Abstract:
OBJECTIVE:To investigate the long-term effect of expanded cardiac rehabilitation on a composite end-point, consisting of cardiovascular death, myocardial infarction or readmission for cardiovascular disease, in patients with coronary artery disease. DESIGN:Single-centre prospective randomized controlled trial. SETTING:University hospital. SUBJECTS:Two hundred and twenty-four patients with acute myocardial infarction or undergoing coronary artery by-pass grafting. INTERVENTION:Patients were randomized to expanded cardiac rehabilitation (a one-year stress management programme, increased physical training, staying at a 'patient hotel' for five days after the event, and cooking sessions), or to standard cardiac rehabilitation. MAIN MEASURES:Data on cardiovascular death, myocardial infarction, readmission for cardiovascular disease and days at hospital for cardiovascular reasons were obtained from national registries of the Swedish National Board of Health and Welfare. RESULTS:The primary end-point occurred in 121 patients altogether (54%). The number of cardiovascular events were reduced in the expanded rehabilitation group compared with the standard cardiac rehabilitation (53 patients (47.7%) versus 68 patients (60.2%); hazard ratio 0.69; P =0.049). This was mainly because of a reduction of myocardial infarctions in the expanded rehabilitation group. During the five years 12 patients (10.8%) versus 23 patients (20.3%); hazard ratio 0.47; P =0.047 had a myocardial infarction. Days at hospital for cardiovascular reasons were significantly reduced in patients who received expanded cardiac rehabilitation (median 6 days) compared with standard cardiac rehabilitation (median 10 days; P =0.02). CONCLUSION:Expanded cardiac rehabilitation after acute myocardial infarction or coronary artery bypass grafting reduces cardiovascular morbidity and days at hospital for cardiovascular reasons.
journal_name
Clin Rehabiljournal_title
Clinical rehabilitationauthors
Plüss CE,Billing E,Held C,Henriksson P,Kiessling A,Karlsson MR,Wallen HNdoi
10.1177/0269215510376006subject
Has Abstractpub_date
2011-01-01 00:00:00pages
79-87issue
1eissn
0269-2155issn
1477-0873pii
0269215510376006journal_volume
25pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:To systematically examine the research literature on the effectiveness of constraint-induced movement therapy on improving arm function in children with cerebral palsy, and to assess the association between the study effect size and the characteristics of the patients and intervention protocol. DATA SOURCES:...
journal_title:Clinical rehabilitation
pub_type: 杂志文章,meta分析,评审
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更新日期:2014-10-01 00:00:00
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更新日期:2003-05-01 00:00:00
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更新日期:2014-06-01 00:00:00