Abstract：
INTRODUCTION:Throughout history a number of speculations have been put forward concerning the functional role of the pineal gland, perhaps some of the most important being the neurophysiological proposals by Descartes. DEVELOPMENT:The psychophysiological role conferred on the pineal gland by Descartes in the 17th century, that is, as the seat of the human soul, had barely any scientific support at the time. Throughout the 18th century interest in the pineal gland gradually declined and it was considered to be just a vestigial evolutionary element until the second half of the 19th century, thanks to the boom of comparative anatomy, which confirmed the photoreceptive role of the parietal organ of the anurans, and of microscopic anatomy, which revealed the histological structure of the pineal gland of mammals. CONCLUSIONS:In the early 20th century the first data were published in the scientific literature on the endocrine aspect of the pineal gland (on the relation between pineal tumours and precocious puberty), but its ultimate confirmation took place in 1958, with the isolation of melatonin by the team led by Aaron B. Lerner. Later, the term 'neuroendocrine transducer' was introduced to explain the principle of the pineal gland, that is to say, the transformation of information about light from the retina into an endocrine response consisting in the synthesis and release of the hormone melatonin. In turn, this hormone acts as a powerful neurotransmitter in the central nervous system, which makes the pineal gland a kind of 'biological clock'.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
López-Muñoz F,Marín F,Alamo Csubject
Has Abstractpub_date
2010-01-16 00:00:00pages
117-25issue
2eissn
0210-0010issn
1576-6578pii
rn2009215journal_volume
50pub_type
历史文章,杂志文章,评审abstract：TITLE:Encefalopatia necrotizante aguda. : ...
journal_title：Revista de neurologia
pub_type： 信件
doi：10.33588/rn.6908.2019113
更新日期：2019-10-16 00:00:00
abstract：INTRODUCTION:Vascular lesions produced as a consequence of surgical spinal treatment are rare, but serious. Fast diagnosis and treatment are essential in lesions that produce massive blood loss. Following the use of non covered stents in the treatment of peripheral vascular stenotic obstructive pathologies, the appeara...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-06-16 00:00:00
abstract：:In embryonic mesencephalic transplant in patients with Parkinson s disease dopaminergic survival is low (5 10%), and for this reason the use of multiple donors has been considered. The difficulty of obtaining more tissue determines the need for a procedure that enables human nigral tissue to be stored for a time witho...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
abstract：INTRODUCTION:The ganglioside GM1 has been shown to be effective in the treatment of experimental cerebral ischemia. Gangliosides from bovine brain have not been used in the treatment of ischemic cerebral accidents. There is evidence suggesting that they may also be effective. RESULTS:Ten minutes of bilateral occlusion...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：INTRODUCTION:Recent studies suggest that furosemide (FUR), a chloride cotransporting antagonist, acts directly on neurons of central nervous system modifying the ionic flow. OBJECTIVE:The aim of the present study was to determine the extrarenal antiedema effect of FUR. MATERIAL AND METHODS:Male Sprague-Dawley rats we...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-03-01 00:00:00
abstract：INTRODUCTION:The search for variables that mediate in the shift from mild cognitive impairment (MCI) to dementia is currently a very active field of research. In this area, the term cognitive plasticity or modifiability can be of great interest. Proof of the existence of plasticity in the elderly with MCI and its possi...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-04-01 00:00:00
abstract：INTRODUCTION:The current advances in the field of human genetics allow for the development of alternative therapies for the treatment of diseases affecting the central nervous system (CNS). One of the most promising new therapies is the use of therapeutic genes or gene therapy. OBJECTIVE:To briefly review the recent a...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-07-16 00:00:00
abstract：INTRODUCTION:Epileptic seizures and epilepsy are part of daily clinical practice in neurology. Yet, the number of false positive diagnoses is surprisingly high. Almost one out of every five patients treated for epilepsy does not really have this diagnosis, which is a high percentage bearing in mind the social and medic...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：10.33588/rn.6806.2018242
更新日期：2019-03-16 00:00:00
abstract：INTRODUCTION:Language widely varies in children with autism spectrum disorders (ASD). Evidence, however, suggests that these children understand language worse than their peers with typical development, showing a delay in acquisition of receptive vocabulary. Research relating quality of life (QOL) and language is limit...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:The spinocerebellar ataxia type 2 has a prevalence of 43 per 100,000 inhabitants in Holguín province, which is the highest one reported worldwide. It is due to an intergenerational CAG repeat expansion contained in the first exon of disease causing gene, and it is characterized by a high variability in its...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-12-16 00:00:00
abstract：INTRODUCTION AND MATERIAL:Nine brains belonging to early onset Alzheimer disease (E280A-PS1 mutation) affected individuals from Antioquia, Colombia, were analyzed by neuropathological standard techniques. All individuals were ascertained from genealogies descendents from a common ancestor that shows a dominant autosomi...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-07-01 00:00:00
abstract：AIM:To describe the characteristics of a telephone attendance system (TAS) implemented in our dementia unit, its relevance in the global activity and the users-themselves utility and satisfaction. MATERIALS AND METHODS:We retrospectively analyzed the incoming telephone calls during a period of one year. Telephone call...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2009-03-01 00:00:00
abstract：OBJECTIVES:To evaluate the diagnostic efficacy of an intra-arterial electroencephalographic recording and determine which patients obtain most benefit from this technique, to compare the results obtained using other recording techniques and to establish a standard for recording. PATIENTS AND METHODS:We made 64 intra-a...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-04-01 00:00:00
abstract：INTRODUCTION:Posconcussional syndrome is characterized by a heterogeneous group of somatic, cognitive and psychosocial symptoms, which occur in patients with head trauma, generally of mild severity. It is the neuropsychiatric postraumatic disorder more prevalent in the field of forensic medicine. DEVELOPMENT:Classical...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2001-05-01 00:00:00
abstract：OBJECTIVE:Previous epidemiologic studies have shown that around 5% of the population will suffer a tonic clonic seizure during their life. The aim of this study is to know how many and which of these people will suffer a second seizure and become epileptic. PATIENTS AND METHODS:175 patients seen in the emergency depar...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-05-16 00:00:00
abstract：INTRODUCTION:Essential thrombocythemia (ET) is a myelodysplastic syndrome that constitutes an infrequent cause of ischemic stroke. Few clinical reports have been published describing the clinical onset of ET in the form of a vascular accident. CASE REPORT:We describe four cases of patients with no known haematological...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：INTRODUCTION:Multiple sclerosis is a demyelinating neurological disease that usually gives rise to motor, perceptive, affective and cognitive disorders in patients. These symptoms can lead the person to lose his or her job and lower the quality of life of both patients and their relatives. AIM:To review the literature...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2014-02-16 00:00:00
abstract：INTRODUCTION:An arterial gas embolism is defined as the presence of air in the arterial circulation. This is an extremely rare cause of stroke that has been described in a multitude of clinical scenarios, generally related to iatrogenic processes. A clinical case is reported in which the arterial gas embolism occurred ...
