Pulmonary ventilation and perfusion imaging with dual-energy CT.

Abstract:

OBJECTIVE:To evaluate the feasibility of dual-energy CT (DECT) ventilation imaging in combination with DE perfusion mapping for a comprehensive assessment of ventilation, perfusion, morphology and structure of the pulmonary parenchyma. METHODS:Two dual-energy CT acquisitions for xenon-enhanced ventilation and iodine-enhanced perfusion mapping were performed in patients under artificial respiration. Parenchymal xenon and iodine distribution were mapped and correlated with structural or vascular abnormalities. RESULTS:In all datasets, image quality was sufficient for a comprehensive image reading of the pulmonary CTA images, lung window images and pulmonary functional parameter maps and led to expedient results in each patient. CONCLUSION:With dual-source CT systems, DECT of the lung with iodine or xenon administration is technically feasible and makes it possible to depict the regional iodine or xenon distribution representing the local perfusion and ventilation.

journal_name

Eur Radiol

journal_title

European radiology

authors

Thieme SF,Hoegl S,Nikolaou K,Fisahn J,Irlbeck M,Maxien D,Reiser MF,Becker CR,Johnson TR

doi

10.1007/s00330-010-1866-8

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

2882-9

issue

12

eissn

0938-7994

issn

1432-1084

journal_volume

20

pub_type

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