Primary headache subtypes and thyroid dysfunction: Is there any association?

Abstract:

BACKGROUND:Primary headaches, and particularly migraine and tension-type headache (TTH) as well as hypothyroidism are common medical conditions. To date, numerous studies have suggested a possible bidirectional relationship between migraine and hypothyroidism, although certain studies had contradictory results. OBJECTIVE:To investigate whether there is any association between primary headache subtypes and thyroid disorders. METHODS:A retrospective study of consecutive patients aged ≥18 years referred to the Headache Outpatient Clinic of Aeginition Hospital and diagnosed with primary headache and any thyroid disorder. RESULTS:Out of 427 patients (males/females=76/351), 253 (59.3%) were diagnosed with migraine without aura, 53 (12.4%) with TTH, 49 (11.5%) with migraine with aura, 29 (6.8%) with medication-overuse headache, 23 (5.4%) with mixed-type headache (migraine with/without aura and TTH), nine (2.1%) with cluster headache, and 11 (2.6%) with other types of primary headaches. The prevalence of any type of thyroid disorder was 20.8% (89/427 patients). In the total sample, 27 patients (6.3%) reported hypothyroidism, 18 (4.2%) unspecified thyroidopathy, 14 (3.3%) thyroid nodules, 12 (2.8%) Hashimoto thyroiditis, 12 (2.8%) thyroidectomy, three (0.7%) thyroid goiter, and three (0.7%) hyperthyroidism. Further statistical analysis between categorical variables did not reveal any significant association between headache subtypes and thyroid dysfunction. CONCLUSIONS:No specific association was found between primary headache subtypes and specific thyroid disorder. However, a high prevalence of thyroid dysfunction in general and specifically hypothyroidism was demonstrated among patients with primary headaches, which lays the foundation for further clarification in prospective longitudinal studies.

journal_name

Arq Neuropsiquiatr

authors

Spanou I,Christidi F,Liakakis G,Rizonaki K,Bougea A,Anagnostou E,Kararizou E

doi

10.1590/0004-282X20200070

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

695-699

issue

11

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2020005028101

journal_volume

78

pub_type

杂志文章
  • Evaluation of upper endoscopic findings in patients with restless legs syndrome and gastric complaints.

    abstract:BACKGROUND:The effect of gastrointestinal system disorders on Restless Legs Syndrome/Willis-Ekbom disease (RLS/WED) has been previously demonstrated by using serological tests. However, this association has not been supported by histopathological studies so far. OBJECTIVE:To investigate the relationship between RLS/WE...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/0004-282X20190192

    authors: Çam M,Kutluana U

    更新日期:2020-04-01 00:00:00

  • Management of rheumatic chorea: an observational study.

    abstract:BACKGROUND:Rheumatic chorea (RC) has recently been linked to an antibody-mediated immune mechanism. OBJECTIVE/METHOD:To verify if this knowledge reflected in management changes we conceived a descriptive study. RESULTS:The medical charts of 20 children (13 females) aged 6 to 12 years (mean 8 years), diagnosed as RC f...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:

    authors: Araujo AP,Padua PA,Maia Filho HS

    更新日期:2002-06-01 00:00:00

  • [Status epilepticus in Lennox-Gastaut syndrome; therapeutic aspects].

    abstract::Therapeutic aspects of convulsive and non convulsive status epilepticus observed in fourteen patients with Lennox-Gastaut syndrome were studied. A temporal relationship between the status epilepticus onset and the beginning of treatment with chlonazepam and diphenylhydantoin was observed; these drugs withdrawal was fo...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1977000300006

    authors: Speciali JG,Lison MP

    更新日期:1977-09-01 00:00:00

  • [Myelination, demyelination and re-myelination in the central nervous system].

    abstract::The myelin sheaths that surround axons in the CNS are made and maintained by oligodendrocytes. These glial cells can form variable numbers of myelin segments (internodules): from 1 to 200 so that when one oligodendrocyte is destroyed with preservation of the axon, many internodules can be lost, constituting a demyelin...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章,评审

    doi:10.1590/s0004-282x1988000300010

    authors: Graça DL

    更新日期:1988-09-01 00:00:00

  • Quantification of cerebrospinal fluid ferritin as a biomarker for CNS malignant infiltration.

    abstract::Several markers have been studied for their ability to make the CNS infiltration diagnosis earlier and more precise; previous studies showed that CSF ferritin concentrations were higher in patients with malignant invasion of CNS. The objective was to determine the importance of CSF ferritin as a biomarker for the diag...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2008000500022

    authors: Almeida SM,Cunha DS,Yamada E,Doi EM,Ono M

    更新日期:2008-09-01 00:00:00

  • Diagnosis of, surgical technique for and treatment results from medullary lipomas associated with spinal dysraphism: experience with 38 patients.

