Bronchiolitis obliterans in systemic lupus erythematosus: beneficial effect of intravenous cyclophosphamide.

abstract：OBJECTIVE:To examine the effect of infliximab plus methotrexate (MTX) compared with placebo plus MTX on bone loss in patients with early rheumatoid arthritis (RA) in a double-blind randomised study design. Further, to explore the associations between bone loss and markers of RA disease. METHODS:All 20 patients with RA...

journal_title：Annals of the rheumatic diseases

authors： Haugeberg G,Conaghan PG,Quinn M,Emery P

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To investigate the long-term effects of induction therapy with adalimumab (ADA) plus methotrexate (MTX) in comparison with placebo (PBO) plus MTX in DMARD-naïve patients with active early rheumatoid arthritis (RA). METHODS:Patients with active early RA (disease duration of ≤12 months) were randomly assigned ...

journal_title：Annals of the rheumatic diseases

authors： Detert J,Bastian H,Listing J,Weiß A,Wassenberg S,Liebhaber A,Rockwitz K,Alten R,Krüger K,Rau R,Simon C,Gremmelsbacher E,Braun T,Marsmann B,Höhne-Zimmer V,Egerer K,Buttgereit F,Burmester GR

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:To evaluate coronary atherosclerosis in patients with psoriatic arthritis (PsA) and control subjects using coronary CT angiography (CCTA). METHODS:Ninety consecutive patients with PsA (male: 56(62.2%); 50.3±11.1 years) were recruited. 240 controls (male: 137(57.1%); 49.6±10.7 years) without known cardiovasc...

journal_title：Annals of the rheumatic diseases

authors： Shen J,Wong KT,Cheng IT,Shang Q,Li EK,Wong P,Kun EW,Law MY,Yip R,Yim I,Ying S,Li M,Li TK,Wong CK,Zhu TY,Lee JJ,Chang M,Lee AP,Tam LS

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:To assess and characterise the risk of bladder cancer, and its relation to cyclophosphamide, in patients with Wegener's granulomatosis. METHODS:In the population based, nationwide Swedish Inpatient Register a cohort of 1065 patients with Wegener's granulomatosis, 1969-95, was identified. Through linkage with...

journal_title：Annals of the rheumatic diseases

authors： Knight A,Askling J,Granath F,Sparen P,Ekbom A

更新日期：2004-10-01 00:00:00

abstract：:The effect of the intra-articular injection of radioactive erbium 169 and yttrium 90 on the growth of the leg in rabbits has been studied. I colloid state these isotopes are used clinically for synovial ablation. These beta emitters slow down bone growth in proportion to the amount of radioactivity injected. If the jo...

journal_title：Annals of the rheumatic diseases

authors： Rebut-Bonneton C,Roucayrol JC,Delbarre F

更新日期：1975-12-01 00:00:00

abstract：OBJECTIVES:Hyperplasia of synovial fibroblasts, infiltration with lymphocytes and tissue hypoxia are major characteristics of rheumatoid arthritis (RA). Extensive data support a key role for toll-like receptors (TLRs) in RA. Little is known regarding the impact of hypoxia on TLR-induced inflammation in RA. The aim of t...

journal_title：Annals of the rheumatic diseases

authors： Hu F,Mu R,Zhu J,Shi L,Li Y,Liu X,Shao W,Li G,Li M,Su Y,Cohen PL,Qiu X,Li Z

更新日期：2014-05-01 00:00:00

abstract：:Reproducibility along a vertical 10 cm visual analogue scale (VAS) was investigated. Eight normal volunteers attempted to duplicate a set of marked VAS. There was a tendency to estimate too high on the scale, and reproducibility was found to be variable along its length. This indicates that the error involved in the u...

journal_title：Annals of the rheumatic diseases

authors： Dixon JS,Bird HA

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:The MEFV gene is responsible for familial Mediterranean fever (FMF). Several disease associated mutations have been identified. The range of genetic variation in MEFV in Greek patients has not been determined. OBJECTIVE:To describe a method that facilitates the routine screening of the entire coding sequenc...

