Inappropriate oral formulations and information in paediatric trials.

abstract：OBJECTIVE:To compare a comprehensive lifestyle intervention for overweight children performed in groups of families with a conventional single-family treatment. Two-year follow-up data on anthropometric and psychological outcome are presented. DESIGN:Overweight and obese children aged 6-12 years with body mass index (...

journal_title：Archives of disease in childhood

authors： Kokkvoll A,Grimsgaard S,Steinsbekk S,Flægstad T,Njølstad I

更新日期：2015-05-01 00:00:00

abstract：:Ten patients with biotinidase deficiency were studied. Clinical findings at presentation varied with dermatological signs (dermatitis and alopecia), neurological abnormalities (fits, hypotonia, and ataxia), and recurrent infections being the most common features, although none of these occurred in every case. Biochemi...

journal_title：Archives of disease in childhood

authors： Wastell HJ,Bartlett K,Dale G,Shein A

更新日期：1988-10-01 00:00:00

abstract：:An adult woman with pseudopseudohypoparathyroidism had a child with normal calcium and parathyroid hormone concentrations and cyclic AMP response to injected parathyroid hormone in infancy. By 2.5 years he had features of pseudohypoparathyroidism with raised parathyroid hormone and 'flat' cyclic AMP response. This is ...

journal_title：Archives of disease in childhood

authors： Barr DG,Stirling HF,Darling JA

更新日期：1994-04-01 00:00:00

abstract：:Gross neuropathy consequent upon selective malabsorption of vitamin B12 was diagnosed in a 6 year old Bangladeshi girl brought to Great Britain for further investigation of an unexplained illness of three years' duration. The initial peripheral blood count was normal. Treatment with vitamin B12 has led to substantial ...

journal_title：Archives of disease in childhood

authors： Conway SP,Gillies DR,Littlewood JM

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:Our current understanding regarding the aetiology of infantile acute liver failure largely derives from studies conducted by regional liver units. This may introduce selection bias and therefore not provide a true reflection of the wider population. METHODS:Every coagulation screen with a prothrombin time ≥...

journal_title：Archives of disease in childhood

authors： Wands D,Tayler R,Kelly D,Pinto F,Simpson JH,Hansen R

更新日期：2020-08-01 00:00:00

abstract：:Over a period of 30 months, umbilical artery catheters were inserted in 229 infants. The main complications were haemorrhage, infection, and obstruction of a blood vessel. The incidence of infection was not affected by the use of prophylactic antibiotics. Vascular obstruction was more common in small infants, and in t...

journal_title：Archives of disease in childhood

authors： van Vliet PK,Gupta JM

更新日期：1973-04-01 00:00:00

abstract：BACKGROUND:Children receiving chemotherapy for acute lymphoblastic leukaemia (ALL) may be susceptible to skeletal morbidity. AIM:To determine the incidence and risk factors for skeletal morbidity in ALL children. PATIENTS AND METHODS:The medical records of all (n=186, boys=110) children presenting to a single centre ...

journal_title：Archives of disease in childhood

authors： Elmantaser M,Stewart G,Young D,Duncan R,Gibson B,Ahmed SF

更新日期：2010-10-01 00:00:00

abstract：:Diseases causing high mortality in children under 5 years of age in resource limited settings (RLS) could be treated if children in these countries had access to existing medicines. It took 30 years before the WHO Essential Medicines List (EML) considered the issue of medicines for children, with the first EML for chi...

journal_title：Archives of disease in childhood

authors： Hoppu K,Sri Ranganathan S,Dodoo AN

更新日期：2011-08-01 00:00:00

abstract：:An 11 year old girl developed progressive upper gastrointestinal ulceration and recurrent episodes of intravenous catheter associated polymicrobial septicaemia. Evaluation failed to establish a cause. After exclusion of the parents and careful surveillance of the patient she improved, supporting the diagnosis of suspe...

journal_title：Archives of disease in childhood

authors： Rubin LG,Angelides A,Davidson M,Lanzkowsky P

更新日期：1986-09-01 00:00:00

abstract：:We have measured total work of breathing before and after the inhalation of water, salbutamol, and ipratropium bromide, given as nebulised solutions, in 39 studies on 25 infants with acute, severe bronchiolitis. Twenty minutes after nebulised water, mean work of breathing per minute was increased by 4% and work per li...

