Modification in body weight associated with antiepileptic drugs.

Abstract:

UNLABELLED:Antiepileptic drugs (AED) may cause body weight changes. OBJECTIVE:To evaluate the dietary habits and body weight associated with AED in epileptic patients. METHOD:Sixty-six patients were subjected to two interviews, and had their weight and body mass index calculated and compared at both times, interval between six to eight months. RESULTS:It was observed that 59.1% showed weight gain. The patients who had no weight gain had a greater proportion of individuals who engaged in some form of physical activity. However, of the 45 patients who maintained their initial dietary and medication pattern, 75.6% recorded a weight gain. Weight gain was seen in 66.7% of patients on carbamazepine (n=18), 60% on valproate (n=5), 50% on carbamazepine+clobazam treatment (n=14), and 58.3% of patients on other(s) polytherapy (n=12). CONCLUSION:The patient should be alerted to possible weight gain, and should be advised about dieting and participating in regular physical activity.

journal_name

Arq Neuropsiquiatr

authors

Gaspari CN,Guerreiro CA

doi

10.1590/s0004-282x2010000200024

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

277-81

issue

2

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2010000200024

journal_volume

68

pub_type

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