Anterior temporal lobectomy versus selective amygdalohippocampectomy in patients with mesial temporal lobe epilepsy.

Abstract:

OBJECTIVE:To contribute our experience with surgical treatment of patients with mesial temporal lobe epilepsy (mTLE) undergoing anterior temporal lobectomy (ATL) or selective amygdalohippocampectomy (SelAH). METHOD:This is a retrospective observational study. The sample included patients with medically refractory mTLE due to unilateral mesial temporal sclerosis who underwent either ATL or SelAH, at Hospital de Clinicas - UFPR, from 2005 to 2012. We report seizure outcomes, using Engel classification, cognitive outcomes, using measurements of verbal and visuospatial memories, as well as operative complications. RESULT:Sixty-seven patients (33 ATL, 34 SelAH) were studied; median follow-up was 64 months. There was no statistically significant difference in seizure or neuropsychological outcomes, although verbal memory was more negatively affected in ATL operations on patients' dominant hemispheres. Higher number of major complications was observed in the ATL group (p = 0.004). CONCLUSION:Seizure and neuropsychological outcomes did not differ. ATL appeared to be associated with higher risk of complications.

journal_name

Arq Neuropsiquiatr

authors

Nascimento FA,Gatto LA,Silvado C,Mäder-Joaquim MJ,Moro MS,Araujo JC

doi

10.1590/0004-282X20150188

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

35-43

issue

1

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2015005011101

journal_volume

74

pub_type

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