Posaconazole: clinical pharmacokinetics and drug interactions.

abstract：BACKGROUND:Oral follow-up therapy is problematic in moulds with reduced azole-susceptibility, such as azole-resistant Aspergillus fumigatus infection. Currently, only intravenous liposomal amphotericin B (L-AmB) is advocated by guidelines for the treatment of azole-resistant aspergillosis infections. Preclinical resear...

journal_title：Mycoses

authors： Schauwvlieghe AFAD,Buil JB,Verweij PE,Hoek RAS,Cornelissen JJ,Blijlevens NMA,Henriet SSV,Rijnders BJA,Brüggemann RJM

更新日期：2020-02-01 00:00:00

abstract：:Cryptococcus neoformans is an encapsulated yeast-like fungus that causes life-threatening infections, particularly in immunocompromised patients. The formation of brown pigment on many media described in the literature, such as that in Niger seed (Guizotia abyssinica) agar, has been used to identify C. neoformans. The...

journal_title：Mycoses

authors： Mseddi F,Sellami A,Sellami H,Cheikhrouhou F,Makni F,Ayadi A

更新日期：2011-07-01 00:00:00

abstract：:The aim of this study was to genotype Candida albicans strains isolated from patients with invasive and non-invasive deep-seated infections. For this purpose, 301 C. albicans isolates (81 invasive and 220 non-invasive) were genotyped by using specific PCR primers designed to span the transposable group I intron of the...

journal_title：Mycoses

authors： Karahan ZC,Güriz H,Ağirbaşli H,Balaban N,Göçmen JS,Aysev D,Akar N

更新日期：2004-12-01 00:00:00

abstract：:For the first time in the history of German mycology, a multicenter study for identification of dermatophytes, yeasts and molds was conducted under the auspices of the German Speaking Mycological Society and the German Dermatological Society. A total of 1,008 dermatological offices and dermatology hospitals as well as...

journal_title：Mycoses

authors： Tietz HJ

更新日期：2000-01-01 00:00:00

abstract：:This is a retrospective study on the superficial mycoses due to Trichophyton violaceum in the greater Athens area for the last 15 years - 1989-2003. During this period 104 patients were found to have an infection due to T. violaceum- an incidence rate of 0.75% of all dermatophytosis. Of the patients 59 were Greeks, 15...

journal_title：Mycoses

authors： Frangoulis E,Papadogeorgakis H,Athanasopoulou B,Katsambas A

更新日期：2005-11-01 00:00:00

abstract：:The aims of the study were to define the duration of candidaemia in newborn infants and to determine the incidence of persistent hospital-acquired candidaemia and its associated morbidity and mortality compared with non-persistent candidaemia. This retrospective study, included 56 neonates admitted to the neonatal int...

journal_title：Mycoses

authors： Levy I,Shalit I,Askenazi S,Klinger G,Sirota L,Linder N

更新日期：2006-05-01 00:00:00

abstract：:In this study, Fusarium species isolated from 29 patients with mycotic keratitis were identified and tested for their ability to produce mycotoxins. Members of the F. solani species complex (Fs complex) were the predominant species isolated, followed by F. verticillioides, F. dimerum, members of the F. oxysporum speci...

journal_title：Mycoses

authors： Naiker S,Odhav B

更新日期：2004-02-01 00:00:00

abstract：:This work presents the epidemiology of dermatomycoses and their etiological agents of people living in the Lódź region, Central Poland, over the years 1987-1996. The analysis involved subjects referred by physicians to three major mycological laboratories in Lódź (covering the entire mycological diagnostics of the Lód...

journal_title：Mycoses

authors： Seneczko F,Lupa S,Jeske J,Głowacka A,Ochecka-Szymańska A

更新日期：1999-01-01 00:00:00

abstract：:We report on a female patient who received a polychemotherapy because of an extensive pemphigus vulgaris. Under this therapy, the general condition of the patient worsened. Noncharacteristic symptoms, such as dyspnoea and tachycardia occurred. In spite of comprehensive, also invasive diagnostics, pulmonary foci demons...

journal_title：Mycoses

authors： Sima D,Tietz HJ,Reisshauer H,Buchholtz I,Schulze P,Meyer R

更新日期：1994-11-01 00:00:00

abstract：:Due to the Fourier-Transform Infrared Spectroscopy (FT-IR) of strain specific traits demonstrated to be a suitable and efficient method for diagnostic and epidemiological determinations for the yeasts Candida albicans, Exophiala dermatitidis and the chlorophylless algae of the genus Prototheca. FT-IR leads in a rapid ...

