[Intravenous therapy with methylprednisolone and cyclophosphamide in vasculitis of peripheral nervous system. Evaluation of 8 patients].

Abstract:

:The peripheral nervous system is frequently involved in systemic vasculitis and it may be helpful in the disease diagnosis. We report on eight patients: seven women and one man; five white, two black and one yellow; age mean 55.9 years; four had polyarteritis nodosa, one had systemic lupus erythematosus, one had isolated peripheral nerve vasculitis and one had livedoid vasculitis. All of them received endovenous therapy with "pulse" of methylprednisolone (1 g/day/3 days) and cyclophosphamide (1 g/1 day). Five patients improved, two remained unchanged and one died. The neurological improvement occurred after the third or fourth pulse and in the patients who have had a shorter time of disease.

journal_name

Arq Neuropsiquiatr

authors

Lino AM,Hirata MT,Baêta AM,Tsanaclis AM,Scaff M,Marchiori PE

doi

10.1590/s0004-282x1998000200018

subject

Has Abstract

pub_date

1998-06-01 00:00:00

pages

274-80

issue

2

eissn

0004-282X

issn

1678-4227

journal_volume

56

pub_type

杂志文章
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