    abstract:OBJECTIVE:To observe whether microsurgical removal of medullary lipomas and untethering of the medulla is a safe and efficient procedure. METHOD:A retrospective study was carried out on 38 patients with medullary lipomas associated with spinal dysraphism who underwent operations between January 1986 and January 2008, ...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2011000500019

    authors: Lynch JC,Corrêa J,Pereira C

    更新日期:2011-08-01 00:00:00

  • Intraventricular pressure monitoring in patients with thalamic and ganglionic hemorrhages.

    abstract::In the present study, we have evaluated the use of intraventricular pressure catheters in thalamic and ganglionic hemorrhages. Ten patients admitted in our Emergency Department in Glasgow Coma Scale (GCS) equal or below 13 enrolled the study (at least one point should have been lost in the eye opening score to exclude...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2003000300010

    authors: Hamani C,Zanetti MV,Pinto FC,Andrade AF,Ciquini O Jr,Marino R Jr

    更新日期:2003-06-01 00:00:00

  • Post-poliomyelitis syndrome: case report.

    abstract::The post-polio syndrome (PPS) is an entity characterized for an episode of muscular weakness and/or abnormal muscular fatigue in individuals that had presented acute polio years before. We report the case of PPS in a patient, 40 years, that thirty-five years after had had paralytic poliomyelitis, developed new symptom...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2007000300033

    authors: Neves MA,Mello MP,Santos VV,Nascimento OJ,Antonioli Rde S,Freitas GR,Freitas MR

    更新日期:2007-06-01 00:00:00

  • Neurodegenerative changes in the brainstem and olfactory bulb in people older than 50 years old: a descriptive study.

    abstract::With the increase in life expectancy in Brazil, concerns have grown about the most prevalent diseases in elderly people. Among these diseases are neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases. Protein deposits related to the development of these diseases can pre-date the symptomatic phases b...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/0004-282X20150066

    authors: Oliveira FH,Rodrigues Neto E,Fonseca MK,Costa AS,Rockenbach MA,Padilha Rdos S,Fernandez LL,Hilbig A

    更新日期:2015-07-01 00:00:00

  • Quetiapine for the prevention of migraine refractory to the combination of atenolol + nortriptyline + flunarizine: an open pilot study.

    abstract:BACKGROUND:Migraine is a prevalent neurological disorder. Although prevention is the mainstream treatment, some patients are refractory to standard therapies. AIM:To evaluate the use of quetiapine (QTP) in the preventive treatment of refractory migraine, defined as previous unresponsiveness to the combination atenolol...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2008000500002

    authors: Krymchantowski AV,Jevoux C

    更新日期:2008-09-01 00:00:00

  • Sleep disorders in cerebellar ataxias.

    abstract::Cerebellar ataxias comprise a wide range of etiologies leading to central nervous system-related motor and non-motor symptoms. Recently, a large body of evidence has demonstrated a high frequency of non-motor manifestations in cerebellar ataxias, specially in autosomal dominant spinocerebellar ataxias (SCA). Among the...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章,评审

    doi:10.1590/s0004-282x2011000200021

    authors: Pedroso JL,Braga-Neto P,Felício AC,Aquino CC,Prado LB,Prado GF,Barsottini OG

    更新日期:2011-04-01 00:00:00

  • Clinical, laboratory and neuroimage findings in juvenile systemic lupus erythematosus presenting involvement of the nervous system.

    abstract:OBJECTIVE:To characterize neurological involvement in juvenile systemic lupus erythe-matosus. METHOD:The charts of all patients with the diagnosis of systemic lupus erythematosus before the age of 16 years, followed at the Rheumatology Unit of Pequeno Príncipe Hospital, from January 1992 to January 2006, were retrospe...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2007000300013

    authors: Spinosa MJ,Bandeira M,Liberalesso PB,Vieira SC,Janz LL Jr,Sá EG,Löhr A Jr

    更新日期:2007-06-01 00:00:00

  • Frontal assessment battery in a Brazilian sample of healthy controls: normative data.

    abstract:OBJECTIVE:To show data on the performance of healthy subjects in the Frontal Assessment Battery (FAB), correlating with gender, age, education, and scores in the Mini-Mental State Examination (MMSE). METHODS:Two hundred and seventy-five healthy individuals with mean age of 66.4 ± 10.6 years-old were evaluated. Mean to...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2012005000009

    authors: Beato R,Amaral-Carvalho V,Guimarães HC,Tumas V,Souza CP,Oliveira GN,Caramelli P

