Abstract：
AIMS:We review one of the most important functional techniques in magnetic resonance imaging, perfusion MRI (pMRI) with emphasis in its applications, particularly in the diagnosis and follow up of brain lesions. First, we discuss the physical principles and results of the technique, then, we discuss its major applications. DEVELOPMENT AND CONCLUSIONS:In clinical settings, two different contrast-based MRI techniques are used: T2*-weighted dynamic susceptibility contrast MRI (DSC) and T1-weighted dynamic contrast enhancement imaging (DCE). DSC measures the pharmacokinetics of first pass contrast bolus through a predefined volume. In contrast, DCE measures capillary permeability, derived it from an assumed compartment model in a time-series of T1-weighted images. The major usefulness of pMRI has been reported in brain tumors, brain ischemia and inflammation, and degenerative disorders. In this paper we review the physical basis and the contribution of MRI perfusion to the diagnosis and prognosis of several diseases of the central nervous system.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Fayed-Miguel N,Castillo-Blandino J,Medrano-Lin Jsubject
Has Abstractpub_date
2010-01-01 00:00:00pages
23-32issue
1eissn
0210-0010issn
1576-6578pii
rn2008363journal_volume
50pub_type
杂志文章,评审abstract：INTRODUCTION:The value of the P300 cognitive event-related potential in the diagnosis of Alzheimer subtype neurocognitive disorders is still incipient. Recent studies suggest that combining it with neuropsychological tests by cognitive domains would allow an objective and early characterisation of the cognitive impairm...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：10.33588/rn.7101.2019341
更新日期：2020-07-01 00:00:00
abstract：INTRODUCTION:Optogenetic is an experimental technique that combines genetic engineering and optical physics procedures to mark specific neurons in the brain and activate them at will through rays of light of certain frequency. AIM:To explain, to readers not versed in genetics the history, the rationale and the present...
journal_title：Revista de neurologia
pub_type： 历史文章,杂志文章
doi：
更新日期：2016-02-01 00:00:00
abstract：:Taking the characteristics of the ideal antiepileptic drug as the standard, the advantages and disadvantages of the drugs commercially available in recent years-vigabatrin, lamotrigin, gabapentin, and felbamate-are considered from the point of view of their mode of action, pharmacokinetic properties, therapeutic spect...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1996-11-01 00:00:00
abstract：INTRODUCTION:Alterations in SCN1A gene cause most cases of Dravet syndrome. This finding has increased scientific interest in the syndrome, helping to better define its clinical features and facilitating treatment. AIMS:To update the knowledge on Dravet syndrome and to discuss the role of the molecular studies in impr...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2011-06-01 00:00:00
abstract：INTRODUCTION:Early infantile epileptic encephalopathy (EIEE) with suppression burst activity in EEG (Ohtahara syndrome) is a rare type of epileptic encephalopathy in infancy and represents the earliest type of age-related symptomatic generalized epilepsy. The main etiologic factors associated to EIEE are cerebral dysge...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：OBJECTIVE:The author reviews the value of the electrophysiological techniques: electromyography (EMG), electroneurography or motor and sensitive nerve conduction velocity (MCV, SCV), brainstem auditory potentials (BAER), visual evoked potentials (VEP) and electroretinography (ERG), somatosensory evoked potentials (SEP)...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
abstract：TITLE:Hematoma subdural cronico calcificado: cerebro blindado. : ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2014-05-01 00:00:00
abstract：INTRODUCTION:In the evaluation of stenoses of the extracranial internal carotid artery (ICA), there are studies that suggest that magnetic resonance angiography (MRA) can be a substitute for conventional arteriography (CA), although it seems it has a tendency to overestimate the degree of stenosis. No similar compariso...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-10-16 00:00:00
abstract：INTRODUCTION:Lyme disease is a complex infectious disease affecting multiple organic systems. The most frequent complications are of a dermatological, rheumatological, ophthalmological, cardiac and neurological nature. Among the neurological complications, pseudotumour cerebri is considered to be a rare manifestation o...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-04-16 00:00:00
abstract：INTRODUCTION:Arachnoid cysts are cavities with a content similar to cerebrospinal fluid, frequently communicating with the subarachnoid space. They make up 1% of the intracranial space occupying lesions, and although typically seen in children (13%), they may be undiagnosed until the patient has become adult. PATIENTS...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-08-16 00:00:00
abstract：INTRODUCTION:Epilepsy is one of the most common neurological disorders, affecting about one percent of the world population. Pharmacological treatment fails in one-third of these patients. Surgical intervention has become an accepted treatment option for those patients with seizure disorders that are refractory to conv...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1998-10-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 共识发展会议,杂志文章,实务指引
doi：
更新日期：2009-09-16 00:00:00
abstract：INTRODUCTION:The retina is a neuronal membrane that covers the posterior part of the eye chamber and is formed by several layers. The retinal function can be synthesize as the light translation into nervous impulses in the optic nerve. MATERIAL AND METHODS:The ERG is the expression of the changes of the electrical pot...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1998-03-01 00:00:00
abstract：INTRODUCTION:There is now growing evidence that essential tremor and Parkinson's disease are related. AIM:To present the main findings from epidemiologic, genetic, clinical, imaging and pathologic studies, contrasting evidences for and against an association between essential tremor and Parkinson's disease. DEVELOPME...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2012-10-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2017-02-16 00:00:00
abstract：INTRODUCTION:Restless legs syndrome (RLS) is a usual neurologic disorder, often undiagnosed and treatable, usually associated with sleep disturbance. Our goal was to study prevalence of RLS in our practice. PATIENTS AND METHODS:Descriptive, cross-sectional study, in a Primary care center. 283 patients 50 years old or ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-06-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-12-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：TITLE:Respuesta favorable al uso de inmunoglobulinas intravenosas en la mielinolisis central pontina. : ...
journal_title：Revista de neurologia
pub_type： 信件
doi：
更新日期：2013-08-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-08-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2010-12-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-02-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2004-09-16 00:00:00
abstract：INTRODUCTION:Neurotoxoplasmosis (NTX) is one of the commonest opportunist infections in patients infected by the human immunodeficiency virus. It presents with a variety of clinical features in the immunocompromised patient. PATIENTS AND METHODS:We made a horizontal retrospective descriptive study of 88 patients with ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-04-01 00:00:00
abstract：INTRODUCTION:In recent years, significant advances have been made in the physiology and the pharmacology of vestibular disorders. It is now possible to elaborate an approximation of the mechanisms of action of the drugs used in the symptomatic treatment of vertigo. DEVELOPMENT:These drugs usually have a number of diff...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2004-08-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2007-12-01 00:00:00
abstract：:By means of the modified trichromic method of Gomori, introduced by Engel and Cunningham in 1963 [1], it has been possible to demonstrate the presence of ragged-red fibers (RRF) in the mitochondrial myopathies. At present, to study these disorders in muscle biopsies, one may also use morphological, ultrastructural, hi...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1998-04-01 00:00:00