journal_title：Mycoses

authors： Schmalreck AF,Tränkle P,Vanca E,Blaschke-Hellmessen R

更新日期：1998-01-01 00:00:00

abstract：:This study sought to determine the prevalence of skin infections and their causative agents in the Libyan population. Samples were collected from 2224 patients attending the Dermatology Clinics of the Tripoli Medical Centre (TMC) between August 1997 and December 1999 and were submitted to a mycology laboratory for ana...

journal_title：Mycoses

authors： Ellabib MS,Khalifa Z,Kavanagh K

更新日期：2002-04-01 00:00:00

abstract：:Onychomycosis in HIV-infected patients has a prevalence of 20-44% and is more frequently seen with CD4(+) T cell counts ≤450 cel μl(-1). There are case reports of improvement in onychomycosis after initiation of combined antiretroviral therapy (cART), but there are no prospective studies that prove the existence and f...

journal_title：Mycoses

authors： Ruíz-López P,Moreno-Coutiño G,Fernández-Martínez R,Espinoza-Hernández J,Rodríguez-Zulueta P,Reyes-Terán G

更新日期：2015-09-01 00:00:00

abstract：:Repeated and prolonged use of fluconazole in treating candidosis leads to drug resistance. The aim of this study was to confirm the relationship between T916C (Y257H) mutation in Candida albicans ERG11 and fluconazole resistance. We replaced one copy of ERG11 with ERG11 containing the T916C mutation in C. albicans CAI...

journal_title：Mycoses

authors： Zhao J,Xu Y,Li C

更新日期：2013-05-01 00:00:00

abstract：:To describe the epidemiology of invasive Candida infection in a tertiary care paediatric hospital. Prospective single-centre survey on all Candida strains isolated from normally sterile fluids and urines in the period 2005-2015 . A total of 299 ICI were documented in 262 patients. Urinary tract infection represented t...

journal_title：Mycoses

authors： Mesini A,Bandettini R,Caviglia I,Fioredda F,Amoroso L,Faraci M,Mattioli G,Piaggio G,Risso FM,Moscatelli A,Loy A,Castagnola E

更新日期：2017-02-01 00:00:00

abstract：:During the last decade cryptococcoses were most frequently diagnosed in AIDS patients, where serologically high amounts of glucoronoxylomannan (GXM) were detectable. Disseminated cryptococcoses without cryptococcal antigen detection is unusual. Between August and October 1998 disseminated cryptococcoses were diagnosed...

journal_title：Mycoses

authors： Tintelnot K,Adler S,Bergmann F,Schönherr K,Seibold M

更新日期：2000-01-01 00:00:00

abstract：:Many studies have described the adherence of Candida albicans to epithelial cells but little is known about Candida parapsilosis adhesion and its role in host cell surface recognition. This study was designed to evaluate the correlation between the adherence of 20 C. albicans and 12 C. parapsilosis strains to human bu...

journal_title：Mycoses

authors： Lima-Neto RG,Beltrão EI,Oliveira PC,Neves RP

更新日期：2011-01-01 00:00:00

abstract：:A case of tinea capitis due to Microsporum gypseum in an adult is described. An otherwise healthy 69-year-old woman presented two large patches of slightly erythematous scaling alopecia localized on the vertex and on the left parietal region of the scalp. The only subjective sign was itching. A mycological culture was...

journal_title：Mycoses

authors： Offidani A,Simoncini C,Arzeni D,Cellini A,Amerio P,Scalise G

更新日期：1998-05-01 00:00:00

abstract：INTRODUCTION:It was shown previously that dermatophytes can markedly be inhibited by a photochemical treatment with curcumin. This kind of photo-inactivation needs to be improved, however, because curcumin is poorly water-soluble. Therefore, a new water-soluble γ-cyclodextrin formulation of curcuminoids was tested for ...

journal_title：Mycoses

authors： Brasch J,Beck-Jendroschek V,Walther G,Rubbel D

更新日期：2020-04-01 00:00:00

abstract：:Fusarium infections are increasingly being encountered in immunocompromised patients. Fusarium solani accounts for nearly half of these infections. A specific nested PCR (nPCR) assay has been developed by using DNA isolated from several Fusarium species and other common fungi. Furthermore, DNA samples isolated from br...

journal_title：Mycoses

authors： Ahmad S,Khan ZU,Theyyathel AM

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Pulmonary cryptococcosis (PC) is not considered an rare, opportunistic infection anymore. The immunocompetent population accounts for an increasing proportion of the morbidity. OBJECTIVE:This study investigated the clinical characteristics of PC patients spanning 20 years, in a referral centre of China. PA...

