Carbohydrate liquid crystals: synthesis and characterisation of the methyl-6-O-(n-acyl)-α-D-glucopyranosides.

abstract：:The indolic plant hormone, indole-3-acetic acid (IAA), mediated the transport of Mn2+ and other ions into small unilamellar vesicles prepared from soybean phosphatidylinositol (PI) and this process has been studied using 31P nuclear magnetic resonance spectroscopy (NMR). The rate of Mn2+ movement into PI vesicles is d...

journal_title：Chemistry and physics of lipids

authors： Jones GP,Misso NL,Paleg LG

更新日期：1992-04-01 00:00:00

abstract：:The chloroplast twin arginine translocation system transports highly folded precursor proteins across the thylakoid using the protonmotive force as its only energy source. Hcf106 and another thylakoid protein, cpTatC compose the precursor receptor complex. Hcf106 is predicted to contain a single amino terminal transme...

journal_title：Chemistry and physics of lipids

authors： Zhang L,Liu L,Maltsev S,Lorigan GA,Dabney-Smith C

更新日期：2013-10-01 00:00:00

abstract：:Bacteriophage M13 major coat protein is extensively used as a biophysical, biochemical, and molecular biology reference system for studying membrane proteins. The protein has several elements that control its position and orientation in a lipid bilayer. The N-terminus is dominated by the presence of negatively charged...

journal_title：Chemistry and physics of lipids

authors： Stopar D,Spruijt RB,Hemminga MA

更新日期：2006-06-01 00:00:00

abstract：:Divalent cation (Ca2+ and Mg2+) and hydrogen ion-induced fusions of small unilamellar phosphatidic acid vesicles were studied by the use of fluorescence fusion assay. These fusogenic ions also increased interfacial tension and reduced the surface dielectric constant of phosphatidic acid membranes as the ion concentrat...

journal_title：Chemistry and physics of lipids

authors： Ohki S,Zschörnig O

更新日期：1993-10-01 00:00:00

abstract：:The 220 MHz PMR spectra of 143 non-conjugated alkenoic and alkynoic acids and esters are correlated so as to provide a method for the structural analysis of such compounds in general. The spectral data are explained in terms of long-range deshielding of the double bonds, triple bonds, acid and ester groups in the mole...

journal_title：Chemistry and physics of lipids

authors： Frost DJ,Gunstone FD

更新日期：1975-09-01 00:00:00

abstract：:The stratum corneum (SC), the outermost layer of the mammalian skin, is the main skin barrier. Ceramides (CERs) as the major constituent of the SC lipid matrix are of particular interest. At the moment, 11 classes of CERs are identified, but the effect of each single ceramide species is still not known. Therefore in t...

journal_title：Chemistry and physics of lipids

authors： Kessner D,Brezesinski G,Funari SS,Dobner B,Neubert RH

更新日期：2010-01-01 00:00:00

abstract：:The antioxidant activity during storage at 30 degrees C of quercetin, myricetin and alpha-tocopherol in small unilamellar liposomes has been investigated. Myricetin was more effective than alpha-tocopherol as an antioxidant in liposomes under all conditions studied. At pH 5.4 with a concentration of 10(-2) mol/mol pho...

journal_title：Chemistry and physics of lipids

authors： Gordon MH,Roedig-Penman A

更新日期：1998-12-01 00:00:00

abstract：:The interaction of protoporphyrin IX (3,7,12,15-tetramethyl-8, 13-divinyl-2,18-porphyrine-dipropionic acid) (PPIX) with unilamellar dimyristoyl-L-alpha-phosphatidylcholine (DMPC) phospholipid vesicles has been studied by means of steady-state fluorescence quenching spectroscopy. The method of fluorescence-quenching-re...

journal_title：Chemistry and physics of lipids

authors： Kuszaj S,Kaszycki P,Wasylewski Z

更新日期：1996-09-30 00:00:00

abstract：:A comparative study of the polymorphism exhibited by the polymerizable, tubule-forming phospholipid 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3- phosphocholine (DC23PC) and its saturated analog 1,2-ditricosanoyl-sn-glycero-3-phosphocholine (DTPC) in aqueous suspension is reported. Differential scanning calorimetry (DSC...

journal_title：Chemistry and physics of lipids

authors： Burke TG,Rudolph AS,Price RR,Sheridan JP,Dalziel AW,Singh A,Schoen PE

更新日期：1988-10-01 00:00:00

abstract：:2-Hydroxypropane-1,3-bis(arsonic acid) after six successive reactions gives the arsinolipid 2-acyloxy-As, As'-bis[2,3-di(acyloxy)propyl]propane-1,3-diylbis(arsinic acid) in 20-40% overall yields. This arsinolipid is a non-isosteric analogue of the fully acylated cardiolipin. The R- and S-glycidol, used to create the b...