    更新日期:2012-04-01 00:00:00

  • [Neurosyphilis mortality in a psychiatric hospital over a 50-year period].

    abstract::Through information gathered at the statistical and medical register service it was done a descriptive study of some epidemiologic aspects of neurosyphilis at the Juliano Moreira Hospital (Bahia) in a period of 50 years (1930 - 1979). Coeficients of specific mortality were stablished . The distribution of the disease ...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1984000100004

    authors: Costa GF

    更新日期:1984-03-01 00:00:00

  • Giant intrathoracic meningoceles associated with cutaneous neurofibromatosis type I: case report.

    abstract:BACKGROUND:Intrathoracic meningocele is a rare pathology, almost always associated with neurofibromatosis type I and with a few cases related in the literature. In the majority of cases cysts are small or asymptomatic, and the surgery is indicated when big or symptomatic cysts are present. We report a case of giant int...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章,评审

    doi:10.1590/s0004-282x2003000400029

    authors: de Andrade GC,Braga OP,Hisatugo MK,de Paiva Neto MA,Succi E,Braga FM

    更新日期:2003-09-01 00:00:00

  • High phenotypic variability in Gerstmann-Sträussler-Scheinker disease.

    abstract::Gerstmann-Sträussler-Scheinker is a genetic prion disease and the most common mutation is p.Pro102Leu. We report clinical, molecular and neuropathological data of seven individuals, belonging to two unrelated Brazilian kindreds, carrying the p.Pro102Leu. Marked differences among patients were observed regarding age at...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/0004-282X20170049

    authors: Smid J,Studart A Neto,Landemberger MC,Machado CF,Nóbrega PR,Canedo NHS,Schultz RR,Naslavsky MS,Rosemberg S,Kok F,Chimelli L,Martins VR,Nitrini R

    更新日期:2017-06-01 00:00:00

  • Autism spectrum disorder and celiac disease: no evidence for a link.

    abstract:OBJECTIVE:To evaluate the possible association between celiac disease (CD) and/or gluten sensitivity (GS) and autism spectrum disorder (ASD). METHODS:Occurrences of CD were determined in a group of children and adolescents affected by ASD and, conversely, occurrences of ASD were assessed in a group of biopsy-proven ce...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2012000100007

    authors: Batista IC,Gandolfi L,Nobrega YK,Almeida RC,Almeida LM,Campos Junior D,Pratesi R

    更新日期:2012-01-01 00:00:00

  • [Brothers affected by the Charcot-Marie-Tooth peroneal muscular atrophy with a positive variant of the anticipation phenomenon].

    abstract::Considering the genetical peculiarity of Charcot-Marie-Tooth's muscular atrophy, a family with three affected brothers was investigated, in which beginning date was discovered to be progressively antedated. Afterwards, this possible variant of anticipation is discussed, because such condition is quite ununsual, not on...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1977000200011

    authors: Gonçalves A,da Salva JB

    更新日期:1977-06-01 00:00:00

  • [Neurocysticercosis in a State of Piauí urban area: case report].

    abstract::Neurocysticercosis is a serious public health problem that predominantly affects places with poor sanitary and hygiene conditions. The Piaui State is out of the neurocysticercosis map in Brazil but, as this study illustrates, it is just by lack of epidemiologic data. We demonstrate the presence of this pathology in th...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2006000200030

    authors: e Silva do Rego Monteiro AV,da Silva Júnior AN,Leite DA,Mendes LC,de Assunção Cordeiro M,Lima RF,Lima FC,Batista MS

    更新日期:2006-06-01 00:00:00

  • Neuromuscular transmission studies in human chronic Chagas' disease.

    abstract::An electrophysiological investigation of the state of the neuromuscular transmission (nmt) was carried out in 58 patients with the diagnosis of chronic Chagas' disease. On repetitive supramaximal nerve stimulation it was found that some patients did not show abnormalities, others had decremental muscle responses, othe...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1989000300004

    authors: Erro MG,Genovese O,Correale J,Sica RE

    更新日期:1989-09-01 00:00:00

  • [Migraine headache and syndrome of mitral valve prolapse. Report of 50 cases].

    abstract::Fifty patients with prolapse of the mitral valve and clinical diagnosis of migraine are analyzed, all being given a cardio-circulatory examination for an adequate clinical correlation between both illnesses. In this study we show a comparison of the patient's age, the duration and frequency of cephalic attacks, and th...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1994000300012

    authors: Cavalcanti CE,de Castro Júnior AN

    更新日期:1994-09-01 00:00:00

  • Neuroimaging in Parkinsonism: a study with magnetic resonance and spectroscopy as tools in the differential diagnosis.