journal_title：Annals of the rheumatic diseases

authors： Ritis K,Giaglis S,Spathari N,Micheli A,Zonios D,Tzoanopoulos D,Deltas CC,Rafail S,Mean R,Papadopoulos V,Tzioufas AG,Moutsopoulos HM,Kartalis G

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVES:To develop recommendations for monitoring patients with systemic lupus erythematosus (SLE) in clinical practice and observational studies and to develop a standardised core set of variables to monitor SLE. METHODS:We followed the European League Against Rheumatism (EULAR) standardised procedures for guideli...

journal_title：Annals of the rheumatic diseases

authors： Mosca M,Tani C,Aringer M,Bombardieri S,Boumpas D,Brey R,Cervera R,Doria A,Jayne D,Khamashta MA,Kuhn A,Gordon C,Petri M,Rekvig OP,Schneider M,Sherer Y,Shoenfeld Y,Smolen JS,Talarico R,Tincani A,van Vollenhoven RF,

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:To compare glucose tolerance and parameters of insulin sensitivity and β-cell function between chronic glucocorticoid (GC)-using and GC-naive patients with rheumatoid arthritis (RA). METHODS:Frequently sampled 75 g oral glucose tolerance tests were performed in 58 chronic GC-using and 82 GC-naive patients w...

journal_title：Annals of the rheumatic diseases

authors： Hoes JN,van der Goes MC,van Raalte DH,van der Zijl NJ,den Uyl D,Lems WF,Lafeber FP,Jacobs JW,Welsing PM,Diamant M,Bijlsma JW

更新日期：2011-11-01 00:00:00

abstract：:Two cases of acute monarthritis secondary to asymptomatic renal cell carcinoma are described. This association has not previously been reported. The patients were initially thought to have a septic arthritis, but hot spots were seen on isotope bone scans and biopsy samples showed secondary neoplasms, which were later ...

journal_title：Annals of the rheumatic diseases

authors： Chakravarty KK,Webley M

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Since the publication of the European League Against Rheumatism (EULAR) recommendations for the management of large vessel vasculitis (LVV) in 2009, several relevant randomised clinical trials and cohort analyses have been published, which have the potential to change clinical care and therefore supporting t...

journal_title：Annals of the rheumatic diseases

authors： Hellmich B,Agueda A,Monti S,Buttgereit F,de Boysson H,Brouwer E,Cassie R,Cid MC,Dasgupta B,Dejaco C,Hatemi G,Hollinger N,Mahr A,Mollan SP,Mukhtyar C,Ponte C,Salvarani C,Sivakumar R,Tian X,Tomasson G,Turesson C,S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA), psoriatic arthritis (PsA) and other spondylarthritides impose a great impact on the individual in addition to the costs on society, which may be reduced by effective pharmacological treatment. Industry-independent health economic studies should complement studies sponsored by indus...

journal_title：Annals of the rheumatic diseases

authors： Gülfe A,Kristensen LE,Saxne T,Jacobsson LT,Petersson IF,Geborek P

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:The first genome-wide association study (GWAS) of systemic sclerosis (SSc) demonstrated three non-major histocompatibility complex (MHC) susceptibility loci. The goal of this study was to investigate the impact of these gene variants on survival and severity of interstitial lung disease (ILD) in SSc. METHODS...

journal_title：Annals of the rheumatic diseases

authors： Sharif R,Mayes MD,Tan FK,Gorlova OY,Hummers LK,Shah AA,Furst DE,Khanna D,Martin J,Bossini-Castillo L,Gonzalez EB,Ying J,Draeger HT,Agarwal SK,Reveille JD,Arnett FC,Wigley FM,Assassi S

