Abstract：
INTRODUCTION:From time to time the debate over whether early-onset epileptic seizures are harmless or have harmful effects on the developing brain reappears. DEVELOPMENT:We evaluated the results of clinical studies reporting the long-term cognitive development of children who suffer from early-onset epilepsies, that is to say, in children with brain immaturity: neonatal epilepsies, West's syndrome, Dravet's syndrome, benign myoclonic epilepsy in infancy, myoclonic-astatic epilepsy and Lennox-Gastaut syndrome; we also report on the harmful influence of certain antiepileptic drugs, such as phenobarbital and valproate, on the immature brain. CONCLUSIONS:The negative repercussion of early-onset epilepsies on the immature brain is unquestionable, with sometimes very intense impairment of cognitive development. As a result, we make the following recommendations: early electro-clinical diagnosis, immediate treatment, timely change of medication if the seizures persist, avoid phenobarbital and valproate, and try other drugs or compounds that have proved to have neuroprotective effects in experimental studies.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Herranz JLsubject
Has Abstractpub_date
2007-05-21 00:00:00pages
S43-5eissn
0210-0010issn
1576-6578pii
rn2007232journal_volume
44 Suppl 3pub_type
杂志文章,评审abstract：INTRODUCTION:Diverse evidences have shown that the process of natural aging causes a decline in different cognitive functions, including among them the attentional process. AIM:To determine how the healthy aging affects to the different attentional networks. SUBJECTS AND METHODS:Two groups: young subjects (32.5 ± 9.7...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：INTRODUCTION:The subarachnoid haemorrhage non traumatic assumes between the 6-8% of all acute cerebrovascular, besides is more frequent in young persons. The mortility and mortality is high and the predictive factors of the worse prognostic in unknown. MATERIAL AND METHODS:In the present work, we realized a study of t...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：INTRODUCTION:'Sword stroke' linear scleroderma, which is better known as linear scleroderma en coup de sabre (LSCS), is a rare disease with an uncertain causation that is characterised by progressive craniofacial focal atrophy and is, at least in part, different from Parry-Romberg syndrome (PRS). CASE REPORTS:Here, we...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-11-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-09-01 00:00:00
abstract：INTRODUCTION:Both the normal and pathological development and involution of the CNS are regulated by an important set of both, 'growth factors' (inducing growth, differentiation, survival, adaptation or plasticity in neurons) and 'ageing factors' (inducing involution, atrophy, necrosis or apoptosis). In neurodegenerati...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1997-10-01 00:00:00
abstract：INTRODUCTION AND OBJECTIVE:The objective of the study was to analyze the EEG tracings during the seizures of two monozygotic twins, shown on molecular analysis, diagnosed as having infantile epilepsy with absences. The recordings are particularly interesting since the genotypes of the patients are identical. This allow...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-12-16 00:00:00
abstract：INTRODUCTION:Rett's syndrome (RS) is a disorder of neurological development which is the second commonest cause of mental retardation in girls. It is normally caused by de novo mutations of a gene on the X chromosome. This gene encodes for the protein joining the methyl CpG (MECP2). Mutations of this gene have been fou...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-02-01 00:00:00
abstract：INTRODUCTION:The Aragon Stroke Care Plan (PAIA) was created in 2008 within the framework of the Spanish National Health System. Monitoring hospital care of strokes by means of periodic audits was defined as one of its lines of work. AIM:To determine the quality of the hospital care process for stroke patients in Arago...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2016-07-16 00:00:00
abstract：INTRODUCTION:Unilateral isolated paralysis of the soft palate is a rare clinical entity. CASE REPORT:We describe the case of a 12 year old girl who presented acute dysphagia, a nasal voice and regurgitation of liquids into the nose. Exploration revealed right velopalatine insufficiency with normal gag reflex and phary...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2003-02-15 00:00:00
abstract：INTRODUCTION:Neurocystercicosis (NCC) is a disorder caused by the Taenia solium larva. It is the commonest parasitosis of the CNS. In Spain most patients are from countries where the condition is endemic. However, sporadic cases still occur amongst the non immigrant population of rural regions. We report a new case of ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-02-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-12-16 00:00:00
abstract：OBJECTIVE:We review the molecular basis of epileptogenesis and the new perspectives in the treatment of epilepsy. DEVELOPMENT:Epileptogenesis are the molecular and cellular events producing the disordered firing of a subpopulation of neurons resulting in periodic seizures. Epilepsies may be due to genetic and acquired...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-03-01 00:00:00
abstract：INTRODUCTION:Cysticercosis remain an important health problem in developing countries. Its transmission is related to soil contamination with human feces. This parasitosis is found in Africa, Asia and Latin America, where the greatest incidences are seen in Mexico and Brazil. DEVELOPMENT:Human cysticercosis is acquire...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-08-16 00:00:00
abstract：TITLE:Facilitar el acceso a toda la informacion debe ser una obligacion para las revistas medicas. : ...
