Correlation of MRI sequences to assess progressive glioblastoma multiforme treated with bevacizumab.

abstract：:Although their neurocognitive performance is one of the major concerns of patients with high-grade gliomas (HGG) and although neurocognitive deficits have been described to be associated with negative outcome, neurocognitive rehabilitation is usually not integrated into the routine care of patients with malignant glio...

journal_title：Journal of neuro-oncology

authors： Hassler MR,Elandt K,Preusser M,Lehrner J,Binder P,Dieckmann K,Rottenfusser A,Marosi C

更新日期：2010-03-01 00:00:00

abstract：:The value of perfusion and diffusion-weighted MRI in differentiating histological subtypes according to the 2007 WHO glioma classification scheme (i.e. astrocytoma vs. oligodendroglioma) and genetic subtypes according to the 2016 WHO reclassification (e.g. 1p/19q co-deletion and IDH1 mutation status) in WHO grade II a...

journal_title：Journal of neuro-oncology

authors： Leu K,Ott GA,Lai A,Nghiemphu PL,Pope WB,Yong WH,Liau LM,Cloughesy TF,Ellingson BM

更新日期：2017-08-01 00:00:00

abstract：:Atypical teratoid/rhabdoid tumors (AT/RTs) are rare, malignant brain tumors which occur almost exclusively in infants and young children. There have been only 17 cases of AT/RT in adults reported in the medical literature and the rarity of this tumor makes the diagnosis in adults difficult. We describe a case of an AT...

journal_title：Journal of neuro-oncology

authors： Zarovnaya EL,Pallatroni HF,Hug EB,Ball PA,Cromwell LD,Pipas JM,Fadul CE,Meyer LP,Park JP,Biegel JA,Perry A,Rhodes CH

更新日期：2007-08-01 00:00:00

abstract：:The new anticancer agent Taxol appears to potentiate the effects of radiation on brain tumor cell lines in vitro and was recently evaluated by our group as a radiosensitizer in a phase I study for primary brain tumors. In that study, we administered Taxol as a three-hour IV infusion repeated every week for six weeks a...

journal_title：Journal of neuro-oncology

authors： Wehbe T,Glantz M,Choy H,Glantz L,Cortez S,Akerley W 3rd,Mills P,Cole B

更新日期：1998-09-01 00:00:00

abstract：:We proposed to identify the efficacy of an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) using whole brain radiotherapy (WBRT)/stereotactic radiosurgery (SRS)/surgery in brain metastases from patients with non-small cell lung cancer (NSCLC) and clarify the association between treatment outcom...

journal_title：Journal of neuro-oncology

authors： Cai L,Zhu JF,Zhang XW,Lin SX,Su XD,Lin P,Chen K,Zhang LJ

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Despite aspirations to achieve equality in healthcare we know that socioeconomic differences exist and may affect treatment and patient outcome, also in serious diseases such as cancer. We investigated disparities in neurosurgical care and outcome for patients with low-grade glioma (LGG). METHODS:In this na...

journal_title：Journal of neuro-oncology

authors： Carstam L,Rydén I,Gulati S,Rydenhag B,Henriksson R,Salvesen Ø,Smits A,Jakola AS

更新日期：2020-01-01 00:00:00

abstract：:A list of active investigative brain tumor protocols in North America is presented. The fact that there are 138 protocols (and certainly some have been missed) indicates the diversity and intensity of research into this difficult problem. The geographic diversity of institutions involved in brain tumor clinical trials...

journal_title：Journal of neuro-oncology

authors： Bernstein M,Rutka J

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to compare three-dimensional conformal radiotherapy (3D-CRT) with intensity-modulated radiotherapy (IMRT) for the treatment of glioblastoma. MATERIALS AND METHODS:Retrospective study of 220 patients with glioblastoma, treated with 3D-CRT or IMRT, with or without surgery. Dosimetric para...

