Comparison of erythrocyte aggregability changes during ischemic and hemorrhagic stroke.

Abstract:

:The aim of this work was to perform a comparative investigation of erythrocyte aggregability changes in the peripheral and cerebral circulation during ischemic and hemorrhagic stroke. Subjects of the present study were patients with ischemic brain infarcts (14 patients) and with hemorrhagic stroke (21 patients) from the Intensive Care Unit of the Institute of Neurology and Neurosurgery. The blood samples were obtained from the following blood vessels: the common carotid artery carrying blood to the primarily damaged brain hemisphere, both jugular veins carrying blood from the primarily damaged and the contralateral hemispheres, as well as from the cubital vein to obtain specimens of the systemically circulating blood. Erythrocyte aggregation was evaluated by using the "Georgian technique". We found that the RBC aggregation indices increased in both the regional as well as the systemic circulation of the hemorrhagic stroke patients as compared to ischemic stroke patients. The results of the present study demonstrate different changes of erythrocyte aggregation in ischemic and hemorrhagic stroke patients. Therefore, the role of blood rheological properties in their pathogenesis seems also to be different.

authors

Bolokadze N,Lobjanidze I,Momtselidze N,Shakarishvili R,Mchedlishvili G

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

265-7

issue

1-2

eissn

1386-0291

issn

1875-8622

journal_volume

35

pub_type

杂志文章
  • Monitoring of RBC rheology after cryopreservation to detect autologous blood doping in vivo? A pilot study.

    abstract:BACKGROUND:Autologous blood doping (ABD) is applied to improve performance capacity. ABD includes blood donation, red blood cell (RBC) storage at -80°C and re-infusion prior to or during competition. ABD is not directly detectable with current detection techniques. OBJECTIVE:Since cryopreservation is known to affect R...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-200887

    authors: Bizjak DA,Grolle A,Urena JAN,Bloch W,Deitenbeck R,Grau M

    更新日期:2020-01-01 00:00:00

  • Sequential analysis of erythrocyte aggregation in health and diseases.

    abstract::Aggregation of erythrocytes requires prolonged interaction of cellular and plasma constituents similar to in vivo conditions. To achieve this and then to analyse this process in various clinical and laboratory conditions, a PC-AT based system is developed. The erythrocyte suspension at 5% hematocrit in plasma is place...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:

    authors: Singh M,Kumaravel M

    更新日期:1997-07-01 00:00:00

  • Erythrocytes dynamic viscoelasticity in beta-thalassaemia minor.

    abstract::Beta-thalassaemia is a hereditary hemolytic disease, in which each clinic phenotype encompasses a heterogenic group of genetic alterations resulting in beta-globin chain synthesis decrease or absence in red blood cells. Studies on beta-thalassaemia carriers suggest the existence of decreased red cell deformability. Th...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:

    authors: Pérez SM,Riquelme B,Acosta I,Valverde J,Milani A

    更新日期:2006-01-01 00:00:00

  • Attenuating effect of Myakuryu on mesenteric microcirculatory disorders induced by ischemia and reperfusion.

    abstract::Myakuryu (MR) is a newly developed herbal medicine composing Crataegue oinnatifida bge (COB), Panax notoginseng (PN) and Ginkyo biloba (GB). To examine the effectiveness of MR, we investigated its effects on rat mesenteric microcirculatory injury induced by ischemia/reperfusion (I/R). The mesenteric microcirculation o...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:

    authors: Han JY,Horie Y,Li D,Akiba Y,Nagata H,Miura S,Oda M,Ishii H,Hibi T

    更新日期:2006-01-01 00:00:00

  • Plasma viscosity in female patients with hypothyroidism: effects of oxidative stress and cholesterol.

    abstract::Hypothyroidism is associated with atherosclerotic events, however, the mechanism is unclear. We investigated the effects of oxidative stress and cholesterol on plasma viscosity in female patients with hypothyroidism (n = 20; mean age: 45.5 +/- 5.5 years) at baseline and after L-thyroxine replacement therapy (average d...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:

    authors: Konukoglu D,Ercan M,Hatemi H

    更新日期:2002-01-01 00:00:00

  • Regular physical activity alters the postocclusive reactive hyperemia of the cutaneous microcirculation.

    abstract::Regular physical activity leads to increased endothelium-dependent vasodilatation. Postocclusive reactive hyperemia (PRH) is a transient increase of blood flow after the release of an arterial occlusion and has been used as a clinical tool to estimate endothelial function. The aim of our study was to assess the potent...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 临床试验,杂志文章

    doi:10.3233/CH-2010-1320

    authors: Lenasi H,Strucl M

    更新日期:2010-01-01 00:00:00

  • Discussion on the relationship between normal hematocrit and geographical factors in China.

