Cognitive function assessment in idiopathic Parkinson's disease.

Abstract:

:Idiopathic Parkinson's disease (PD) is characterized by reduced nigrostriatal and cortical dopaminergic influence, with changes in movement and, subsequently, behavioral and cognitive disturbances. We studied cognitive impairment in Parkinson's disease by assessing a group of 30 idiopathic Parkinson's disease patients with an average age of 64.23 years (PG group) and compared our findings with those for a control group of 30 patients (CG group). All the patients were submitted to the following assessments: motor function, using the UPDRS; staging, using the Hoehn-Yahr scales (PG group only); depression, using the Montgomery-Asberg scale; attention impairment; verbal fluency (FAR and animals); cognitive function, using the Mini Mental State Examination; visuospatial and executive functions; and clock drawing. In addition to altered motor function in PD patients, we found statistically significant differences between PD patients and controls in terms of cognitive function, verbal, executive and visuospatial functions, and attention deficits. Depression was more prevalent in the PG group.

journal_name

Arq Neuropsiquiatr

authors

Piovezan MR,Teive HA,Piovesan EJ,Mader MJ,Werneck LC

doi

10.1590/s0004-282x2007000600003

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

942-6

issue

4A

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2007000600003

journal_volume

65

pub_type

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