Intraductal papillary mucinous neoplasms of the pancreas: diagnosis and management.

Abstract:

:Intraductal papillary mucinous neoplasms (IPMNs), characterized by intraductal papillary growth and thick mucin secretion, have increasingly been recognized. Despite modern preoperative evaluation, major difficulties still remain in distinguishing malignant invasive types from benign IPMNs. Following a PubMed database search, all relevant abstracts and articles on IPMN published in English and Chinese were reviewed. Main-duct and the mixed type IPMNs carry a higher risk of malignancy as compared with branch-duct type IPMNs. Treatment of branch-duct type IPMNs remains controversial. Once operation is indicated, intraoperative frozen section of margins plays an important role in the decision concerning the extent and type of surgery. Pancreatectomy, partly preserving both endocrine and exocrine pancreatic function, is advocated for most patients with IPMN, though total pancreatectomy may be necessary in some. Both for patients subjected to surgery and those only observed, IPMN patients need regular close follow-up to identify recurrence or progressive disease.

authors

Dongbin L,Fei L,Werner Josefin B,Roland A

doi

10.1097/MEG.0b013e32833b00f9

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

1029-38

issue

9

eissn

0954-691X

issn

1473-5687

journal_volume

22

pub_type

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