    abstract::This paper is written in order to provide a scientific basis for laying out an unified standard of the reference value of hematocrit of Chinese healthy people. It studies the relationship between the reference values of Chinese adults' hematocrit, tested according to the Wintrobe Laws and five geographical factors. It...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:

    authors: Miao G,Yan Y,Chuanmin Z,Naiying L

    更新日期:1997-11-01 00:00:00

  • Methods in hemorheology and their clinical applications1.

    abstract::The lecture was presented during the Fåhraeus award ceremony for 2016 at the University of Lisbon. It summarizes the main results and some of the more important hemorheological contributions achieved in the Laboratory of Biodynamics and Biorheology of the Institute of Mechanics to BAS and in collaboration with other l...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-168001

    authors: Antonova N

    更新日期:2016-01-01 00:00:00

  • Possible involvement of oxidative stress in exercise-mediated platelet activation.

    abstract::In this study, we have attempted to verify whether a single bout of strenuous exercise performed by sedentary healthy individuals may interfere with the mechanisms controlling platelet sensitivity through exercise-related modifications of plasma oxidant/antioxidant equilibrium. Strenuous exercise resulted in an increa...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:

    authors: Di Massimo C,Scarpelli P,Tozzi-Ciancarelli MG

    更新日期:2004-01-01 00:00:00

  • Combined use of strain elastography and superb microvascular imaging with grayscale ultrasound according to the BI-RADS classification for differentiating benign from malignant solid breast masses.

    abstract:OBJECTIVE:To evaluate the combined use of strain elastography (SE) and superb microvascular imaging (SMI) with grayscale ultrasound (US) according to the Breast Imaging Reporting and Data System (BI-RADS) classification for differentiating benign from malignant breast masses. METHODS:In total, 166 patients with 177 br...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-190693

    authors: Liang M,Ou B,Wu J,Xiao X,Ruan J,Tian J,Xu X,Wang B,Yang H,Luo B

    更新日期:2020-01-01 00:00:00

  • The knockout of urea transporter-B improves the hemorheological properties of erythrocyte.

    abstract:OBJECTIVE:Urea transporter-B (UT-B), highly expressed in erythrocyte, confers specific permeability to urea, urea analogues and water. The purpose of this study was to determine the hemorheological properties of UT-B null erythrocyte using a series of biophysical techniques. METHODS AND RESULTS:The blood was taken fro...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-16174

    authors: Geng X,Lei T,Zhou H,Yao W,Xin W,Yang B

    更新日期:2017-01-01 00:00:00

  • Erythrocyte as a biological sensor.

    abstract::The erythrocytes ability of sensing the local oxygen gradient through the hemoglobin conformation, along with changes in nitric oxide mobilization and vasomotor repercussions at the microcirculation, were reviewed in detail in this article. Different approachs trying to explain the erythrocyte death were additionally ...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章,评审

    doi:10.3233/CH-2011-1512

    authors: Lopes de Almeida JP,Oliveira S,Saldanha C

    更新日期:2012-01-01 00:00:00

  • Altitude training induced alterations in erythrocyte rheological properties: a controlled comparison study in rats.

    abstract::Altitude training is frequently used by athletes to improve sea-level performance. However, the objective benefits of altitude training are controversial. This study aimed to investigate the possible alterations in hemorheological parameters in response to altitude training. Sprague Dawley rats, were divided into 6 gr...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-131711

    authors: Bor-Kucukatay M,Colak R,Erken G,Kilic-Toprak E,Kucukatay V

    更新日期:2014-01-01 00:00:00

  • Use of contrast-enhanced ultrasound to monitor rabbit renal ischemia-reperfusion injury and correlations between time-intensity curve parameters and renal ICAM-1 expression.

    abstract:BACKGROUND:Renal ischemia-reperfusion injury (IRI) is common in renal transplantation, shock, and nephrolithotomy. OBJECTIVE:To quantitatively assess rabbit renal IRI with contrast-enhanced ultrasound (CEUS) and investigate associations between renal cortical time-intensity curve (TIC) parameters and intracellular adh...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-131768

    authors: Li M,Luo Z,Chen X,Xuan J,Ye F,Liu H,Chen K

    更新日期:2015-01-01 00:00:00

  • Effects of nimodipine combined with betahistine on CRP and other inflammatory cytokines and vascular endothelial function in patients with hypertensive cerebral vasospasm.

