Infliximab-induced psoriasis in children with inflammatory bowel disease.

Abstract:

:Infliximab is frequently used to treat both inflammatory bowel disease (IBD) and psoriasis. We reviewed the medical records of 73 children with IBD receiving infliximab therapy and identified 6 (8%) cases of infliximab-induced psoriasis. Five (83%) had Crohn disease and 4 (67%) were girls. The psoriatic lesions appeared on the face (n = 5; 83%) and perineum (n = 1; 17%). A median of 13 doses were administered during a median duration of 21 months. All of the patients were continued on infliximab to maintain clinical remission of IBD. Educating children with IBD and their caregivers about this paradoxical phenomenon and periodic dermatology evaluation may promote patient care.

authors

Hiremath G,Duffy L,Leibowitz I

doi

10.1097/MPG.0b013e3181f3d9ab

subject

Has Abstract

pub_date

2011-02-01 00:00:00

pages

230-2

issue

2

eissn

0277-2116

issn

1536-4801

journal_volume

52

pub_type

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