Abstract:
BACKGROUND:Mechanic's hand is a defined specific skin eruption associated with dermatomyositis; there are few reports concerning its histopathology. As mechanic's hand clinically resembles hand eczema, it is important to distinguish between these two conditions. AIM:To determine the characteristic clinical and histopathologic features of mechanic's hand, and to clarify whether these two conditions can be differentiated by histopathologic findings. METHODS:We analyzed clinicopathologically five patients with mechanic's hands who visited our clinic between 2006 and 2007. RESULTS:The clinical features of mechanic's hands were discrete hyperkeratotic erythema on the ulnar aspect of the thumbs and the radial aspect of the fingers. In all five cases, the histologic findings included marked hyperkeratosis, focal parakeratosis, psoriasiform acanthosis, and colloid bodies in the epidermis. There were mononuclear cell infiltrates around the blood vessels, and mucin deposition was observed in the dermis. CONCLUSIONS:The histopathologic findings of mechanic's hands are specific and different from those of eczema. A histopathologic examination is useful for the diagnosis of mechanic's hands associated with dermatomyositis and a high incidence of interstitial pneumonia.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Mii S,Kobayashi R,Nakano T,Harada H,Okada M,Matsui Y,Fujii T,Eto Hdoi
10.1111/j.1365-4632.2009.04164.xsubject
Has Abstractpub_date
2009-11-01 00:00:00pages
1177-82issue
11eissn
0011-9059issn
1365-4632pii
IJD4164journal_volume
48pub_type
杂志文章abstract:BACKGROUND:Most cutaneous tuberculosis lesions contain few bacilli, so identification of Mycobacterium tuberculosis in conventional laboratory tests is difficult. In vitro amplification of specific DNA sequences using polymerase chain reaction (PCR) has become a valuable tool in the rapid detection of slow-growing orga...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2002.01604.x
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abstract::Actinic keratosis (AK) is a very common skin disease caused by chronic sun damage, which in 75% of cases arises on chronically sun-exposed areas, such as face, scalp, neck, hands, and forearms. AKs must be considered an early squamous cell carcinoma (SCC) for their probable progression into invasive SCC. For this reas...
journal_title:International journal of dermatology
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abstract::The care of breast cancer patients is important to dermatologists. Breast cancer's initial presentation, clinical progression, and its associated treatments can result in a variety of cutaneous complications. Dermatologists may be the first to identify a breast cancer diagnosis, as a subset of patients first present w...
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abstract:BACKGROUND:Leishmania coinfection is frequently seen in human immunodeficiency virus (HIV)-infected patients in endemic areas, and from time to time the protozoan is detected in cutaneous biopsies. OBJECTIVE:To establish the characteristics and possible ethiologic role of the presence of Leishmania in these lesions. ...
journal_title:International journal of dermatology
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doi:10.1046/j.1365-4362.2002.01610.x
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abstract::In December of 2002, the FDA approved azelaic acid 15% gel for the topical treatment of inflammatory papules and pustules of mild to moderate rosacea. Azelaic acid is a saturated dicarboxylic acid, which is naturally occurring and has been used in the treatment of rosacea, acne, and melasma. The 15% gel has a high eff...
journal_title:International journal of dermatology
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abstract::A 23-year-old man presented with a diffuse and fine wrinkling of the skin of his back and trunk. Skin lesions had first appeared about 5 years earlier and resulted from coalescing of multiple, flat, pinkish-red papules, a few millimeters in diameter. A diagnosis of widespread cutaneous elastic hamartoma was made. Hist...
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abstract:BACKGROUND:Ayurvedic medicines are known to contain arsenic and concentrations up to toxic levels have been reported in certain formulations. However, clinical disease due to arsenic containing ayurvedic medicines has rarely been reported. We seek to highlight the existence of toxic levels of arsenic in certain ayurved...
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abstract:BACKGROUND:People with albinism (PWA) are targets of prejudice and social exclusion and have limited access to specialized medical care and resources. Our study aimed to describe the epidemiological and dermatological profile of PWA in Togo. METHOD:We carried out a cross-sectional study of 294 medical records of PWA s...
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abstract:BACKGROUND:Histoid leprosy (HL) is a highly bacilliferous form of leprosy which requires early diagnosis and management. Dermoscopy is a noninvasive diagnostic method for various malignant and nonmalignant disorders. The aim of this study was to describe the dermoscopic patterns of various types of HL lesions over diff...
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journal_title:International journal of dermatology
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journal_title:International journal of dermatology
pub_type: 杂志文章
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更新日期:1988-09-01 00:00:00
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journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1046/j.1365-4362.2000.00995.x
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journal_title:International journal of dermatology
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journal_title:International journal of dermatology
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journal_title:International journal of dermatology
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journal_title:International journal of dermatology
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更新日期:2010-01-01 00:00:00
abstract::The authors collected data from the literature and from experts on the subject of vaccination of patients with dermatologic disorders. They assembled these data into categories of specific skin conditions and vaccinations. These data may be used in deciding whether or not to vaccinate, and at which stage of the dermat...
journal_title:International journal of dermatology
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更新日期:2015-12-01 00:00:00