Abstract:
INTRODUCTION AND DEVELOPMENT:The paraneoplastic neurological syndromes are alterations associated with neoplasias. However, they are not caused by metastases or complications such as infections, vascular disorders, metabolic or nutritional alterations or secondary effect of treatment. The paraneoplastic syndromes are often associated with the creation of autoantibodies against antigens produced by the neoplastia, but also may be against other cells or target molecules of the patient. Sometimes, especially with antibodies directed against cell membrane proteins, there is a close relationship between the antibody and the target organ, as for example antibodies against the acetylcholine receptor in myasthenia gravis. On other occasions, especially when the antigen is intracellular, the mechanism of the autoantibody reaction is not known. Finally, in a third group, the antibody associated with a particular paraneoplastic neurological alteration has not been identified. In this paper we describe the main paraneoplastic neurological pictures and known antibodies, including the molecular aspects and the neoplasias most frequently related to them.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Ferrer Isubject
Has Abstractpub_date
2000-12-16 00:00:00pages
1228-36issue
12eissn
0210-0010issn
1576-6578journal_volume
31pub_type
杂志文章,评审abstract:TITLE:Parálisis súbita de la supraversión de la mirada en una niña de 9 años. : ...
journal_title:Revista de neurologia
pub_type: 信件
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更新日期:2020-11-16 00:00:00
abstract:INTRODUCTION:Sneddon syndrome is the association of livedo retricularis and cerebrovascular lesions. It is a vasculopathy of vessels of small and medium calibre which affects young people and is of unknown origin. It is often associated with arterial hypertension and repeated ischemic cerebrovascular accidents which le...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract:INTRODUCTION AND AIMS:Mental retardation (MR) affects approximately 2-3% of the general population and around 75% of the known causes of MR are thought to have a genetic origin. The aim of this work is to describe a standardised model of diagnostic approach to patients with mental retardation of a genetic origin (MRGO)...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-01-07 00:00:00
abstract:INTRODUCTION:Adrenoleukodystrophy is a hereditary recessive sex-linked disorder with very variable phenotype expression, including classical infantil ALD, adrenomyeloneuropathy (AMN) in adults and sex-linked Addison's disease. Clinical observations. Three affected patients are presented. The first showed signs of myelo...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract:INTRODUCTION:Since description of the expansion of the number of CTG trinucleotides on the long arm of chromosome 19 in the 19 q 13.2-13.3 interval as being responsible for myotonic dystrophy (DM), many studies have established a direct relationship between the size of the expansion and the severity of the manifestatio...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-09-16 00:00:00
abstract::We have carried out an overall analysis of the diagnostic approach to generalized epileptic crises in children. It is emphasized that the clinical history is an essential factor in reaching the correct diagnosis. This is inevitably followed by a general and then a specifically neurological physical examination. Four p...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1998-02-01 00:00:00
abstract:INTRODUCTION:The presence of quick onset binocular diplopy makes it essential to carry out a comprehensive differential diagnosis. The most frequent causes in adults include vascular, post-traumatic, tumorous and myopathic pathologies. Yet, to perform a differential diagnosis we also have to take into account less comm...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-06-16 00:00:00
abstract:TITLE:SARS-CoV-2, nuevo agente causal del síndrome de Guillain-Barré. ...
journal_title:Revista de neurologia
pub_type: 信件
doi:10.33588/rn.7107.2020264
更新日期:2020-10-01 00:00:00
abstract::INTRODUCTION. Dystrophinopathies are X-linked genetic disorders caused by mutations in the DMD gene. Genetic tests are of utmost importance for management and genetic counseling of these diseases. However, the complexity of the DMD gene is a challenge for diagnosis. AIM. To describe recent advances in the diagnosis of...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2011-02-16 00:00:00
abstract:AIM:To analyze the safety profile and clinical outcome of patients with acute cerebral ischemia who received open treatment with tissue plasminogen activator (rt-PA) in a hospital without previous experience. PATIENTS AND METHODS:This prospective and observational study were realized from January 2004 to January 2007....
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the therapeutic response of West's syndrome (WS) associated with cerebral paralysis (CP) secondary to periventricular leucomalacia (PVL). MATERIAL AND METHODS:We made a retrospective analysis of the clinical histories of 10 patients with SW and CP secondary to periventricular leucomalacia. We stu...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:INTRODUCTION:The development of scientific advances, constantly opening new frontiers of knowledge, leads to increasing complexity and specialization. DEVELOPMENT:The conflict between the never ending medical specialization and the opposite tendency, which is based mostly on economic grounds, prevents the acquisition ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract:INTRODUCTION:Valproic acid (VPA) is a useful antiepileptic drug for controlling different types of epilepsy. It has several side effects and is associated to increased body weight, as well as metabolic and endocrine disorders, including metabolic syndrome. AIM:To determine the prevalence of obesity and metabolic syndr...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2015-09-01 00:00:00
abstract:INTRODUCTION:The term 'frontotemporal lobar dementia' (FTLD) covers a group of neurodegenerative diseases that are very heterogeneous in their clinical expression, genetic component and histopathological features, and this has traditionally made it difficult to study and classify them. Patients usually present a progre...
journal_title:Revista de neurologia
pub_type: 历史文章,杂志文章,评审
doi:
更新日期:2008-12-01 00:00:00
abstract::Unfortunately, in spite of the advances in foetal and perinatal medicine in the last twenty years, the incidence of cerebral palsy has remained unchanged (1.5-2.5 per 1000 live births). It has even possibly risen slightly in premature babies of low birth weight, in parallel with the increased survival of these babies....