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:To examine objectively spatial patterns of osteophytes around the distal end of the femur and to identify distinct subgroups. METHODS:A sample of 107 human femora from a large skeletal population were selected for study. These femora included subjects with evidence of late stage osteoarthritis (that is, wit...

journal_title：Annals of the rheumatic diseases

authors： Shepstone L,Rogers J,Kirwan J,Silverman B

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Optimal treatment for rheumatoid arthritis (RA) after inadequate response (IR) to tumour necrosis factor α inhibitors (TNFi) remains uncertain. OBJECTIVE:To compare the efficacy and safety of biological agents after TNFi-IR. METHODS:A systematic literature search was carried out using Medline and Cochrane ...

journal_title：Annals of the rheumatic diseases

authors： Schoels M,Aletaha D,Smolen JS,Wong JB

更新日期：2012-08-01 00:00:00

abstract：:The early changes (five weeks) in the structure of newly synthesised and endogenous articular cartilage sulphated proteoglycans were studied in lapine IgG induced experimental immune synovitis. Rabbits with immune synovitis (IS-IgG) were compared with animals with a developed hypersensitivity to IgG (I-IgG) and with n...

journal_title：Annals of the rheumatic diseases

authors： Malemud CJ,Yoo JU,Goldberg VM,Kresina TF

更新日期：1987-07-01 00:00:00

abstract：:Recent data are presented which indicate a critical role for interleukin (IL)-18 in rheumatoid arthritis (RA). The T cells and macrophages invading the synovium or in the synovial fluid are the chief cellular targets of IL-18 in RA. Neutrophils, dendritic cells and endothelial cells may also be cellular mediators of I...

journal_title：Annals of the rheumatic diseases

authors： Dai SM,Shan ZZ,Xu H,Nishioka K

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:To compare the effects of etanercept (ETN) 50 mg once weekly plus methotrexate (MTX) versus MTX alone on patient-reported outcomes (PROs) and the relationship between remission and PRO improvement. METHODS:In this double-blind, randomised clinical trial (COMET), PROs included: the Health Assessment Question...

journal_title：Annals of the rheumatic diseases

authors： Kekow J,Moots RJ,Emery P,Durez P,Koenig A,Singh A,Pedersen R,Robertson D,Freundlich B,Sato R

更新日期：2010-01-01 00:00:00

abstract：:Thirteen patients were studied after jejunoileal bypass (JIB) surgery. Seven developed arthritis and six did not. Circulating immune complexes containing IgG and IgA were detected in the sera of patients with and without arthritis. IgA complexes were shown to contain secretory component, a protein predominantly associ...

journal_title：Annals of the rheumatic diseases

authors： Clegg DO,Zone JJ,Samuelson CO Jr,Ward JR

更新日期：1985-04-01 00:00:00

abstract：:The effects of fasting for 7 days were investigated in 13 patients with rheumatoid arthritis (RA) in comparison with a control regimen in a cross-over trial. The effects of fasting on clinical performance and blood neutrophil functions were studied. During fasting, with a mean weight loss of 5.1 kg, clinical inflammat...

journal_title：Annals of the rheumatic diseases

authors： Udén AM,Trang L,Venizelos N,Palmblad J

更新日期：1983-02-01 00:00:00

abstract：OBJECTIVES:To investigate whether bortezomib, a proteasome inhibitor approved for treatment of multiple myeloma, induces clinically relevant plasma cell (PC) depletion in patients with active, refractory systemic lupus erythematosus (SLE). METHODS:Twelve patients received a median of two (range 1-4) 21-day cycles of i...

journal_title：Annals of the rheumatic diseases

authors： Alexander T,Sarfert R,Klotsche J,Kühl AA,Rubbert-Roth A,Lorenz HM,Rech J,Hoyer BF,Cheng Q,Waka A,Taddeo A,Wiesener M,Schett G,Burmester GR,Radbruch A,Hiepe F,Voll RE