    abstract:OBJECTIVE:This study aims to investigate the effect of nimodipine combined with betahistine on the levels of CRP and other inflammatory cytokines, as well as vascular endothelial function in patients with hypertensive cerebral vasospasm. METHODS:A total of 80 patients with hypertensive cerebral vasospasm from March 20...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-190589

    authors: Liu X,Zhao N,Zeng K,Xiao P,Sheng P,Luo X,Wang Y

    更新日期:2020-01-01 00:00:00

  • Hemorheological disturbances in cerebrovascular diseases.

    abstract::The aim of the study was to evaluate the possible relationship of the hemorheological disturbances with the clinical symptoms and some risk factors (RF) for cerebrovascular diseases (CVD). The study included 68 patients with CVD, 29 with transient ischemic attacks (TIA) and 39 with chronic unilateral cerebral infarcti...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:

    authors: Velcheva I,Antonova N,Titianova E,Damianov P,Dimitrov N,Dimitrova V

    更新日期:2008-01-01 00:00:00

  • Studies on the aggregation behaviour of pegylated human red blood cells with the Zeta sedimentation technique.

    abstract::Covalent binding of poly(ethylene glycol), abbreviated as PEG, to red blood cells (RBC) surface leads to masking of the RBC blood group determinants and the PEG layer on the cell surface sterically hinders RBC-RBC and RBC-plasma protein interactions. We cross-linked linear mPEG-SPA of various molecular mass (2000, 500...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:

    authors: Jovtchev S,Stoeff S,Arnold K,Zschörnig O

    更新日期:2008-01-01 00:00:00

  • Absent post-ischemic increase of blood flowmotion in the cutaneous microcirculation of healthy chronic cigarette smokers.

    abstract::The aim of the study was to investigate whether chronic cigarette smoke habit is associated with changes of laser Doppler (LD) skin blood flowmotion (SBF). We performed spectral analysis of skin forearm LD signal detected by a LD flowmetry (Periflux PF4, Perimed, Sweden) before and during forearm post-ischemic hyperae...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:

    authors: Rossi M,Carpi A,Di Maria C,Galetta F,Santoro G

    更新日期:2007-01-01 00:00:00

  • Non-invasive contrast enhanced ultrasound for quantitative assessment of tumor microcirculation. Contrast mixed mode examination vs. only contrast enhanced ultrasound examination.

    abstract:PURPOSE:To evaluate the different ultrasound techniques for quantification of contrast enhanced ultrasound (CEUS) in an experimental rat prostate carcinoma model. METHOD AND MATERIALS:Prostate carcinoma (MLLB-2) cells were subcutaneously injected into the right flank of male rat (Charles River, Sulzfeld, Germany, 180 ...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-2010-1341

    authors: Paprottka PM,Cyran CC,Zengel P,von Einem J,Wintersperger B,Nikolaou K,Reiser MF,Clevert DA

    更新日期:2010-01-01 00:00:00

  • Changes in the microcirculation at the superficial and deeper levels in lymphoedema: the effects and results of massage, compression, exercise and benzopyrones on these levels during treatment.

    abstract::This review starts with a brief description of the pioneering work done by J.R. Casley-Smith when he looked at the pathophysiological changes that occur, and transport from the blood vessels, through the interstitium to the lymphatics and lymphatic uptake, with the electron microscope. Collaboration with, and further ...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:

    authors: Casley-Smith JR

    更新日期:2000-01-01 00:00:00

  • Increased dense erythrocytes in flame-burned patients.

    abstract:OBJECTIVE:We have studied dense erythrocytes separated on Arabinogalactan (Stractan) ultracentrifuged gradients in flame-burned patients and in normal individuals. In each case, the percentage of erythrocytes in the densest layers was increased when compared to age and sex matched controls. METHODS AND RESULTS:Using a...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-2012-1556

    authors: Saavedra AP,Warth JA,Burke JF,Norton KJ,Gelfand JA

    更新日期:2013-01-01 00:00:00

  • Exposure of human neutrophils to oxygen radicals causes loss of deformability, lipid peroxidation, protein degradation, respiratory burst activation and loss of migration.

    abstract::The effects of oxygen radical generating system of H(2)O(2) on neutrophil deformability, lipid peroxidation, protein degradation, chemotaxis, random migration and activation were studied in the presence and absence of selected anti-oxidants such as vitamin E and carbon monoxide. Hydrogen peroxide caused a significant ...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:

    authors: Abu-Khader AA,Bilto YY

    更新日期:2002-01-01 00:00:00

  • Biological risk factors for deep vein trombosis.

    abstract::Hypercoagulable states due either to inherited or acquired thrombotic risk factors are only present in approximately half of cases of DVT, but the causes in the other half, remain unknown. The importance of biological risk factors such as hyperlipidemia, hypofibrinolysis and hemorheological alterations in the pathogen...

