Protective effect of tetramethylpyrazine and salvianolic acid B on apoptosis of rat cerebral microvascular endothelial cell under high shear stress.

abstract：:Hypercoagulable states due either to inherited or acquired thrombotic risk factors are only present in approximately half of cases of DVT, but the causes in the other half, remain unknown. The importance of biological risk factors such as hyperlipidemia, hypofibrinolysis and hemorheological alterations in the pathogen...

journal_title：Clinical hemorheology and microcirculation

authors： Vayá A,Mira Y,Martínez M,Villa P,Ferrando F,Estellés A,Corella D,Aznar J

更新日期：2002-01-01 00:00:00

abstract：:Development of new drugs is a sophisticated process that requires several, different methods. In our experiments we have applied two rheological models to study experimental and clinically used drugs. The antioxidant properties of several agents were estimated by erythrocyte filtration technique. The known antioxidant...

journal_title：Clinical hemorheology and microcirculation

authors： Marton Z,Halmosi R,Alexy T,Horvath B,Toth A,Feher G,Koltai K,Kesmarky G,Habon T,Sumegi B,Hideg K,Toth K

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The ability to evaluate tumor development within experimental oncology is of upmost importance. However, determining tumor volumes in 3D in vivo tumor models is challenging. The chick chorioallantoic membrane (CAM) model represents an optimized xenograft model that surpasses many disadvantages that are inher...

journal_title：Clinical hemorheology and microcirculation

authors： Troebs J,Asam C,Pion E,Prantl L,Aung T,Haerteis S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Platelet activation is associated with abdominal obesity and exercise training is an important modulator of body weight. OBJECTIVE:We investigated the effects of two high intensity interval exercise (HIIE) protocols of different intensity and duration on platelet indices and platelet aggregation in overweig...

journal_title：Clinical hemorheology and microcirculation

authors： Ahmadizad S,Rahmani H,Khosravi N,Falakdin Z,Connes P,Daraei A

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:As most clinical studies measure whole blood viscosity (WBV) from peripheral samples, potential differences in WBV obtained from the coronary arteries are often ignored. This study investigated differences in WBV measured from coronary artery specimens in patients with and without acute coronary syndrome (AC...

journal_title：Clinical hemorheology and microcirculation

authors： Lee SR,Jung JM,Jung LY,Lee JH,Lee SH,Rhee KS,Chae JK,Kim WH,Ko JK,Lee DH,Rosenson RS

更新日期：2013-01-01 00:00:00

abstract：:There are few studies on haemorheological disturbances in morbidly obese patients. The role played by the metabolic syndrome on the rheological profile of morbidly obese subjects has not yet been established, and it is not clear whether morbidly obese, but "metabolically healthy", show rheological alterations. We aime...

journal_title：Clinical hemorheology and microcirculation

authors： Vayá A,Hernández-Mijares A,Suescun M,Solá E,Cámara R,Romagnoli M,Bautista D,Laiz B

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To investigate the role and potential mechanism of Toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB) signaling pathway in cognitive impairment induced by cerebral small vascular disease (CSVD), so as to provide a reference for the clinical treatment of CSVD-induced cognitive impairment. METHODS:Mice...

journal_title：Clinical hemorheology and microcirculation

authors： Zhang Y,Wu R,Gu C,Gao F,Hu X,Zang P,Dong T

更新日期：2019-01-01 00:00:00

abstract：:Radiofrequency ablation (RFA) has shown to be a reasonable alternative for the treatment of hepatic tumors and metastases although multiple limitations remain. Cooling effects due to larger vessels can prevent complete coverage and may lead to early tumor relapse. This preliminary in vivo pig study combines the use of...

journal_title：Clinical hemorheology and microcirculation

authors： Vahldiek JL,Lehmann KS,Poch F,Zurbuchen U,Kreis ME,Gemeinhardt O,Hamm B,Niehues SM

更新日期：2014-01-01 00:00:00

abstract：:The rheological properties of human leukocytes (WBCs) have been studied using the micropipette aspiration and the filtration technique. Partial micropipette (i.d. 2.8-4.5 microm) aspiration of individual leukocytes under constant aspiration pressure of 8 mm H20 and measurement of the aspirated length as a function of ...

journal_title：Clinical hemorheology and microcirculation

authors： Athanassiou G,Matsouka P,Kaleridis V,Missirlis Y

更新日期：2000-01-01 00:00:00

abstract：:The radial dispersion of red blood cells (RBCs) near the vessel wall can significantly affect the transport dynamics in small vessels. The radial dispersion of RBCs is mainly caused by collisions between RBCs and this can be enhanced by aggregation. The objective of this study is to numerically investigate on the effe...