journal_title：Chemistry and physics of lipids

authors： Ioannou PV

更新日期：2002-08-01 00:00:00

abstract：:The growth of cationic lipid dioctadecyldimethylammonium bromide (DODAB) toward bilayer lipid membrane (BLM) by solution spreading on cleaved mica surface was studied by atomic force microscopy (AFM). Bilayer of DODAB was formed by exposing mica to a solution of DODAB in chloroform and subsequently immersing into pota...

journal_title：Chemistry and physics of lipids

authors： Wang L,Song Y,Han X,Zhang B,Wang E

更新日期：2003-04-01 00:00:00

abstract：:The X-ray crystal structure of 3 beta-benzoyloxy-6 alpha-chloro-5 alpha-cholest-7-ene (IV) was determined by the heavy atom method and refined to R = 0.063 (space group P21, a = 11.364, b = 11.089, c = 12.232, beta = 99.43 degrees, Z = 2). IV was previously shown to be an important intermediate in the acid-catalyzed i...

journal_title：Chemistry and physics of lipids

authors： Wilson DK,Wilson WK,Quiocho FA,Schroepfer GJ Jr

更新日期：1988-08-01 00:00:00

abstract：:Cardiolipins (CLs) are ancient and unusual dimeric phospholipids localized in the plasma membrane of bacteria and in the inner mitochondrial membrane of eukaryotes. In mitochondria, two types of asymmetries--trans-membrane and molecular--are essential determinants of CL functions. In this review, we describe CL-based ...

journal_title：Chemistry and physics of lipids

authors： Kagan VE,Chu CT,Tyurina YY,Cheikhi A,Bayir H

更新日期：2014-04-01 00:00:00

abstract：:Oxidised low density lipoprotein (LDL) was considered to be important in the pathogenesis of atherosclerosis, but the large clinical trials of antioxidants, including the first one using probucol (the PQRST Trial), failed to show benefit and have cast doubt on the importance of oxidised LDL. We have shown previously t...

journal_title：Chemistry and physics of lipids

authors： Ahmad F,Leake DS

更新日期：2018-07-01 00:00:00

abstract：:The chemical syntheses of a number of C27 15-oxygenated sterols and their derivatives have been pursued to permit evaluation of their activity in the inhibition of sterol biosynthesis in animal cells in culture. Described herein are chemical syntheses of 3 alpha-benzoyloxy-5 alpha-cholest-8(14)-en-15-one, 5 alpha-chol...

journal_title：Chemistry and physics of lipids

authors： Schroepfer GJ Jr,Parish EJ,Kandutsch AA

更新日期：1979-11-01 00:00:00

abstract：:Low-temperature molecular mobility and packing in biological tissues are important for their survival upon cryopreservation. Electron paramagnetic resonance (EPR) in its pulsed version of electron spin echo (ESE) allows studying stochastic librations of spin-labeled molecules, the type of motion which dominates at low...

journal_title：Chemistry and physics of lipids

authors： Golysheva EA,Dzuba SA

更新日期：2020-01-01 00:00:00

abstract：:Some thermodynamic and structural aspects of propranolol-DPPC liposomes interaction were investigated by DSC and X-ray diffraction: the lamellar arrangement of the lipid matrix remains intact even at high concentrations of the drug (until 1:1 drug/lipid molar ratio). However, the bilayer thickness increases significan...

journal_title：Chemistry and physics of lipids

authors： Albertini G,Donati C,Phadke RS,Ponzi Bossi MG,Rustichelli F

更新日期：1990-09-01 00:00:00

abstract：:Even though lysophospholipids have attracted much interest in recent years on account of their unique bioactivity, research related to lysophospholipids is usually hampered by problems associated with standard sample preparation and discrimination of regioisomers. Herein, we demonstrate a quick tin-chemistry-based syn...

journal_title：Chemistry and physics of lipids

authors： Furukawa T,Fuda H,Miyanaga S,Watanabe C,Chiba H,Hui SP

更新日期：2016-10-01 00:00:00

abstract：:Three novel polymerizable ether lipids, 1,2-O-bis[10(2',4'-hexadienoyloxy)decyl]-rac, 1,2-O-bis(10,12-tricosadiynyl)-rac, and (-)-2,3-O-bis(10,12-tricosadiynyl)-sn-glycero-1-phosphocholine, were synthesized from 3-O-benzyl-rac, 3-O-trityl-rac and (-)-1-O-trityl-sn-glycerol as starting materials, respectively. All the ...

journal_title：Chemistry and physics of lipids

authors： Lee YS,O'Brien DF

更新日期：1992-05-01 00:00:00

abstract：:The permeability of liposomes to water, glucose, Ca2+ and alkaline cations was monitored by recording the change in absorbance at 450 nm using a rapid reaction stopped-flow spectrophotometer. Liposomes were prepared with egg phosphatidylcholine and concentrations of dolichol ranging from 0.1% to 9% (w/w). Net permeabi...

