Effectiveness of constraint-induced movement therapy on upper-extremity function in children with cerebral palsy: a systematic review and meta-analysis of randomized controlled trials.

Abstract:

OBJECTIVE:To systematically examine the research literature on the effectiveness of constraint-induced movement therapy on improving arm function in children with cerebral palsy, and to assess the association between the study effect size and the characteristics of the patients and intervention protocol. DATA SOURCES:A systematic literature search was conducted in PubMed, PsycINFO, Cochrane, CINAHL, Web of Science, and TRIP Database up to May 2014. REVIEW METHODS:Studies employing randomized controlled trial design, children with cerebral palsy, comparing constraint-induced movement therapy with another intervention with a focus on arm function, and upper-extremity measures were included in this review. Methodological quality was evaluated using the Physiotherapy Evidence-based Database (PEDro) scale. RESULTS:The literature search resulted in 27 randomized controlled trial studies with good methodological quality that compared constraint-induced movement therapy with other intervention therapy. Overall, constraint-induced movement therapy provided a medium beneficial effect (d = 0.546; p < 0.001) when compared with conventional therapy. For the subgroup analyses, presence of a dose-equivalent comparison group, intervention location, and time of follow-up were significant factors. Studies examining constraint-induced movement therapy effect without a dose-equivalent comparison group showed a large effect in children with cerebral palsy, but studies with a dose-equivalent group only showed a small effect. Children who received home-based constraint-induced movement therapy had a better improvement in arm function than those who received constraint-induced movement therapy elsewhere. CONCLUSION:The research literature supports constraint-induced movement therapy as an effective intervention to improve arm function in children with cerebral palsy.

journal_name

Clin Rehabil

journal_title

Clinical rehabilitation

authors

Chen YP,Pope S,Tyler D,Warren GL

doi

10.1177/0269215514544982

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

939-53

issue

10

eissn

0269-2155

issn

1477-0873

pii

0269215514544982

journal_volume

28

pub_type

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