    journal_title:Clinical hemorheology and microcirculation

    pub_type:

    doi:

    authors: Vayá A,Mira Y,Martínez M,Villa P,Ferrando F,Estellés A,Corella D,Aznar J

    更新日期:2002-01-01 00:00:00

  • Divisive influence of interleukin-1 receptor antagonist polymorphisms in melanoma patients.

    abstract:OBJECTIVE:The interleukin-1 receptor antagonist (IL-1RA) contributes to tumor survival and progression in multiple cancer entities. IL-1RA polymorphisms influence IL-1RA expression patterns and function. A known polymorphism was correlated with clinical outcomes in melanoma patients with particularly aggressive disease...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-179212

    authors: Broer PN,Aung T,Heidekrueger PI,Prantl L,Narayan D

    更新日期:2017-01-01 00:00:00

  • Contrast enhanced ultrasound (CEUS) and time intensity curve (TIC) analysis in compartment syndrome: first results.

    abstract:OBJECTIVE:Purpose of this study was to monitor changes of microcirculation in acute compartment syndrome using contrast enhanced ultrasound (CEUS) and to assess the modified perfusion with a special quantification software. METHODS:8 patients with trauma of the lower limb or the upper extremity were enrolled after acu...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-2011-1438

    authors: Geis S,Gehmert S,Lamby P,Zellner J,Pfeifer C,Prantl L,Jung EM

    更新日期:2012-01-01 00:00:00

  • Does Virtual Touch IQ elastography help to improve the preoperative diagnosis of parotid tumors: A prospective trial.

    abstract:BACKGROUND:It is difficult to assess tumors of the parotid gland preoperatively. However, it is essential for the surgeon to know which kind of tumor is present. Ultrasound is the method of choice, but there is still no reliable differential diagnostic tool for determining whether a tumor is malignant or benign. OBJEC...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-179223

    authors: Zengel P,Notter F,Reichel CA,Clevert DA

    更新日期:2017-01-01 00:00:00

  • Cocaine induces a reversible stomatocytosis of red blood cells and increases blood viscosity.

    abstract::Severe side effects of cocaine consumption are vasoocclusive events such as myocardial infarction and stroke. We have hypothesized that cocaine could affect red blood cells (RBCs) and alter the rheological behaviour of blood. Heparinized blood from healthy volunteers was incubated with a final hematocrit of 45% with i...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-2012-1638

    authors: Cagienard F,Schulzki T,Furlong P,Reinhart WH

    更新日期:2013-01-01 00:00:00

  • Multipolar RFA of the liver: Influence of intrahepatic vessels on ablation zones and appropriateness of CECT in detecting ablation dimensions - Results of an in-vivo porcine liver model.

    abstract:BACKGROUND:Radiofrequency ablation (RFA) is an important treatment option for hepatic tumors and metastases. Post-ablation recurrence rates are reported up to 36.5 percent and seem to depend on tumor size, intrahepatic localization of tumors and adjacent hepatic vessels. Multipolar RFA has the potential to overcome/red...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-189313

    authors: Vahldiek JL,Erxleben C,Bressem KK,Gemeinhardt O,Poch F,Hiebl B,Lehmann KS,Hamm B,Niehues SM

    更新日期:2018-01-01 00:00:00

  • Wavelet analysis of skin blood flow in dermatosurgery using primary closure with tension.

    abstract::Primary closure in dermatologic surgery is state of the art in small lesions at the head, but also in larger lesions at the trunk or the extremities. Microcirculatory effects on the skin blood flow near to the wound edges affected by primary closure. Forty three patients were investigated. Before and after surgery, sk...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-2010-1371

    authors: Häfner HM,Bräuer K,Kneilling M,Moehrle M,Breuninger H

    更新日期:2011-01-01 00:00:00

  • Folate receptor mediated genetic modification of human mesenchymal stem cells via folic acid-polyethylenimine-grafted poly(N-3-hydroxypropyl)aspartamide.

    abstract::Mesenchymal stem cells (MSCs) are targeted as vehicles for cell mediated gene therapy. Here we report on a macromolecular carrier, which was designed aiming at successful targeted gene delivery into MSCs through the mediation of folate receptor and reduced cytotoxicity compared to established cationic polymer vector -...

    journal_title:Clinical hemorheology and microcirculation

    pub_type: 杂志文章

    doi:10.3233/CH-179209

    authors: Wang W,Li W,Wang J,Hu Q,Balk M,Bieback K,Stamm C,Jung F,Tang G,Lendlein A,Ma N

    更新日期:2017-01-01 00:00:00