journal_title：Chemistry and physics of lipids

authors： Boscoboinik DO,Feliz M,Disalvo EA,Belocopitow E

更新日期：1985-11-01 00:00:00

abstract：:Low density lipoprotein (LDL) particles exhibit extremely complex three-dimensional structural organization which is still not understood at the molecular level. The aim of this study was to provide the experimental evidence of a direct non-covalent interaction of the protein part with the lipid matrix. The approach w...

journal_title：Chemistry and physics of lipids

authors： Kveder M,Marinić Z,Krisko A,Vikić-Topić D,Pifat G

更新日期：2006-06-01 00:00:00

abstract：:Fourier transform infrared (FTIR) and time-resolved fluorescence spectroscopy have been employed to examine the structural dynamics of lipid fatty acyl chains and lipid/water interfacial region of a binary lipid mixture containing unsaturated phosphatidylethanolamine (PE) and diacylglycerol (DG). Infrared vibrational ...

journal_title：Chemistry and physics of lipids

authors： Chen SY,Cheng KH

更新日期：1990-12-01 00:00:00

abstract：:A known intermediate, (3 R, S; 5 R,S)-3,5-dimethyl-6-triphenylmethyloxyhexanal gave, in a Wittig reaction with 1-octyltriphenylphosphonium bromide and n-butyl lithium in anhydrous tetrahydrofuran, a mixture of olefininic compounds. Trityl deprotection and hydrogenation of the double bond afforded the (2 R, S; 4 R,S)-2...

journal_title：Chemistry and physics of lipids

authors： Wallace PA,Minnikin DE

更新日期：1996-08-19 00:00:00

abstract：:Racemic 1-O-(2-methyloctadecyl)-2-O-acetyl-glycero-3-phosphocholine, a branched chain PAF species, was prepared by chemical synthesis and investigated for biological activity on human blood platelets in vitro. The synthesis started from 2-O-benzylglycerol and 2-methyloctadecyl-1-methyl sulfonate and was accomplished i...

journal_title：Chemistry and physics of lipids

authors： Schmid B,Ostermann G,Kertscher HP

更新日期：1991-11-01 00:00:00

abstract：:A structural studies have been performed on new complex glycolipids extracted from hog gastric mucosa by 0.4 M sodium acetate in methanol-chloroform-water, and which were purified to homogeneity by DEAE-Sephadex and Florisil column chromatography and by preparative thin-layer chromatography in three solvent systems. F...

journal_title：Chemistry and physics of lipids

authors： Slomiany BL,Slomiany A

更新日期：1977-09-01 00:00:00

abstract：:Triolein, a triglyceride containing oleic acid as the only acid moiety in the glyceride molecules has been isothermally treated at 280, 300, and 325 degrees C in glass vials under nitrogen atmosphere. The products formed during the thermal treatment at each temperature have been analysed both by infrared spectrometry ...

journal_title：Chemistry and physics of lipids

authors： Christy AA,Xu Z,Harrington Pde B

更新日期：2009-03-01 00:00:00

abstract：:The influence of the temperature on the adsorption of monomeric and micellar solutions of the anionic surfactant sodium dodecyl sulfate (SDS) on phosphatidylcholine (PC) liposomes was investigated using the fluorescent probe 2-(p-toluidinyl)-naphthalene-6-sodium sulfonate (TNS). The number of adsorbed molecules was qu...

journal_title：Chemistry and physics of lipids

authors： Cócera M,López O,Estelrich J,Parra JL,de la Maza A

更新日期：2003-06-01 00:00:00

abstract：:Low density lipoprotein (LDL) cholesterol is known to be oxidized both in vitro and in vivo giving rise to oxygenated sterols. Conflicting results, however, have been reported concerning both the nature and the relative concentrations of these compounds in oxidized human LDL. We examined the extracts obtained from Cu(...

journal_title：Chemistry and physics of lipids

authors： Malavasi B,Rasetti MF,Roma P,Fogliatto R,Allevi P,Catapano AL,Galli G

更新日期：1992-10-01 00:00:00

abstract：:A convenient universal and fast mass spectrometrical method designed for the molecular species analysis of natural lipids is described. In contrast to the commonly employed procedures the method does not require chemical or enzymatic treatment and does not include chromatographic steps. The method relies on the recogn...

journal_title：Chemistry and physics of lipids

authors： Batrakov SG,Sadovskaya VL,Rozynov BV,Bergelson LD

更新日期：1983-11-01 00:00:00

abstract：:2',7'-Dichlorodihydrofluorescein diacetate (DCFH-DA) is commonly used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon. It has been suggested that DCFH-DA crosses the cell membrane, subsequently undergoing deacetylation by intracellula...

journal_title：Chemistry and physics of lipids

authors： Afri M,Frimer AA,Cohen Y

更新日期：2004-08-01 00:00:00