Experimental nodel of C6 brain tumors in athymic rats.

Abstract:

:Malignant brain tumor experimental models tend to employ cells that are immunologically compatible with the receptor animal. In this study, we have proposed an experimental model of encephalic tumor development by injecting C6 cells into athymic Rowett rats, aiming at reaching a model which more closely resembles to the human glioma tumor. In our model, we observed micro-infiltration of tumor cell clusters in the vicinity of the main tumor mass, and of more distal isolated tumor cells immersed in normal encephalic parenchyma. This degree of infiltration is superior to that usually observed in other C6 models.

journal_name

Arq Neuropsiquiatr

authors

Miura FK,Alves MJ,Rocha MC,Silva RS,Oba-Shinjo SM,Uno M,Colin C,Sogayar MC,Marie SK

doi

10.1590/s0004-282x2008000200019

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

238-41

issue

2A

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2008000200019

journal_volume

66

pub_type

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