journal_title：Clinical hemorheology and microcirculation

authors： Ju M,Leo HL,Kim S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The reconstruction of metacarpal- and interphalangeal joints after severe hand injuries has been proven to be challenging. Commonly used procedures like arthrodesis, amputation or ray resection of the finger compromise the functionality of the injured finger. Especially for young patients, the restoration of...

journal_title：Clinical hemorheology and microcirculation

authors： Bachleitner K,Blank B,Klein S,Geis S,Aung T,Prantl L,Dolderer JH

更新日期：2016-01-01 00:00:00

abstract：:Shear stress is known to induce platelet activation and aggregation. The red blood cell (RBC) aggregation test requires the application of shear stress for the cells to disaggregate for initialization. We tested the hypothesis that applying shear stress may activate platelets, which can influence RBC aggregation. The ...

journal_title：Clinical hemorheology and microcirculation

authors： Kim JH,Lee H,Lee BK,Shin S

更新日期：2016-01-01 00:00:00

abstract：:The lipoprotein lipase deficient (LPL-/-) mice and high fat-diet (HFD) induced hypertriglyceridemic mice were used to investigate the effects of cardiotonic pill (CP) on RBC rheologic abnormalities. Mice were randomly divided into the following five groups: the control group; the untreated HFD group; the untreated LPL...

journal_title：Clinical hemorheology and microcirculation

authors： Wang XW,Guo J,Wang XF,Chen XP,Wen ZY

更新日期：2008-01-01 00:00:00

abstract：:A variety of medical grade polymeric materials are used in tissue engineering and biomedical technology. Dense non-porous polymeric foils were used as substrates for endothelial cell layers. Half a the test samples (polymers and control materials) were seeded with bovine corneal endothelial cells (BCEC) which more or ...

journal_title：Clinical hemorheology and microcirculation

authors： Hoepken S,Fuhrmann R,Jung F,Franke RP

更新日期：2009-01-01 00:00:00

abstract：:In this study, the effect of the angiotensin-converting-enzyme inhibitor (ACE inhibitor) Ramipril (5 mg/day) and calcium antagonist Isradipin (5 mg/day) treatment of two groups of hypertensive patients (n = 22 in each of group) was evaluated. The parameters of the hemorheological profile (blood and plasma viscosity, r...

journal_title：Clinical hemorheology and microcirculation

authors： Muravyov AV,Zaitsev LG,Muravyov AA,Yakusevich VV,Sirotkina AM

更新日期：1998-07-01 00:00:00

abstract：:In Chinese traditional medicine, angelica is widely used for its known clinical effects of ameliorating blood microcirculation. But the mechanism of these beneficial effects still remains unclear. In this work the rheological behaviour of human erythrocytes treated by angelica was studied in vitro. Normal RBCs incubat...

journal_title：Clinical hemorheology and microcirculation

authors： Wang X,Wei L,Ouyang JP,Muller S,Gentils M,Cauchois G,Stoltz JF

更新日期：2001-01-01 00:00:00

abstract：:Recently, it was shown that mesenchymal stem cells (MSCs) are capable of differentiating into endothelial cells which highlights the potential role of MSCs in neovascularization. In the present study, we investigated the paracrine factors responsible for tube formation in human adipose-tissue derived stem cells (ASCs)...

journal_title：Clinical hemorheology and microcirculation

authors： Gehmert S,Gehmert S,Hidayat M,Sultan M,Berner A,Klein S,Zellner J,Müller M,Prantl L

更新日期：2011-01-01 00:00:00

abstract：:Hypothyroidism is associated with atherosclerotic events, however, the mechanism is unclear. We investigated the effects of oxidative stress and cholesterol on plasma viscosity in female patients with hypothyroidism (n = 20; mean age: 45.5 +/- 5.5 years) at baseline and after L-thyroxine replacement therapy (average d...

journal_title：Clinical hemorheology and microcirculation

authors： Konukoglu D,Ercan M,Hatemi H

更新日期：2002-01-01 00:00:00

abstract：:Polycarbonate (PC) substrate is well suited for culturing human mesenchymal stem cells (MSCs) with high proliferation rate, low cell apoptosis rate and negligible cytotoxic effects. However, little is known about the influence of PC on MSC activity including senescence, differentiation and secretion. In this study, th...

journal_title：Clinical hemorheology and microcirculation

authors： Zou J,Wang W,Kratz K,Xu X,Nie Y,Ma N,Lendlein A

更新日期：2018-01-01 00:00:00

abstract：:Antiangiogenic activity of curcumin on the tumor neogenesis was investigated by evaluating the density of neocapillaries induced by Hepatocellular carcinoma cells (HepG2) in mice, using intravital fluorescence videomicroscopy. Male BALB/c nude mice (20-25 g) were used, and a dorsal skin-fold chamber was implanted. Hep...