journal_title：Revista de neurologia
pub_type：
doi：10.33588/rn.6903.2019178
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:In this paper we review the main aetiologies of metabolic origin which cause epilepsy in children aged between 1 and 10 years. DEVELOPMENT:There are many aetiological causes of convulsive seizures. Seizures and epilepsies due to congenital errors of metabolism are a minority but should be known. Their identi...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-09-01 00:00:00
abstract：AIMS:We review one of the most important functional techniques in magnetic resonance imaging, perfusion MRI (pMRI) with emphasis in its applications, particularly in the diagnosis and follow up of brain lesions. First, we discuss the physical principles and results of the technique, then, we discuss its major applicati...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2010-01-01 00:00:00
abstract：:Visuospatial impairment has been frequently reported in Parkinson's disease (PD). We present the progressive distortion performance of the Rey-Osterrieth complex figure in parkinsonian patients at different stages of the disease (PD de novo, PD on long-term treatment, PD with phychosis and PD with dementia). ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-02-16 00:00:00
abstract：INTRODUCTION:Glutaric aciduria type I is an autosomal recessive inborn error of metabolism that is due to a deficiency of the enzyme glutaryl-CoA dehydrogenase, which gives rise to an accumulation of glutaric and 3-hydroxyglutaric acids in biological fluids. Clinical features present as a sudden-onset severe neurologic...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-05-16 00:00:00
abstract：INTRODUCTION:Generalised dystonia is an entity that does not usually respond well to medical treatment. Different surgical targets have therefore been used in the treatment of dystonia, including several thalamic nuclei or the internal globus pallidus. The subthalamic nucleus plays a fundamental role in the physiology ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-09-16 00:00:00
abstract：INTRODUCTION:Only the organic and cryptogenic forms of frontal lobe epilepsy have been admitted by the ILAE, but according to several reports in the literature, it probably exists also an idiopathic form, at present not well recognized. OBJECTIVE:To study the differences between the organic and the cryptogenic forms o...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1998-06-01 00:00:00
abstract：INTRODUCTION:The early years of life, more especially the first three, are dominated by a series of anatomical-functional facts that express the progressive enrichment of behaviour through the process of neurological maturation, which is expressed as reaching the maximum level of functioning at each stage of developmen...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-06 00:00:00
abstract：INTRODUCTION:From time to time the debate over whether early-onset epileptic seizures are harmless or have harmful effects on the developing brain reappears. DEVELOPMENT:We evaluated the results of clinical studies reporting the long-term cognitive development of children who suffer from early-onset epilepsies, that i...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2007-05-21 00:00:00
abstract：:Different therapeutic models have been presented with which to treat the condition of attention deficit hyperactivity disorder (ADHD) and the scientific literature speaks of the benefits linked to multimodal approaches. The National Institute of Mental Health report grants combined treatments an essential role. Throug...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-02-01 00:00:00
abstract：INTRODUCTION:Restless legs syndrome (RLS) is a usual neurologic disorder, often undiagnosed and treatable, usually associated with sleep disturbance. Our goal was to study prevalence of RLS in our practice. PATIENTS AND METHODS:Descriptive, cross-sectional study, in a Primary care center. 283 patients 50 years old or ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-06-01 00:00:00
abstract：INTRODUCTION:The advantages of care in stroke units (UI) are known, as are those of being in neurology wards as compared with the general medical wards, although to date there are no studies which make a comparative evaluation of the stroke team (EI) as compared with the UI with regard to benefits in care obtained by t...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-01-16 00:00:00
abstract：:Treatment of stroke is effective when given straight away at the onset of symptoms. Our objective was to find what the present latent periods in the medical attention of stroke patients are. A study was made in 18 hospital neurology units. The time elapsed between onset of the stroke and being attended by a doctor in ...
journal_title：Revista de neurologia
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1996-04-01 00:00:00