journal_title：Journal of neuro-oncology

authors： Thibouw D,Truc G,Bertaut A,Chevalier C,Aubignac L,Mirjolet C

更新日期：2018-04-01 00:00:00

abstract：:Extraskeletal myxoid chondrosarcoma is a rare tumor with less than 100 cases reported in the literature. The prevalence of anti-Hu positive myxoid chondrosarcoma-associated paraneoplastic subacute cerebellar degeneration is exceedingly rare. We present a report of a patient with confirmed myxoid chondrosarcoma-associa...

journal_title：Journal of neuro-oncology

authors： Hoosien M,Vredenburgh J,Lanfranco J,Ochoa R,Robinson P,Martinez R,Singer C,Silva O

更新日期：2011-01-01 00:00:00

abstract：:High grade astrocytomas remain incurable even though these tumors often appear localized on modern imaging studies, rarely metastasize to systemic sites, and can be aggressively treated with surgery and radiation therapy. Recent data suggest that the dissemination of astrocytoma cells along white matter tracts to dist...

journal_title：Journal of neuro-oncology

authors： Geer CP,Grossman SA

更新日期：1997-05-01 00:00:00

abstract：:We observed three neoplasms with completely different histologies: malignant fibrous histiocytoma (MFH), atypical meningioma (AM), and glioblastoma (GB), developing in a patient with Li-Fraumeni syndrome. By using a combined molecular approach we performed molecular characterization of all three tumours. Data obtained...

journal_title：Journal of neuro-oncology

authors： Rieske P,Zakrzewska M,Biernat W,Bartkowiak J,Zimmermann A,Liberski PP

更新日期：2005-01-01 00:00:00

abstract：:Mucus-secreting adenomas or acinar adenoma of the choroid plexus are very rare. We report the case of a 79-year-old male with a 3-year history of occipital headaches with vomiting, ataxia and cerebellar signs. He was first seen due to difficulty while walking. He was admitted to the hospital with significant tumor exp...

journal_title：Journal of neuro-oncology

authors： Rembao-Bojórquez D,Vega R,Bermúdez-Maldonado L,Gutiérrez R,Salinas C,Tena-Suck M

更新日期：2007-06-01 00:00:00

abstract：INTRODUCTION:It is useful to know the molecular subtype of lower-grade gliomas (LGG) when deciding on a treatment strategy. This study aims to diagnose this preoperatively. METHODS:A deep learning model was developed to predict the 3-group molecular subtype using multimodal data including magnetic resonance imaging (M...

journal_title：Journal of neuro-oncology

authors： Matsui Y,Maruyama T,Nitta M,Saito T,Tsuzuki S,Tamura M,Kusuda K,Fukuya Y,Asano H,Kawamata T,Masamune K,Muragaki Y

更新日期：2020-01-01 00:00:00

abstract：:Human melanoma proteoglycan (HMP), a melanoma-associated antigen, is expressed in both human melanomas and gliomas. We used HMP-specific monoclonal antibody (mAb) VT68.2 to investigate whether murine GL261 cerebral gliomas express the HMP homologue AN2 and to determine whether AN2 could be targeted for selective deliv...

journal_title：Journal of neuro-oncology

authors： Paul AK,Ciesielski MJ,Sajjad M,Wang X,Ferrone S,Abdel-Nabi H,Fenstermaker RA

更新日期：2009-08-01 00:00:00

abstract：:Two main varieties of recognition disorders are distinguished in neuropsychology: agnosias and semantic disorders. The term agnosias is generally used to denote recognition defects limited to a single perceptual modality (which is itself apparently intact), whereas the term semantic disorders is used to denote recogni...

journal_title：Journal of neuro-oncology

authors： Gainotti G

更新日期：2012-06-01 00:00:00

abstract：:ATP-binding cassette transporters (ABC transporters) regulate traffic of multiple compounds, including chemotherapeutic agents, through biological membranes. They are expressed by multiple cell types and have been implicated in the drug resistance of some cancer cells. Despite significant research in ABC transporters ...