journal_title：Revista de neurologia
pub_type： 信件
doi：
更新日期：2018-02-16 00:00:00
abstract：INTRODUCTION:Hyperekplexia is a disease characterized by an exaggerated startle reflex in front of minimal tactile and/or acoustic stimuli, that usually goes with high muscular tone, except when the patient is sleep. When the patient grows, high muscular tone decreases and then appear sudden hypertonic episodes that ma...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：INTRODUCTION:Progressive cerebral polidystrophy or Alpers syndrome is a clinico-pathological picture, with no specific biological marker, characterized by involvement mainly of the cerebral grey matter and which shows clinically as a rapidly progressive encephalopathy with intractable seizures, usually myoclonic. The t...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-12-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2000-12-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2009-04-16 00:00:00
abstract：INTRODUCTION:Trigeminal neuralgia due to vertebrobasilar dolichoectasia is an acquired disease whose true incidence is not known. Microvascular decompression is the most effective technique both for symptomatic relief and for the conservation of nerve structure and function, in spite of the potential complications of a...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-04-16 00:00:00
abstract：AIMS:We review one of the most important functional techniques in magnetic resonance imaging, perfusion MRI (pMRI) with emphasis in its applications, particularly in the diagnosis and follow up of brain lesions. First, we discuss the physical principles and results of the technique, then, we discuss its major applicati...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2010-01-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-06-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-02-16 00:00:00
abstract：INTRODUCTION:After Zika virus outbreak and the increase in the incidence of Guillain-Barre syndrome (GBS), the causal relationship has been studied, however a full etiological correlation has not been found. PATIENTS AND METHODS:From January 1 to December 31, 2017, patients with GBS were included. In addition to the b...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2018-09-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 信件
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更新日期：2014-06-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2012-04-16 00:00:00
abstract：INTRODUCTION:Technological advances have helped to lower the rate of infantile mortality and to raise the survival rate of preterm infants. Thus, studies need to be conducted in this segment of the population, while prematurity continues to be one of the risk factors for neuro-sensory-motor disorders. There is evidence...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:In order to evaluate the degree of neurological knowledge in a general practitioner (GP), and given the lack of a useful instrument with which to do so, we propose the drawing up of a neurological knowledge test which would give adequate psychometric guarantees. By using a broad-based sample of professionals working i...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 信件
doi：10.33588/rn.7011.2019333
更新日期：2020-06-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-10-01 00:00:00
abstract：INTRODUCTION:Many neuropsychological tests used in Spain have been normed on Spanish-speaking persons in the USA and South America. In addition, the normative samples often span limited age or educational ranges, potentially decreasing their representativeness of the population, the interpretation of test results, and ...
journal_title：Revista de neurologia
pub_type： 杂志文章,多中心研究
doi：
更新日期：2015-07-16 00:00:00
