthritis (GOA) in patients with knee and hip OA have been reported. The aim of this investigation was to evaluate radiographic and clinical patterns of disease in a hospital based population of patient subgroups with advanced hip and knee OA and to compare the preva...

journal_title：Annals of the rheumatic diseases

authors： Günther KP,Stürmer T,Sauerland S,Zeissig I,Sun Y,Kessler S,Scharf HP,Brenner H,Puhl W

更新日期：1998-12-01 00:00:00

abstract：:In a double blind, single observer, 48 week study the effects of sulphasalazine (2 g daily) and hydroxychloroquine (400 mg daily months 0-6, thereafter 200 mg daily) were compared in 60 patients with definite or classical rheumatoid arthritis. They had not been treated previously with second line drugs. The onset of r...

journal_title：Annals of the rheumatic diseases

authors： Nuver-Zwart IH,van Riel PL,van de Putte LB,Gribnau FW

更新日期：1989-05-01 00:00:00

abstract：:We report two patients with systemic lupus erythematosus who subsequently developed thrombotic thrombocytopenic purpura. In each case the coexistence of these two conditions was confirmed by pathological findings. Both patients responded to treatment, but one eventually died. A review of the literature suggests a poss...

journal_title：Annals of the rheumatic diseases

authors： Fox DA,Faix JD,Coblyn J,Fraser P,Smith B,Weinblatt ME

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND:Vascular damage is a key pathological process in systemic sclerosis (SSc) and accounts for significant disease-related morbidity. To determine the clinical burden of severe digital vasculopathy (SDV), we have reviewed hospital-based treatment for this important complication of SSc in a large single centre co...

journal_title：Annals of the rheumatic diseases

authors： Nihtyanova SI,Brough GM,Black CM,Denton CP

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To propose e-learning methods that address the fundamental problems related to sonographic training in rheumatology. METHODS:The project was designed for rheumatologists with strong motivation to learn ultrasound. A modular approach was constructed, consisting of a basic 3-day residential course, followed by...

journal_title：Annals of the rheumatic diseases

authors： Filippucci E,Meenagh G,Ciapetti A,Iagnocco A,Taggart A,Grassi W

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety between tocilizumab added to methotrexate and tocilizumab switched from methotrexate in patients with active rheumatoid arthritis (RA). METHODS:This is a 2-year randomised, controlled study. RA patients with moderate or high disease activity despite methotrexate were random...

journal_title：Annals of the rheumatic diseases

authors： Kaneko Y,Atsumi T,Tanaka Y,Inoo M,Kobayashi-Haraoka H,Amano K,Miyata M,Murakawa Y,Yasuoka H,Hirata S,Nagasawa H,Tanaka E,Miyasaka N,Yamanaka H,Yamamoto K,Takeuchi T

更新日期：2016-11-01 00:00:00

abstract：:A 49 year old white woman with systemic lupus erythematosus and bronchiolitis obliterans was treated with prednisone (1 mg/kg daily), which led to a transitory improvement in pulmonary status. Cyclophosphamide was then added--4 mg/kg daily intravenously for five days, then 2 mg/kg daily orally--and this was followed b...

journal_title：Annals of the rheumatic diseases

authors： Godeau B,Cormier C,Menkes CJ

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:To develop and validate new classification criteria for adult and juvenile idiopathic inflammatory myopathies (IIM) and their major subgroups. METHODS:Candidate variables were assembled from published criteria and expert opinion using consensus methodology. Data were collected from 47 rheumatology, dermatolo...

journal_title：Annals of the rheumatic diseases

authors： Lundberg IE,Tjärnlund A,Bottai M,Werth VP,Pilkington C,Visser M,Alfredsson L,Amato AA,Barohn RJ,Liang MH,Singh JA,Aggarwal R,Arnardottir S,Chinoy H,Cooper RG,Dankó K,Dimachkie MM,Feldman BM,Torre IG,Gordon P,Hayas

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Systemic lupus erythematosus (SLE) is characterised by the presence of antibodies to double stranded DNA (dsDNA), which are involved in the pathogenesis of SLE. Previous studies showed that at least two thirds of patients develop a clinical relapse within six months after a significant rise in the anti-dsDNA...

journal_title：Annals of the rheumatic diseases

authors： Bijl M,Horst G,Bootsma H,Limburg PC,Kallenberg CG

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:To assess the diagnostic value of ultrasonography (US) in the evaluation of arthritic shoulder joints. METHODS:Twenty shoulders of 20 inpatients with arthritis were evaluated by US one day before the shoulder operation. Changes in the subacromial-subdeltoid bursa, biceps tendon and tendon sheath, rotatof cuf...

journal_title：Annals of the rheumatic diseases

authors： Alasaarela E,Leppilahti J,Hakala M

更新日期：1998-06-01 00:00:00

abstract：:The aetiology of Reiter's syndrome (RS) is unknown. In order to evaluate the role of immunological mechanisms in this disease we performed synovial biopsies on 12 patients with RS looking for deposition of immunoglobulins and complement components in synovial tissue. By immunofluorescent techniques 11 synovia were fou...

