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Cortex, white matter, and basal ganglia in schizophrenia: a volumetric postmortem study.

Abstract：

:Postmortem volumetry of cortex, white matter, and basal ganglia was performed in 23 brains of schizophrenic patients and 23 brains of controls closely matched for gender, age, and hemisphere. Stereological methods were applied to serial coronal sections of complete hemispheres. We found no significant volume changes of cortex and white matter in schizophrenics. Striatal volume of schizophrenics was increased bilaterally reaching a significant level on the left side. Volumes of the globus pallidus were increased in both hemispheres reaching a significant level on the right side. After psychopathological differentiation, basal ganglia volume increase was also found in the subgroup of paranoid-hallucinatory schizophrenics.

journal_name

Biol Psychiatry

journal_title

Biological psychiatry

authors

Heckers S,Heinsen H,Heinsen Y,Beckmann H

doi

10.1016/0006-3223(91)90091-y

subject

Has Abstract

pub_date

1991-03-15 00:00:00

pages

556-66

issue

6

eissn

0006-3223

issn

1873-2402

pii

0006-3223(91)90091-Y

journal_volume

29

pub_type

杂志文章

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