Abstract:
:Primary closure in dermatologic surgery is state of the art in small lesions at the head, but also in larger lesions at the trunk or the extremities. Microcirculatory effects on the skin blood flow near to the wound edges affected by primary closure. Forty three patients were investigated. Before and after surgery, skin blood flow was measured using Laser Doppler Fluxmetry (LDF). During primary closure, tension in the suture was measured and the tension on the wound edges was calculated. Times series were analyzed using continuous wavelet analyses, before, after 2 h and 24 h after surgery. After three months, the cosmetic results were requested. Median horizontal diameter was 22 mm (quartiles 20/48 mm), median vertical diameter was 44 mm (quartiles 26/60 mm). Mean string force was 12.0 SD 10.2 N. During the whole course of investigation, we found no change of microcirculatory parameters such as mean LDF or any scaling level following wavelet analysis caused by primary closure. Average of the cosmetic result was 1.8. It is a relative small number of patients and the defects are located in different areas. Skin blood flow and the microcirculatory pattern is not affected in the area by the tension on wound edges and provides therefore a fast healing process without any vegetatively induced complications even if the string force is high. In dermatosurgery, wounds can be closed directly without changing the microcirculatory pattern in the direct area of the wound margins.
journal_name
Clin Hemorheol Microcircjournal_title
Clinical hemorheology and microcirculationauthors
Häfner HM,Bräuer K,Kneilling M,Moehrle M,Breuninger Hdoi
10.3233/CH-2010-1371subject
Has Abstractpub_date
2011-01-01 00:00:00pages
99-109issue
2eissn
1386-0291issn
1875-8622pii
72R8886LHKNW303Rjournal_volume
47pub_type
杂志文章abstract::Erythrocytes kept outside the blood circulation undergo progressive changes in metabolism, shape and function, which was the topic of this study. For that purpose, blood anticoagulated with either heparin, citrate or EDTA was incubated at temperatures of 5°C, 22°C or 37°C for 0 h, 24 h and 48 h, respectively. A temper...
journal_title:Clinical hemorheology and microcirculation
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journal_title:Clinical hemorheology and microcirculation
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journal_title:Clinical hemorheology and microcirculation
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journal_title:Clinical hemorheology and microcirculation
pub_type: 临床试验,杂志文章
doi:
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doi:
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doi:
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更新日期:2001-01-01 00:00:00
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更新日期:1997-01-01 00:00:00
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