    abstract::The differential diagnosis of Parkinsonism based on clinical features, sometimes may be difficult. Diagnostic tests in these cases might be useful, especially magnetic resonance imaging, a noninvasive exam, not as expensive as positron emission tomography, and provides a good basis for anatomical analysis. The magneti...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2009000100002

    authors: Vasconcellos LF,Novis SA,Moreira DM,Rosso AL,Leite AC

    更新日期:2009-03-01 00:00:00

  • [Neurobrucellosis: report of 3 cases].

    abstract::Three cases of probable neurobrucellosis are reported. The diagnosis was made on the basis of immunological tests. Two patients with a clinical picture of meningomyelitis showed a definitive clinical improvement under tetracycline and streptomycin therapy. The immunological reactions found in the record case were even...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1981000200009

    authors: Guerreiro CA,Scaff M,Callegaro D,Facure NO,Dianin VM

    更新日期:1981-06-01 00:00:00

  • Postural instability and falls are more frequent in Parkinson's disease patients with worse trunk mobility.

    abstract:OBJECTIVE:Correlate the occurrence of falls and the activity of rolling over in bed with performance on the Trunk Mobility Scale (TMS) in patients with PD, and determine whether this instrument score can predict the risk of falls. METHOD:This is a cross-sectional study. Assessed patients reported the frequency of fall...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/0004-282X20160074

    authors: Artigas NR,Franco C,Leão P,Rieder CR

    更新日期:2016-07-01 00:00:00

  • [Normal pattern of intraepidermal nerve fibers in 30 healthy volunteers with PGP 9.5].

    abstract::Skin biopsy has become an attractive technique to evaluate the terminal regions of small nerve fibers. There is extensive innervation of the skin by both sensory and autonomic fibers as demonstrated by staining for the pan-axonal marker PGP 9,5. The normal pattern is fundamental before any study, since three different...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2004000200015

    authors: Moura L,Oliveira AS,Zanoteli E,Cardoso R,Schmidt B,Gabbai AA

    更新日期:2004-06-01 00:00:00

  • Perception of stroke symptoms and utilization of emergency medical services.

    abstract:Methods:Review of hospital records and structured telephone interviews of 100 consecutive stroke patients. Forward stepwise logistic regression was used for the statistical analysis. Results:Seventy patients (75%) arrived at the hospital 4.5 hours after stroke symptoms onset. The use of EMS did not improve arrival tim...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/0004-282X20160142

    authors: Hawkes MA,Farez MF,Calandri IL,Ameriso SF

    更新日期:2016-11-01 00:00:00

  • Hypersomnia in Whipple disease: case report.

    abstract::Whipple disease (WD) is a rare systemic infection caused by Tropheryma whippelii. Neurological involvement has been recognised in 40% of patients, either as initial manifestations or during the course of the disease. We report on a 45 years-old man with WD with initial, persistent and irresistible episodes of daytime ...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x2006000500030

    authors: Maia LF,Marta M,Lopes V,Rocha N,Lopes C,Martins-da-Silva A,Monteiro L

    更新日期:2006-09-01 00:00:00

  • [Neurofibromatosis and extensive intracranial arterial occlusive disease (moyamoya disease). Report of a case].

    abstract::A 33-year-old female with neurofibromatosis and intracranial vascular lesions of the Moya-Moya type is reported. Clinical and angiographic aspects of both syndromes are discussed with respect to earlier reports of this rare association, with the conclusion that it produces slow intellectual and motor deterioration in ...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1986000400011

    authors: Gracia CM,Bittencourt PC,Mazer S,Bittencourt PR

    更新日期:1986-12-01 00:00:00

  • [Comparison of the neuropsychological assessment in a girl with bilateral cerebrovascular disease (moyamoya) before and after surgical intervention].

    abstract::Moyamoya is a chronic progressive cerebrovascular disease with characteristic angiographic findings and a clinical picture with episodes of transient ischemic attacks, headache, seizures, hemiparesis, which may resolve after surgical treatment. We describe the case of a girl with the typical findings of the disease, c...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章

    doi:10.1590/s0004-282x1999000600024

    authors: Ciasca SM,Alves HL,Guimarães IE,Terra AP,Moura-Ribeiro MV,Camargo EE,Etchebehere ES,Santos Ade O

    更新日期:1999-12-01 00:00:00

  • Neurocysticercosis.

    abstract::Cysticercosis is one of the most common parasitic diseases of the nervous system in humans, and constitutes a major public health problem for most of the developing world. The clinical manifestations of neurocysticercosis (NCC) largely depend on the the host immune response against the parasite. NCC diagnosis is based...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章,评审

    doi:10.1590/0004-282X20130156

    authors: Takayanagui OM

    更新日期:2013-09-01 00:00:00