journal_title：Journal of neuro-oncology

authors： Dréan A,Rosenberg S,Lejeune FX,Goli L,Nadaradjane AA,Guehennec J,Schmitt C,Verreault M,Bielle F,Mokhtari K,Sanson M,Carpentier A,Delattre JY,Idbaih A

更新日期：2018-07-01 00:00:00

abstract：:Extra-axial cerebellopontine angle (CPA) tumors account for approximately 10% of all brain neoplasms in adults. Vestibular schwannomas are the most common, followed by meningiomas. Gliomas in the CPA are rare and quite often are the exophytic extension of primary brain stem or cerebellar tumors. We describe a pilocyti...

journal_title：Journal of neuro-oncology

authors： Francesco F,Maurizio I,Stefano C,Marina S,Ugo S,Massimo S

更新日期：2010-04-01 00:00:00

abstract：:While stereotactic radiosurgery (SRS) has been shown effective in the management of brain metastases, small brain metastases (≤10 mm) can pose unique challenges. Our aim was to investigate the efficacy of SRS in the treatment of small brain metastases, as well as elucidate clinically relevant factors impacting local f...

journal_title：Journal of neuro-oncology

authors： Trifiletti DM,Hill C,Cohen-Inbar O,Xu Z,Sheehan JP

更新日期：2017-09-01 00:00:00

abstract：:Diffuse invasion of the brain by tumor cells is a hallmark of human glioblastomas and a major cause for the poor prognosis of these tumors. This phenomenon is only partially reproduced by rodent models of gliomas that display a very high rate of proliferation and limited cell migration. We have analyzed the developmen...

journal_title：Journal of neuro-oncology

authors： Guillamo JS,Lisovoski F,Christov C,Le Guérinel C,Defer GL,Peschanski M,Lefrançois T

更新日期：2001-05-01 00:00:00

abstract：:Most tumors, including gliomas, are resistant to tumor necrosis factor (TNF) cytotoxicity unless protein or RNA synthesis is inhibited. We investigated the effects of the combined use of TNF-alpha and cisplatin (CDDP) on cultured malignant glioma cells, T98G, U373MG, A172, and U87MG. All glioma cell lines were sensiti...

journal_title：Journal of neuro-oncology

authors： Duan L,Aoyagi M,Tamaki M,Nakagawa K,Nagashima G,Nagasaka Y,Ohno K,Yamamoto K,Hirakawa K

更新日期：2001-03-01 00:00:00

abstract：:We report a single-center experience of 16 immunocompetent patients diagnosed with primary central nervous system lymphoma and treated with monochemotherapy with high-dose methotrexate (MTX) and deferred radiotherapy. MTX was given at a dose of 8.0 g/m2 for induction and at a dose of 3.5-8.0 g/m2 for maintenance. Ther...

journal_title：Journal of neuro-oncology

authors： Yang SH,Lee KS,Kim IS,Hong JT,Sung JH,Son BC,Lee SW,Hong YK

更新日期：2009-03-01 00:00:00

abstract：:Purpose of this study was to determine the effect of waiting time for radiotherapy on overall survival of patients with glioblastoma treated in the EORTC-NCIC trial at 18 centers in France. A total of 400 adult patients with glioblastoma who were treated between January 1, 2006 and December 31, 2006 were included. The...

journal_title：Journal of neuro-oncology

authors： Noel G,Huchet A,Feuvret L,Maire JP,Verrelle P,Le Rhun E,Aumont M,Thillays F,Sunyach MP,Henzen C,Missohou F,de Crevoisier R,Bondiau PY,Collin P,Durando X,Truc G,Kerr C,Bernier V,Clavier JB,Atlani D,D'Hombres A,Vi

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:Chondroblastoma (CB) in the spine is extremely rare and there is little published information regarding this subject. We attempt to explore the clinical features of spinal CB and address the importance of total resection, especially total en bloc spondylectomy (TES) for the treatment of spinal CB. METHODS:Clin...

