Abstract:
:Ketogenic diet (KD) is a high fat and low carbohydrate diet, which controls refractory epilepsy. We analyzed the KD effects on 54 children of the Children's Institute of the University of São Paulo. Efficacy, tolerability, and adverse effects were studied. Response to KD was effective (E) if seizure control was >75%, good (G) when 50-75%. When possible, we correlated the results with the epileptic syndrome and patient's age. By the second month on diet, 57.4% of the patients had E response and 31.4% G results. At the 6th month, 63.8% had E response and 25.5% G. At the 12th month, 71.8% had E and 25.6% G. At the 24th month, 62.1% had E and 37.9% G. Antiepileptic drugs have been reduced, and generalized epilepsy was the most sensitive. Age-related differences were not observed. Adverse effects were rarely observed. In conclusion, KD proved to be an effective treatment for refractory epilepsy.
journal_name
Arq Neuropsiquiatrjournal_title
Arquivos de neuro-psiquiatriaauthors
Freitas A,Paz JA,Casella EB,Marques-Dias MJdoi
10.1590/s0004-282x2007000300003subject
Has Abstractpub_date
2007-06-01 00:00:00pages
381-4issue
2Beissn
0004-282Xissn
1678-4227pii
S0004-282X2007000300003journal_volume
65pub_type
杂志文章abstract::The existence of a benign multiple sclerosis (BMS) form is a controversial subject. Recent studies of these patients reveal different levels of cognitive impairment, despite the apparent preservation of motor function. The objective of this study was to review and analyze a number of publications that discuss the gene...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章,评审
doi:10.1590/0004-282X20170043
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To study the brain areas which are activated when normal subjects make moral judgments. METHOD:Ten normal adults underwent BOLD functional magnetic resonance imaging (fMRI) during the auditory presentation of sentences that they were instructed to silently judge as either "right" or "wrong". Half of the sent...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2001000500001
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abstract::Epilepsy is one of the most dreaded and terrifying human afflictions. One of the many names it has received was Sacred Disease, during Greek times. Heracles served as a source of the divine connotation that epilepsy received in ancient times, as he was one of the most important demigods in Greek mythology. However, se...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 历史文章,杂志文章,评审
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章,评审
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abstract::Genetic and environmental factors affect the pathogenesis of Parkinson's disease (PD). Genetic variants of the enzyme glutathione S-transferases (GST) may be related to the disease. This study aimed to evaluate the influence of genetic variants of GST (GSTT1/GSTM1) and their association with the exposure to environmen...
journal_title:Arquivos de neuro-psiquiatria
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doi:10.1590/0004-282X20130076
更新日期:2013-08-01 00:00:00
abstract::The relationship between depression and epilepsy has been known since ancient times, however, to date, it is not fully understood. The prevalence of psychiatric disorders in persons with epilepsy is high compared to general population. It is assumed that the rate of depression ranges from 20 to 55% in patients with re...
journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章,评审
doi:10.1590/s0004-282x2013000300011
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abstract::The case of a 24 years-old woman with weakness since the teens and progressive loss of muscle strength is reported. The muscle biopsy showed increased number of mitochondria. In two occasions the respiratory chain enzymes showed important reduction of the succinate-cytochrome-C-reductase, suggesting a possible defect ...
journal_title:Arquivos de neuro-psiquiatria
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doi:10.1590/s0004-282x1989000400013
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 传,历史文章,杂志文章
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journal_title:Arquivos de neuro-psiquiatria
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1978000100010
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journal_title:Arquivos de neuro-psiquiatria
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doi:10.1590/s0004-282x1999000500026
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journal_title:Arquivos de neuro-psiquiatria
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1994000100024
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x1980000300011
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
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journal_title:Arquivos de neuro-psiquiatria
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2004000500009
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journal_title:Arquivos de neuro-psiquiatria
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
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更新日期:1986-12-01 00:00:00
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journal_title:Arquivos de neuro-psiquiatria
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journal_title:Arquivos de neuro-psiquiatria
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
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journal_title:Arquivos de neuro-psiquiatria
pub_type: 杂志文章
doi:10.1590/s0004-282x2009000600009
更新日期:2009-12-01 00:00:00
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