journal_title：Mycoses

authors： Hou X,Kou L,Han X,Zhu R,Song L,Liu T

更新日期：2019-10-01 00:00:00

abstract：:Regulation of morphogenesis through the production of chemical signalling molecules such as isoamyl alcohol, 2-phenylethyl alcohol, 1-dodecanol, E-nerolidol and farnesol is reported in Candida albicans. The present study focuses on the effect of ethyl alcohol on C. albicans dimorphism and biofilm development. Ethyl al...

journal_title：Mycoses

authors： Chauhan NM,Raut JS,Karuppayil SM

更新日期：2011-11-01 00:00:00

abstract：:Zygomycoses are very rare invasive fungal infections (IFI). They primarily occur in the immunocompromised patients and are associated with a high mortality. During the last years, a rising incidence of zygomycosis in patients undergoing allogeneic haematopoietic stem cell transplantation (HSCT) has been reported, whic...

journal_title：Mycoses

authors： Glöckner A,Vehreschild JJ,Cornely OA

更新日期：2007-01-01 00:00:00

abstract：:Disseminated histoplasmosis (DH) is the most current revelation mode of AIDS in French Guiana. We describe the clinical and paraclinical presentation of DH, diagnostic tools, evolution and factors associated with 1-year mortality in HIV-infected patients from western French Guiana. Microbiologically proven AIDS-relate...

journal_title：Mycoses

authors： Putot A,Perrin S,Jolivet A,Vantilcke V

更新日期：2015-03-01 00:00:00

abstract：:One atypical isolate of the pathogenic yeast Candida albicans was isolated from an Italian patient with vulvovaginitis. The strain, germ tube positive and chlamydospore-negative showed white-thin turquoise colonies on Candida ID 2 medium. The yeast was identified as Candida africana by using morphological and biochemi...

journal_title：Mycoses

authors： Romeo O,Criseo G

更新日期：2009-09-01 00:00:00

abstract：:Four commercially available in vitro test systems (Candifast, E-test, Mycototal and spiral-gradient end point method), agar diffusion with 25-micrograms fluconazole paper test discs and 15-micrograms test tablets and agar dilution were compared with the microbroth dilution method for fluconazole susceptibility testing...

journal_title：Mycoses

authors： Schmalreck AF,Kottmann I,Reiser A,Ruffer U,Scharr E,Vanca E

更新日期：1995-09-01 00:00:00

abstract：:Despite several chemotherapeutic and preventative advances, opportunistic fungal infections remain common unintended consequences of cancer treatment. Currently, cancer patients spend most of their time between treatments at home, where they can inadvertently come across potential hazards from environmental and food s...

journal_title：Mycoses

authors： Ariza-Heredia EJ,Kontoyiannis DP

更新日期：2014-06-01 00:00:00

abstract：:Itraconazole is a lipophilic triazole antifungal with a broad spectrum of activity. Most of the important fungal pathogens respond to itraconazole concentrations of 100 ng/ml. Therefore, itraconazole is suitable for treatment of a variety of systemic mycoses, as aspergillosis, cryptococcosis, candidosis as well as non...

journal_title：Mycoses

authors： Cauwenbergh G

更新日期：1994-01-01 00:00:00

abstract：:Pomegranate is a wonderful fruit from the paradise which contains a wide variety of precious phytochemical compounds applicable in the fields of therapeutics and health care. Candida albicans is the most common etiological agent for many clinical mycoses which could lead to human and animal death. Determination of the...

journal_title：Mycoses

authors： Tayel AA,El-Tras WF

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Cryptococcal meningitis accounts for 15% of all AIDS mortality globally. Most cases in low- and middle-income countries are treated with fluconazole monotherapy, which is associated with a high mortality. New available therapies are needed. Short-course amphotericin B has been shown to be a safe and efficien...

journal_title：Mycoses

authors： Katende A,Mbwanji G,Faini D,Nyuri A,Kalinjuma AV,Mnzava D,Hullsiek KH,Rhein J,Weisser M,Meya DB,Boulware DR,Letang E,KIULARCO Study Group.

更新日期：2019-12-01 00:00:00

abstract：:Mycetoma is a chronic granulomatous, subcutaneous disease endemic in tropical and subtropical countries. It is currently a health problem in rural areas of Africa, Asia and South America. Nine cases of mycetoma were analysed in a retrospective study. All isolates were identified by morphological features. The level of...

journal_title：Mycoses

authors： Rojas OC,León-Cachón RB,Moreno-Treviño M,González GM

更新日期：2017-02-01 00:00:00