Abstract:
:A 3-month-old boy with hypotonia at birth succumbed to a congenital myopathy. The major finding in his muscle biopsy corresponded to I-Z-I complexes described previously in embryonic skeletal muscle. A few previous myopathy cases have described findings suggestive of I-Z-I-like complexes. A mutation affecting mononuclear myoblasts or early myotubes was suspected, although an acquired lesion could not be ruled out. The findings may also have been altered by secondary events in this unusual case.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Rhodes RH,Sharer LRdoi
10.1002/mus.21575subject
Has Abstractpub_date
2010-05-01 00:00:00pages
715-23issue
5eissn
0148-639Xissn
1097-4598journal_volume
41pub_type
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