Abstract:
OBJECTIVE:To study the white matter of patients with multiple sclerosis (MS) with diffusion tensor magnetic resonance (MR) imaging (DTI). METHOD:Forty patients with clinical-laboratorial diagnosis of relapsing-remitting MS and 40 age- and sex-matched controls, who underwent conventional and functional (DTI) MR imaging, were included in the study. The DTI sequences resulted in maps of fractional anisotropy (FA) and regions of interest were placed on the plaques, peri-plaque regions, normal-appearing white matter (NAWM) around the plaques, contralateral normal white matter (CNWM) and normal white matter of the controls (WMC). The FA values were compared and the statistical treatment was performed with the Mann-Whitney U test. RESULTS:The mean FA in plaques was 0.268, in peri-plaque regions 0.365, in NAWM 0.509, in CNWM 0.552 and in WMC 0.573. Statistical significant differences in FA values were observed in plaques, peri-plaque regions and in NAWM around the plaques when compared to the white matter in the control group. There was no significant difference between the FA values of the CNWM of patients with MS and normal white matter of controls. CONCLUSION:Patients with MS show difference in the FA values of the plaques, peri-plaques and NAWM around the plaques when compared to the normal white matter of controls. As a result, DTI may be considered more efficient than conventional MR imaging for the study of patients with MS.
journal_name
Arq Neuropsiquiatrjournal_title
Arquivos de neuro-psiquiatriaauthors
Andrade RE,Gasparetto EL,Cruz LC Jr,Ferreira FB,Domingues RC,Marchiori E,Domingues RCdoi
10.1590/s0004-282x2007000400002subject
Has Abstractpub_date
2007-09-01 00:00:00pages
561-4issue
3Aeissn
0004-282Xissn
1678-4227pii
S0004-282X2007000400002journal_volume
65pub_type
杂志文章abstract:Methods:Review of hospital records and structured telephone interviews of 100 consecutive stroke patients. Forward stepwise logistic regression was used for the statistical analysis. Results:Seventy patients (75%) arrived at the hospital 4.5 hours after stroke symptoms onset. The use of EMS did not improve arrival tim...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/0004-282X20160142
更新日期:2016-11-01 00:00:00
abstract::Through information gathered at the statistical and medical register service it was done a descriptive study of some epidemiologic aspects of neurosyphilis at the Juliano Moreira Hospital (Bahia) in a period of 50 years (1930 - 1979). Coeficients of specific mortality were stablished . The distribution of the disease ...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1984000100004
更新日期:1984-03-01 00:00:00
abstract::This review describes therapeutically relevant mechanisms of action of botulinum toxin (BT). BT's molecular mode of action includes extracellular binding to glycoproteine structures on cholinergic nerve terminals and intracellular blockade of the acetylcholine secretion. BT affects the spinal stretch reflex by blockad...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章,评审
doi:10.1590/s0004-282x2005000100035
更新日期:2005-03-01 00:00:00
abstract:PURPOSE:To assess the outcome of patients with epilepsy treated at primary care health units under the framework of the demonstration project on epilepsy in Brazil, part of the WHO/ILAE/IBE Global Campaign Against Epilepsy. METHOD:We assessed the outcome of patients treated at four primary health units. The staff of t...
journal_title:Arquivos de neuro-psiquiatria
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abstract::More than 80 years after its introduction by Hans Berger, the electroencephalogram (EEG) remains as an important supplementary examination in the investigation of neurological disorders and gives valuable and accurate information about cerebral function. Abnormal EEG findings may include ictal patterns, interictal epi...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章,评审
doi:10.1590/s0004-282x2011000600020
更新日期:2011-10-01 00:00:00
abstract::Stroke mortality rates are higher in Brazil when compared to other countries. The city of São Paulo has a good system of mortality surveillance that allow us to describe the epidemiology of the stroke in the city. Our aim was to describe the stroke mortality pattern by gender and age characterizing the ischemic/ hemor...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2004000600014
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abstract::Subthalamic nucleus deep brain stimulation (STN-DBS) is a surgical technique to treat motor symptoms in patients with Parkinson's disease (PD). Studies have shown that STN-DBS may cause a decline in verbal fluency performance. We aimed to verify the effects of STN-DBS on the performance of phonemic verbal fluency in B...
journal_title:Arquivos de neuro-psiquiatria
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abstract::Cervical carotid stenosis is one of the main causes of ischemic stroke. Carotid endarterectomy is a safe procedure for treatment of moderate and severe symptomatic and asymptomatic carotid stenosis. Regional anesthesia allows neurological evaluation of the patient during the surgery. We reviewed the results of 104 pat...