journal_title：Journal of neuro-oncology

authors： Jia Q,Liu C,Yang J,Ji Y,Wei H,Liu T,Yang X,Yang C,Xiao J

更新日期：2018-10-01 00:00:00

abstract：:Two distinct mechanisms, vasculogenesis and angiogenesis implement the formation of the vascular network in the embryo. Vasculogenesis gives rise to the heart and the first primitive vascular plexus inside the embryo and in its surrounding membranes, as the yolk sac circulation. Angiogenesis is responsible for the rem...

journal_title：Journal of neuro-oncology

authors： Patan S

更新日期：2000-10-01 00:00:00

abstract：:Children with a brain tumor (BT) are at risk for a number of physical and cognitive problems that may lower their health-related quality of life (HRQoL). Executive functioning (EF) and intellectual ability are hypothesized to associate with HRQoL and deficits in these areas may be amenable to interventions. This study...

journal_title：Journal of neuro-oncology

authors： Netson KL,Ashford JM,Skinner T,Carty L,Wu S,Merchant TE,Conklin HM

更新日期：2016-06-01 00:00:00

abstract：:We report a 13-month-old boy with diencephalic syndrome (DS) due to an optico-hypothalamic juvenile pilocytic astrocytoma (JPA). Massive neuroaxis dissemination was identified at diagnosis. He received 6 courses of combined conventional-dose chemotherapy consisting of carboplatin (CBDCA), etoposide (VP-16), and cyclop...

journal_title：Journal of neuro-oncology

authors： Kageji T,Nagahiro S,Horiguchi H,Watanabe T,Suzuya H,Okamoto Y,Kuroda Y

更新日期：2003-05-01 00:00:00

abstract：:Despite similar morphological aspects, anaplastic oligodendroglial tumors (AOTs) form a heterogeneous clinical subgroup of gliomas. The chromosome arms 1p/19q codeletion has been shown to be a relevant biomarker in AOTs and to be perfectly exclusive from EGFR amplification in gliomas. To identify new genomic regions a...

journal_title：Journal of neuro-oncology

authors： Idbaih A,Dalmasso C,Kouwenhoven M,Jeuken J,Carpentier C,Gorlia T,Kros JM,French P,Teepen J,Broët P,Delattre O,Mokhtari K,Sanson M,Delattre JY,van den Bent M,Hoang-Xuan K

更新日期：2011-06-01 00:00:00

abstract：:'Benign' brain tumors are a heterogeneous group of primary neoplasms representing 40% of primary brain tumors. Amongst neuroepithelial tumors, astrocytic neoplasms predominate, followed by oligodendroglial and mixed glial and glial-neuronal neoplasms. Less common are tumors of the ependyma, choroid plexus and neuroepi...

journal_title：Journal of neuro-oncology

authors： Piepmeier J,Baehring JM

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Central neurocytoma is recognized as a indolent intraventricular tumor arising from the ependyma around the foramen of Monro and anterior part of the lateral ventricles, and well demarcated from the brain parenchyma. Surgical removal can be curative without postoperative therapy. However, malig...

journal_title：Journal of neuro-oncology

authors： Ogawa Y,Sugawara T,Seki H,Sakuma T

更新日期：2006-09-01 00:00:00

abstract：OBJECT:Subependymomas are rare ependymal neoplasms. To date, a large clinicopathologic study of these benign neoplasms treated with modern neurosurgical techniques has not been reported. METHODS:Eighty-three cases of subependymoma were retrieved from the files of the Armed Forces Institute of Pathology. Clinicopatholo...

journal_title：Journal of neuro-oncology

authors： Rushing EJ,Cooper PB,Quezado M,Begnami M,Crespo A,Smirniotopoulos JG,Ecklund J,Olsen C,Santi M

更新日期：2007-12-01 00:00:00