journal_title：Archives of disease in childhood

authors： Stokes GM,Milner AD,Hodges IG,Henry RL,Elphick MC

更新日期：1983-04-01 00:00:00

abstract：:This study examines the relationship between medical and functional severity of disability and levels of self esteem and self concept in 79 young people with spina bifida. Greater feelings of global self worth and of self esteem in physical appearance were associated with greater severity of disability. This was only ...

journal_title：Archives of disease in childhood

authors： Minchom PE,Ellis NC,Appleton PL,Lawson V,Böll V,Jones P,Elliott CE

更新日期：1995-07-01 00:00:00

abstract：:Standing height, sitting height, armspan, subischial leg length, head circumference, and growth hormone-insulin-like growth factor I (IGF-I) axis were determined in 86 patients with osteogenesis imperfecta. The aim of this study was to determine standing height and body proportions and their variability among osteogen...

journal_title：Archives of disease in childhood

authors： Lund AM,Müller J,Skovby F

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVES:The amount of adipose tissue influences pubertal development and fertility in girls. A candidate for mediating this is the hormone leptin, derived from adipocytes. This work was carried out to determine whether the leptin concentration in serum is regulated during pubertal development. SUBJECTS AND METHODS:...

journal_title：Archives of disease in childhood

authors： Carlsson B,Ankarberg C,Rosberg S,Norjavaara E,Albertsson-Wikland K,Carlsson LM

更新日期：1997-11-01 00:00:00

abstract：:Three babies said to have had 'meconium stained liquor' were subsequently found never to have passed meconium. The green discoloured liquor was the result of bilious vomiting in utero secondary to intestinal obstruction. ...

journal_title：Archives of disease in childhood

authors： Griffiths DM,Burge DM

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVE:The development, delivery and evaluation of a training programme for medical and nursing professionals on best practice for informing families of their child's disability. DESIGN:A 2 h training course on 'Best practice guidelines for informing families of their child's disability' was designed based on the f...

journal_title：Archives of disease in childhood

authors： Harnett A,Bettendorf E,Tierney E,Guerin S,O'Rourke M,Hourihane JO

更新日期：2013-06-01 00:00:00

abstract：:The relationship of vesicoureteric reflex (VUR) and renal scarring was studied in 94 children (188 kidneys) with proved urinary tract infection in a district general hospital. There were 61 girls and 33 boys, with nine girls and 17 boys aged less than 1 year, 31 girls and nine boys aged between 1 and 5 years, the rema...

journal_title：Archives of disease in childhood

authors： Gleeson FV,Gordon I

更新日期：1991-11-01 00:00:00

abstract：AIMS:To investigate whether sagittal synostosis (SS) has consequences for children's mental and psychomotor development, and whether surgery has any impact on this. METHODS:The study involved 28 children with SS who underwent corrective surgery at a mean age of 8.0 (SD 7.16) months, and 28 normal controls. All the chi...

journal_title：Archives of disease in childhood

authors： Bellew M,Chumas P,Mueller R,Liddington M,Russell J

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Paediatric early warning scores (PEWS) are widely used as an adjunct to support staff in recognising deterioration in hospitalised children. Relatively little is known about how staff use these systems. OBJECTIVE:To examine the completeness and accuracy of PEWS recording in hospitalised children in a tertia...

journal_title：Archives of disease in childhood

authors： Chapman SM,Oulton K,Peters MJ,Wray J

更新日期：2019-12-01 00:00:00

abstract：:The fasting serum cholecystokinin-like activity was measured in 21 infants with pyloric stenosis and in 13 normal controls. No significant difference was found between the two groups. The basal acid secretion was measured by continuously aspirating the previously emptied stomach for one hour. The basal gastric volume ...

journal_title：Archives of disease in childhood

authors： Rogers IM,Drainer IK,Dougal AJ,Black J,Logan R

更新日期：1979-10-01 00:00:00

abstract：:In a family in which the father carried a balanced translocation between chromosomes 15 and 22 two of his children had Prader-Willi syndrome and an unbalanced chromosome complement, having lost the proximal bands from the long arm of chromosome 15. His four other surviving children were normal but carried a balanced t...

journal_title：Archives of disease in childhood

authors： Fernandez F,Berry C,Mutton D

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:In recent years photopheresis, an extracorporeal form of photochemotherapy using psoralen and ultraviolet A irradiation of leucocytes, has been claimed to be an effective form of immunomodulation. AIM:To evaluate its effect in type 1 diabetes we performed a double blind, controlled study using placebo table...