journal_title:Arquivos de neuro-psiquiatria
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abstract::The objective of this study was to analyze different immunoglobulins classes (IgG, IgM, IgE and IgA) against Cysticercus cellulosae in the cerebrospinal fluid (CSF), through enzyme linked immunosorbent assay (ELISA), correlating them to clinical and tomographic profiles in patients with neurocysticercosis (NCC). Eight...
journal_title:Arquivos de neuro-psiquiatria
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abstract::A protocol for testing cerebrospinal fluid specimens using a range of PCR assays for the diagnosis of central nervous system infection was developed and used to test prospectively 383 specimens. PCR assays were used for the detection of adenovirus, Borrelia burgdorferi, enteroviruses, Epstein Barr virus, cytomegalovir...
journal_title:Arquivos de neuro-psiquiatria
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abstract::A child, who had undergone ventriculoperitoneal shunting, presented with repeated episodes of pneumonia and expectoration of CSF. Chest x-ray demonstrated the presence of the shunt catheter in the base of the left lung. In the present case the distal end of the catheter perforated the diaphragm, entering the thoracic ...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1980000400013
更新日期:1980-12-01 00:00:00
abstract:OBJECTIVE:To describe the clinical activities at the Neuroimmunology Clinic of the Universidade Federal de São Paulo (UNIFESP) from 1994 to 2013. METHOD:The final diagnosis of all patients that attended the center was reviewed and established upon specific guidelines for each disease. The number of total appointments ...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
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journal_title:Arquivos de neuro-psiquiatria
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更新日期:1992-12-01 00:00:00
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journal_title:Arquivos de neuro-psiquiatria
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更新日期:2005-06-01 00:00:00
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1978000200008
更新日期:1978-06-01 00:00:00
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
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abstract::Quantitative electromyography is an important tool to evaluate myopathies, and some difficult-to-treat asthmatic patients may have a subclinical corticosteroid myopathic process, using only inhaled corticosteroid, according to some studies. In this report, diaphragm quantitative electromyography was used to evaluate a...
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2000000600020
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abstract::Intracranial lipoma are usually localized in the corpus callosum and rarely extends to the subgaleal region. Only eight cases of lipoma of the corpus callosum with extracranial extension were reported in the literature. Seizures and mental retardation were the most common clinical findings in these patients. Data from...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:
更新日期:1995-09-01 00:00:00
abstract::Primary progressive multiple sclerosis (PPMS) is defined clinically with a progressive course from onset. There is no approved treatment for the PPMS. Methylprednisolone IV (MP) hastens the recovery from MS relapses. We studied 11 patients that met the MacDonald's diagnostic criteria for PPMS. The dose of MP was 30 mg...
journal_title:Arquivos de neuro-psiquiatria
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journal_title:Arquivos de neuro-psiquiatria
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journal_title:Arquivos de neuro-psiquiatria
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更新日期:1999-03-01 00:00:00
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1993000100020
更新日期:1993-03-01 00:00:00
abstract::There is substantial controversy in literature about human dermatomes. We studied L4, L5, and S1 inferior limb dermatomes by comparing clinical signs and symptoms with conduction studies, electromyographical data, neurosurgical findings, and imaging data from computerized tomography (CT) or magnetic resonance imaging ...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2009000200017
更新日期:2009-06-01 00:00:00
abstract::The neurological involvement in Manson's Schistosomiasis is rarely reported in the literature. The authors describe a case of a 23 years old patient born in São Francisco-MG. She presented with headache, vomiting, fever and stupor. The neurological examination showed stiffness of the neck, paresis with bilateral muscu...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1990000300018
更新日期:1990-09-01 00:00:00
abstract:UNLABELLED:We previously demonstrated correlation between parasympathetic dysfunction and brain white matter lesions in chronic chagasic patients. OBJECTIVE:To correlate serum functional circulating antibodies with beta adrenergic (Ab-beta), muscarinic (Ab-M) or muscarinic and beta adrenergic (Ab-Mbeta) activity, the ...
journal_title:Arquivos de neuro-psiquiatria
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更新日期:2009-09-01 00:00:00
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journal_title:Arquivos de neuro-psiquiatria
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更新日期:2000-06-01 00:00:00
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journal_title:Arquivos de neuro-psiquiatria
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更新日期:2006-06-01 00:00:00
abstract::Pulmonary involvement in HTLV-I patients has been identified by several authors in Africa, Japan and Brazil. The objective of this controlled study is to establish an association between HAM and lymphocytosis in the bronchoalveolar fluid (BAL). Thirty-five adult patients with non-traumatic and non-tumoral myelopathy f...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
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更新日期:1995-12-01 00:00:00
abstract::Obstructive sleep apnea (OSA) occurs in up to 66% of Parkinson's disease (PD) patients, higher than in the general population. Although it is more prevalent, the relationship between OSA and PD remains controversial, with some studies confirming and others denying the relationship of OSA with some risk factors and sym...
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