journal_title：Clinical hemorheology and microcirculation

authors： Yoysungnoen P,Wirachwong P,Bhattarakosol P,Niimi H,Patumraj S

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Renal failure is a disease with accelerated atherosclerosis beginning with endothelial cell dysfunction. Factors affecting endothelial cell dysfunction include whole blood viscosity (WBV) and asymmetric dimethylarginine (ADMA). The relationship in controls and renal failure was determined. METHODS:51 subjec...

journal_title：Clinical hemorheology and microcirculation

authors： Hammes MS,Watson S,Coe FL,Ahmed F,Beltran E,Dhar P

更新日期：2015-01-01 00:00:00

abstract：:Severe side effects of cocaine consumption are vasoocclusive events such as myocardial infarction and stroke. We have hypothesized that cocaine could affect red blood cells (RBCs) and alter the rheological behaviour of blood. Heparinized blood from healthy volunteers was incubated with a final hematocrit of 45% with i...

journal_title：Clinical hemorheology and microcirculation

authors： Cagienard F,Schulzki T,Furlong P,Reinhart WH

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Focal therapy (FT) of the prostate for low risk prostate cancer (PCa) is an alternative to traditional definite treatment options like external beam radiotherapy or radical prostatectomy. However, follow up after FT is still challenging and is subject to current studies. Significance of imaging after FT su...

journal_title：Clinical hemorheology and microcirculation

authors： Apfelbeck M,Chaloupka M,Schlenker B,Stief CG,Clevert DA

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:The interleukin-1 receptor antagonist (IL-1RA) contributes to tumor survival and progression in multiple cancer entities. IL-1RA polymorphisms influence IL-1RA expression patterns and function. A known polymorphism was correlated with clinical outcomes in melanoma patients with particularly aggressive disease...

journal_title：Clinical hemorheology and microcirculation

authors： Broer PN,Aung T,Heidekrueger PI,Prantl L,Narayan D

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:To evaluate the combination of conventional ultrasound (US) and acoustic radiation force impulse (ARFI) elastography in predicting triple-negative breast cancer and the likelihood of lymphatic metastasis. MATERIALS AND METHODS:A total of 178 women presenting from May 2013 to September 2015 with pathologically ...

journal_title：Clinical hemorheology and microcirculation

authors： Pu H,Zhao LX,Yao MH,Xu G,Liu H,Xu HX,Wu R

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:To identify the associated factors for malignancy in partially cystic thyroid nodules (PCTNs) on ultrasound (US). MATERIALS AND METHODS:This is a retrospective study. 338 PCTNs confirmed by surgery was included in this study. The US features of the nodules were reviewed and their significance in differentia...

journal_title：Clinical hemorheology and microcirculation

authors： Shi YZ,Jin Y,Zheng L

更新日期：2020-01-01 00:00:00

abstract：:Although there are several studies dealing with erythrocyte deformability (ED) in obese patients, research on this topic in morbidly obese subjects is scarce. In these studies ED seems to be decreased, although the cause remains unknown. A case-control study in 76 morbid obese subjects (23 women and 53 men, aged 44 ± ...

journal_title：Clinical hemorheology and microcirculation

authors： Vayá A,Cámara R,Hernádez-Mijares A,Romagnoli M,Solá E,Corella D,Laiz B

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:Obstructive diseases of the salivary glands are often based on Sialolithiasis; however, conventional radiological imaging or ultrasound does not provide a diagnosis in 5-10% of all cases. It was the aim of our study to examine the effectiveness and viability of an intraductal applied contrast-enhanced ultrasoun...

journal_title：Clinical hemorheology and microcirculation

authors： Zengel P,Siedek V,Berghaus A,Clevert DA

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Tetrahydrobiopterin (BH4), an endogenous nucleic acid derivative, acts as an important cofactor for several enzymes found within the vascular endothelium, which is deranged in sepsis. OBJECTIVE:We hypothesized that BH4 would improve capillary density and decrease inflammation within the intestinal microcirc...

journal_title：Clinical hemorheology and microcirculation

authors： Dumbarton TC,Maxan A,Farah N,Sharawy N,Zhou J,Nantais J,Lehmann C

更新日期：2017-01-01 00:00:00

abstract：:Disputes on the significance of cerebral lymphatic drainage pathways under physiological and pathophysiological conditions still exist. The purpose of this experiment is to investigate the influence of cerebral lymphatic blockage on cerebral blood flow and cortex somatosensory evoked potential. Wistar rat cerebral lym...

journal_title：Clinical hemorheology and microcirculation

authors： Xia ZL,Sun BL,Yang MF,Yuan H,Qiu PM,Chen YS

更新日期：2003-01-01 00:00:00