journal_title：Archives of disease in childhood

authors： Ludvigsson J,Samuelsson U,Ernerudh J,Johansson C,Stenhammar L,Berlin G

更新日期：2001-08-01 00:00:00

abstract：:Female genital mutilation (FGM) is almost always performed on children and consequently paediatricians should have a central role in the detection and prevention of FGM. FGM has no health benefits and can cause lifelong damage to physical and psychological health. Extensive migration of FGM practising communities mean...

journal_title：Archives of disease in childhood

authors： Creighton SM,Hodes D

更新日期：2016-03-01 00:00:00

abstract：:A 9 year old boy with intractable postprandial reflex vomiting was taught a self hypnotherapy technique incorporating relaxation exercises, mental imagery, and suggestions of symptom relief. The sequence was recorded on a personal stereo cassette tape. Vomiting was completely eliminated within four weeks. At 12 month ...

journal_title：Archives of disease in childhood

authors： Sokel BS,Devane SP,Bentovim A,Milla PJ

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Several studies have shown an increased incidence of neurodevelopmental impairment in very preterm survivors at school age compared with controls. AIM:To compare findings in the same cohort at 8 years and 15 years. METHODS:A total of 151 of the 224 eligible infants born before 33 weeks of gestation from 19...

journal_title：Archives of disease in childhood

authors： O'Brien F,Roth S,Stewart A,Rifkin L,Rushe T,Wyatt J

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:Foot pathology is a major source of morbidity in adults with diabetes. The aim of this study was to determine if children with insulin dependent diabetes have an increased incidence of foot pathology compared with non-diabetic children. DESIGN:Questionnaire, clinical examination, and biomechanical assessmen...

journal_title：Archives of disease in childhood

authors： Barnett SJ,Shield JP,Potter MJ,Baum JD

更新日期：1995-08-01 00:00:00

abstract：:It has been suggested that because of vascular interchange between the monozygous twins vascular disruptions from a deceased cotwin with disseminated intravascular coagulation causes embolisation in the surviving twin. This study reports six cases in which all the surviving monozygous twins had central nervous system ...

journal_title：Archives of disease in childhood

authors： Szymonowicz W,Preston H,Yu VY

更新日期：1986-05-01 00:00:00

abstract：AIM:Several studies have suggested a beneficial effect of infant breastfeeding on childhood cognitive function. The main objective was to examine whether duration of breastfeeding and age at introduction of complementary foods are related to cognitive performance in 9- to 10-year-old school-aged children in South India...

journal_title：Archives of disease in childhood

authors： Veena SR,Krishnaveni GV,Srinivasan K,Wills AK,Hill JC,Kurpad AV,Muthayya S,Karat SC,Nalinakshi M,Fall CH

更新日期：2010-05-01 00:00:00

abstract：:Pyogenic meningitis occurred in 6 infants in the course of chronic gastroenteritis, in 5 of whom a normal CSF had been recorded earlier in the illness. Clinical signs of meningitis were often absent. The problems of diagnosis and management and of possible predisposition to pneumococcal meningitis in children sufferin...

journal_title：Archives of disease in childhood

authors： Wyatt GP,Marcus JC

更新日期：1977-02-01 00:00:00

abstract：AIM:To determine the association between allergic rhinitis, bottle feeding, non-nutritive sucking habits, and malocclusion in the primary dentition. METHODS:Data were collected on 1160 children aged 4-5 years, who had been longitudinally followed since the age of 4 months, when they were admitted to nurseries in a sub...

journal_title：Archives of disease in childhood

authors： Vázquez-Nava F,Quezada-Castillo JA,Oviedo-Treviño S,Saldivar-González AH,Sánchez-Nuncio HR,Beltrán-Guzmán FJ,Vázquez-Rodríguez EM,Vázquez Rodríguez CF

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Congenital facial palsy (CFP) is clinically defined as facial palsy present at birth. It is associated with considerable disfigurement and causes functional and emotional problems for the affected child. The aetiology of the majority of cases however, remains elusive. AIMS:To investigate the role of a neuro...

journal_title：Archives of disease in childhood

authors： Jemec B,Grobbelaar AO,Harrison DH

更新日期：2000-09-01 00:00:00