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1997-05-01 00:00:00
abstract:INTRODUCTION:Cystinosis is a hereditary disease with clinical symptoms that are caused by the accumulation of cystine crystals in different tissues. Distal vacuolar myopathy has been reported as one of its later complications. CASE REPORT:Here, we present the case of a 20-year-old male diagnosed with cystinosis at the...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-02-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:The treatment of non traumatic intra cerebral haemorrhage is one of the therapeutic challenges at the present time. In spite of present day technology and advances in understanding its physiopathology, the prognosis is the same as it was fifteen years ago. We review the surgical treatments us...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2001-06-01 00:00:00
abstract:INTRODUCTION:An arterial gas embolism is defined as the presence of air in the arterial circulation. This is an extremely rare cause of stroke that has been described in a multitude of clinical scenarios, generally related to iatrogenic processes. A clinical case is reported in which the arterial gas embolism occurred ...
journal_title:Revista de neurologia
pub_type:
doi:10.33588/rn.6903.2019178
更新日期:2019-08-01 00:00:00
abstract:AIMS:In the search for new, potentially treatable, vascular risk factors, one of the most recent to be put forward is the presence of increased total homocysteine (tHc) levels in blood plasma and this has also given rise to a large amount of literature and controversy. The origin of this hypothesis lies in the observat...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2004-02-16 00:00:00
abstract:AIM:To analyse the data and concepts that have been produced in relation to one of the functions that have been suggested for sleep, namely, neuronal recovery. DEVELOPMENT:Sleep is a state of consciousness that is different to that of arousal. Mammals devote an important part of their lives to sleeping; for example, a...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-10-01 00:00:00
abstract:INTRODUCTION:Diverse evidences have shown that the process of natural aging causes a decline in different cognitive functions, including among them the attentional process. AIM:To determine how the healthy aging affects to the different attentional networks. SUBJECTS AND METHODS:Two groups: young subjects (32.5 ± 9.7...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:The endocannabinoid system consists of cannabinoid receptors, endogenous ligands and the enzymatic elements involved in their synthesis and breakdown. AIM:To report on currently held knowledge about the functioning of the system as a modulator of the neuroinflammatory processes associated with chronic dis...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-11-01 00:00:00
abstract:INTRODUCTION:Advances in neuroimaging in the last decade have allowed a number of new findings about attention deficit hyperactivity disorder (ADHD) to be obtained. Quickly developing technology, together with the progress being made in genetics and neurochemical research, suggests a dysfunction of the fronto striatal ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2010-03-03 00:00:00
abstract:TITLE:42.ª Reunion de la Sociedad de Neurofisiologia Clinica de las Comunidades de Valencia y Murcia. Comunicaciones. : ...
journal_title:Revista de neurologia
pub_type:
doi:
更新日期:2017-12-01 00:00:00
abstract:INTRODUCTION:In the treatment of speech disorders by means of speech therapy two antagonistic methodological approaches are applied: non-verbal ones, based on oral motor exercises (OME), and verbal ones, which are based on speech processing tasks with syllables, phonemes and words. In Spain, OME programmes are called '...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2016-01-01 00:00:00
abstract:INTRODUCTION:Subacute sclerosing panencephalitis (SSPE) is a chronic neurodegenerative disease secondary to an infection of the central nervous system by the measles virus, with no effective treatment. The introduction of therapy with intraventricular interferon alpha (IFN-alpha) and its later association with ribaviri...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2006-03-01 00:00:00
abstract:: TITLE:Sindrome de Guillain-Barre en tiempos de arbovirosis. ...
journal_title:Revista de neurologia
pub_type: 评论,信件
doi:
更新日期:2018-12-01 00:00:00
abstract:INTRODUCTION:Trigeminal neuralgia due to vertebrobasilar dolichoectasia is an acquired disease whose true incidence is not known. Microvascular decompression is the most effective technique both for symptomatic relief and for the conservation of nerve structure and function, in spite of the potential complications of a...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-04-16 00:00:00
abstract:AIM:The aim is to review the molecular and genetic aspects of the dystrophic and no dystrophic myotonias. BACKGROUND:Myotonic diseases are hereditary conditions of the skeletal muscle, classified in two groups depending on the symptoms. In the first group are the myotonic dystrophies, with the myotonic dystrophies typ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2004-04-01 00:00:00
abstract:INTRODUCTION:Genetic etiology in suggested in intracranial aneurysms. Such hypothesis is supported on familial aggregation, ocurrence in identical twins or associated to genetic diseases like adult polycystic renal disease. OBJECTIVE:To identify biological features in familial aneurysms different to sporadic ones. PA...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-02-01 00:00:00