journal_title：Annals of the rheumatic diseases

authors： Baldassare AR,Weiss TD,Tsai CC,Arthur RE,Moore TL,Zuckner J

更新日期：1981-06-01 00:00:00

abstract：:One hundred acute geriatric inpatients were assessed to investigate the prevalence of shoulder disorders; 21 had symptoms due to shoulder disease. Conditions included supraspinatus tendinitis (five), chronic rotator cuff rupture (seven), frozen shoulder (two), glenohumeral osteoarthritis (two), apatite related shoulde...

journal_title：Annals of the rheumatic diseases

authors： Chard MD,Hazleman BL

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:To determine whether a multimodal physiotherapy programme including taping, exercises, and massage is effective for knee osteoarthritis, and if benefits can be maintained with self management. METHODS:Randomised, double blind, placebo controlled trial; 140 community volunteers with knee osteoarthritis partic...

journal_title：Annals of the rheumatic diseases

authors： Bennell KL,Hinman RS,Metcalf BR,Buchbinder R,McConnell J,McColl G,Green S,Crossley KM

更新日期：2005-06-01 00:00:00

abstract：:OBJECTIVE: To examine the risk of major cardiovascular disease associated with non-steroidal anti-inflammatory drugs (NSAIDs) in a large 'real-world' contemporary rheumatoid arthritis (RA) cohort. METHODS: A longitudinal cohort study was conducted with use of Danish nationwide individual-level registry data on inpat...

journal_title：Annals of the rheumatic diseases

authors： Lindhardsen J,Gislason GH,Jacobsen S,Ahlehoff O,Olsen AM,Madsen OR,Torp-Pedersen C,Hansen PR

更新日期：2014-08-01 00:00:00

abstract：:A patient with systemic lupus erythematosus who developed pneumococcal epiglottitis is described and the literature reviewed. This infection is extremely rare in adults, and only 10 cases, none of them with SLE, have so far been reported. Epiglottitis is usually caused by Haemophilus influenzae. However, in immunocomp...

journal_title：Annals of the rheumatic diseases

authors： Shalit M,Gross DJ,Levo Y

更新日期：1982-12-01 00:00:00

abstract：OBJECTIVE:To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine (HCQ). METHODS:The case records of women (n = 33) exposed to HCQ during their pregnancies (n = 36) and of 53 control patients from a single lupus pregnancy centre were reviewed to determine lupus ac...

journal_title：Annals of the rheumatic diseases

authors： Buchanan NM,Toubi E,Khamashta MA,Lima F,Kerslake S,Hughes GR

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:To determine whether mild variation in acetabular depth (AD) and shape is a risk factor for osteoarthritis (OA) of the hip. METHODS:The unaffected contralateral hip of patients with unilateral hip OA was compared with hips of asymptomatic controls without hip OA, derived from the Nottingham Genetics Osteoart...

journal_title：Annals of the rheumatic diseases

authors： McWilliams DF,Doherty SA,Jenkins WD,Maciewicz RA,Muir KR,Zhang W,Doherty M

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:To assess the prevalence and patterns of cardiac abnormalities as detected by cardiac magnetic resonance imaging (MRI) in systemic sclerosis (SSc). METHODS:Fifty-two consecutive patients with SSc underwent cardiac MRI to determine morphological, functional, perfusion at rest and delayed enhancement abnormal...

journal_title：Annals of the rheumatic diseases

authors： Hachulla AL,Launay D,Gaxotte V,de Groote P,Lamblin N,Devos P,Hatron PY,Beregi JP,Hachulla E

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:To maintain and optimise the quality of care provided by health professionals in rheumatology (HPRs), adequate educational offerings are needed. This task force (TF) aimed to develop evidence-based recommendations for the generic core competences of HPRs, with specific reference to nurses, physica...

journal_title：Annals of the rheumatic diseases

authors： Edelaar L,Nikiphorou E,Fragoulis GE,Iagnocco A,Haines C,Bakkers M,Barbosa L,Cikes N,Ndosi M,Primdahl J,Prior Y,Pchelnikova P,Ritschl V,Schäfer VS,Smucrova H,Storrønning I,Testa M,Wiek D,Vliet Vlieland TPM

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To examine the effects of smoking on cartilage loss and pain at the knee in individuals with knee osteoarthritis. METHODS:159 men with symptomatic knee osteoarthritis who participated in a 30-month, prospective, natural history study of knee osteoarthritis were examined. The more symptomatic knee was imaged ...

journal_title：Annals of the rheumatic diseases

authors： Amin S,Niu J,Guermazi A,Grigoryan M,Hunter DJ,Clancy M,LaValley MP,Genant HK,Felson DT

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Persistent fibroblast activation initiated by transforming growth factor β (TGF-β) is a fundamental event in the pathogenesis of systemic sclerosis, and its pharmacological inhibition represents a potential therapeutic strategy. The nuclear receptor, peroxisome proliferator-activated receptor γ (PPAR-γ), exe...

journal_title：Annals of the rheumatic diseases

authors： Wei J,Zhu H,Komura K,Lord G,Tomcik M,Wang W,Doniparthi S,Tamaki Z,Hinchcliff M,Distler JH,Varga J

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:Advances in health measurement have led to the application of Rasch Item Response Theory (IRT) analysis (Rasch analysis) to evaluate instruments measuring health status and quality of life of patients, including the Health Assessment Questionnaire and SF-36. This study investigated the extent to which the Wes...

journal_title：Annals of the rheumatic diseases

authors： Wolfe F,Kong SX

更新日期：1999-09-01 00:00:00