Stereotactic biopsy for intracranial lesions: clinical-pathological compatibility in 60 patients.

Abstract:

OBJECTIVE:Image guided stereotactic biopsy (SB) provides cerebral tissue samples for histological analysis from minimal lesions or those that are located in deep regions, being crucial in the elaboration of therapeutic strategies, as well as the prevention of unnecessary neurosurgical interventions. METHOD:Sixty patients with central nervous lesions underwent SB from November 1999 to March 2008. They were followed up to 65 months. Preoperative diagnosis was based on clinical presentation and neuro-radiological features, pathologic diagnosis, clinical outcome. The compatibility of these findings with the pathologic diagnosis was analyzed. RESULTS:Considering diagnosis confirmation when inflammatory hypothesis were made, our accuracy was of 76%, with 94% of those cases having clinic-pathological correspondence after an average of 65.2 months of follow up. Considering diagnosis confirmation with the preoperative hypothesis of neoplasm, our accuracy was of 69% with 90% of these cases having clinic-pathological correspondence after an average of 47.3 months of follow-up. Morbidity rate was of 5% and mortality was zero. The diagnosis rate was 95%. CONCLUSION:Stereotactic biopsy represents a safe and precise method for diagnosis. Anatomic and histopathological analyses have high compatibility with long-term clinical outcome.

journal_name

Arq Neuropsiquiatr

authors

Silva EU,Vasconcellos LP,Lara NA Jr,Veiga JC,Lancellotti CL,Shiozawa P

doi

10.1590/s0004-282x2009000600019

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

1062-5

issue

4

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2009000600019

journal_volume

67

pub_type

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