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:People with spondyloarthritis (SpA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) have identified the importance of understanding how their disease and its treatment impacts on their social roles. This requires a reliable and valid standardised measure, and this study evaluates these measurement...

journal_title：Annals of the rheumatic diseases

authors： Davis AM,Palaganas MP,Badley EM,Gladman DD,Inman RD,Gignac MA

更新日期：2011-10-01 00:00:00

abstract：:To understand better a complex disease such as psoriatic arthritis (PsA), collection of a large amount of information on clinical, laboratory, and radiological features is required over an extended period of time. Longitudinal data can be effectively collected and stored in clinical registries and databases. This arti...

journal_title：Annals of the rheumatic diseases

authors： Gladman DD,Ritchlin C,Helliwell PS

更新日期：2005-03-01 00:00:00

abstract：:Three patients presented with septal fasciitis and panniculitis, associated with clinical and laboratory features which precluded straight-forward classification into eosinophilic fasciitis, localised scleroderma, or lupus erythematosus profundus. Treatment with cimetidine caused the remission of cutaneous manifestati...

journal_title：Annals of the rheumatic diseases

authors： Naschitz JE,Yeshurun D,Rosner I,Abrahamson JE,Misselevitch I,Boss JH

更新日期：1990-10-01 00:00:00

abstract：:Erosions on the triquetrum and pisiform are frequent in early rheumatoid arthritis and occur characteristically at 3 sites. (a) A shallow erosion on the proximal medial triquetral "bare" area is related to synovial proliferation at the margin of the radiocarpal cavity, although compressive forces from an adjacent long...

journal_title：Annals of the rheumatic diseases

authors： Resnick D

更新日期：1976-02-01 00:00:00

abstract：OBJECTIVES:To evaluate the long-term efficacy and safety of canakinumab to treat patients with colchicine-resistant familial Mediterranean fever (crFMF) during Epoch 4 (weeks 41 to 113) of the CLUSTER study. METHODS:Patients received open-label canakinumab 150 or 300 mg, every 4 or 8 weeks during a 72-week period. We ...

journal_title：Annals of the rheumatic diseases

authors： Ozen S,Ben-Cherit E,Foeldvari I,Amarilyo G,Ozdogan H,Vanderschueren S,Marzan K,Kahlenberg JM,Dekker E,De Benedetti F,Koné-Paut I

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:To compare patterns of arteriographic lesions of the aorta and primary branches in patients with Takayasu's arteritis (TAK) and giant cell arteritis (GCA). METHODS:Patients were selected from two North American cohorts of TAK and GCA. The frequency of arteriographic lesions was calculated for 15 large arter...

journal_title：Annals of the rheumatic diseases

authors： Grayson PC,Maksimowicz-McKinnon K,Clark TM,Tomasson G,Cuthbertson D,Carette S,Khalidi NA,Langford CA,Monach PA,Seo P,Warrington KJ,Ytterberg SR,Hoffman GS,Merkel PA,Vasculitis Clinical Research Consortium.

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:The differential diagnosis of seronegative rheumatoid arthritis (negRA) and psoriasis arthritis (PsA) is often difficult due to the similarity of symptoms and the unavailability of reliable clinical markers. Since chronic inflammation induces major changes in the serum metabolome and lipidome, we tested whet...

journal_title：Annals of the rheumatic diseases

authors： Souto-Carneiro M,Tóth L,Behnisch R,Urbach K,Klika KD,Carvalho RA,Lorenz HM

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Anti-tumour necrosis factor (TNF) treatment is clinically efficacious in patients with active ankylosing spondylitis (AS) and leads to improvement of spinal inflammation, as assessed by magnetic resonance imaging. It is unclear whether anti-TNF treatment affects chronic spinal changes in AS. OBJECTIVES:To a...

journal_title：Annals of the rheumatic diseases

authors： Baraliakos X,Listing J,Rudwaleit M,Brandt J,Sieper J,Braun J

更新日期：2005-10-01 00:00:00