Abstract:
:In December of 2002, the FDA approved azelaic acid 15% gel for the topical treatment of inflammatory papules and pustules of mild to moderate rosacea. Azelaic acid is a saturated dicarboxylic acid, which is naturally occurring and has been used in the treatment of rosacea, acne, and melasma. The 15% gel has a high efficacy and is generally well tolerated, with the local irritation (burning, stinging, itching, and scaling) being typically mild and transient. Azelaic acid 15% gel is considered effective and safe as a therapy for inflammatory papulo-pustular rosacea and is suitable for use on all skin types.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Gupta AK,Gover MDdoi
10.1111/j.1365-4632.2005.02769.xsubject
Has Abstractpub_date
2007-05-01 00:00:00pages
533-8issue
5eissn
0011-9059issn
1365-4632pii
IJD2769journal_volume
46pub_type
杂志文章,评审abstract:BACKGROUND:The sicca syndrome has been defined as the occurrence of xerostomia and xerophthalmia. Sjögren's syndrome is the most common cause of the sicca syndrome; however, these two syndromes are not synonymous and there are many potential etiologies of the sicca syndrome. A less known cause of sicca syndrome is amyl...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1996.tb03653.x
更新日期:1996-08-01 00:00:00
abstract::Clinical, histologic, and immunofluorescence studies were performed in 15 patients with pemphigus herpetiformis. The initial diagnosis was dermatitis herpetiformis, IgA linear bullous dermatosis or bullous pemphigoid. The histology varied depending on the character of skin lesions, and showed eosinophilic spongiosis o...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1987.tb02308.x
更新日期:1987-11-01 00:00:00
abstract:BACKGROUND:Actinic prurigo (AP) is a photodermatosis with a restricted ethnic distribution, mainly affecting Mestizo women (mixed Indian and European). The lesions are polymorphic and include macules, papules, crusts, hyperpigmentation and lichenification. Thalidomide, an effective immunomodulatory drug, was first used...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02274.x
更新日期:2004-12-01 00:00:00
abstract::Methicillin-resistant Staphylococcus aureus (MRSA) infections occurring within communities are increasing and can affect healthy individuals who have had little to no experience with hospital or healthcare settings (community-associated MRSA, CA-MRSA). CA-MRSA infections have multiple presentations which can make diag...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.13010
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:To assess the safety and efficacy of a 0.005% mixture of solasodine glycosides (Zycure) in the treatment of basal cell carcinoma. Design Double-blind, randomized, and vehicle-controlled, parallel group study. SETTING:Ten centers in the United Kingdom. Participants Male, n = 50; female, n = 44; age range, 32-...
journal_title:International journal of dermatology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1365-4632.2007.03363.x
更新日期:2008-01-01 00:00:00
abstract::The correlation between combined chemotherapy, including 6-mercaptopurine, and development of excessive number of melanocytic nevi in childhood has been previously reported and studied. As of yet, no such relation has been reported in adults. We recently observed a 27-year-old female patient who developed numerous ben...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2005.02086.x
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:Regulatory T cells (Tregs) play an important role in autoimmune diseases. In skin, the presence of Tregs is thought to be mandatory for suppression of autoreactive T cells. Here, we assess the number of Tregs in skin of healthy subjects and patients with an autoimmune dermatosis. METHODS:Immunohistochemical...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2012.05808.x
更新日期:2014-03-01 00:00:00
abstract::Demodecidosis is an ectoparasitosis that is infrequently observed in subjects with human immunodeficiency virus (HIV) infection. It has a rosacea-like presentation. We present three cases in patients with acquired immunodeficiency syndrome (AIDS). Two of these patients had a profuse eruption, and all three cases were ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2006.02924.x
更新日期:2006-09-01 00:00:00
abstract::Netherton syndrome is a rare disorder inherited in an autosomal recessive pattern consisting of ichthyosiform dermatosis, hair shaft abnormalities (trichorrhexis invaginata), and an atopic diathesis. Patients with Netherton syndrome have been found to have a mutation on chromosome 5q32 in a gene named SPINK5 (serine p...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4632.2005.02637.x
更新日期:2006-06-01 00:00:00
abstract::Health authorities in the USA, Canada and Australia recommend a "no nit" policy, i.e. the immediate dismissal of all children who have head lice, eggs and/or nits on their hair from school, camp or child-care settings. These children would be readmitted to the institution only when all head lice, eggs and nits have be...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4632.2006.02827.x
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVES:Oral lichen planus (OLP) is a chronic inflammatory disease of unknown cause. Malignant transformation in OLP lesions may be favored by changes in the expression of proteins that regulate cell proliferation and apoptosis. This study aimed to investigate these issues by immunohistochemical staining for Bcl-2 a...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12279
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Recent studies have implicated the association between oxidative stress and inflammation in pathogenesis of psoriasis and its associated comorbidities. Hence, we undertook to study inflammatory markers such as sialic acids and the oxidative stress index (OSI) in patients with psoriasis vulgari...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13196
更新日期:2016-08-01 00:00:00
abstract::Hydroxyurea is a hydroxylated derivate of urea commonly used in the treatment of various hematologic disorders. Cutaneous side-effects such as alopecia, diffuse hyperpigmentation, scaling, poikiloderma, atrophy of the skin and subcutaneous tissues or nail changes can develop after long-term treatment with hydroxyurea....
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02450.x
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:To assess the efficacy and safety of topical 5% cysteamine versus 4% hydroquinone in the treatment of facial melasma in women. Topical 5% cysteamine is an antioxidant and tyrosinase inhibitor that has been shown to be effective in the treatment of melasma. However, to date, no study has compared the performan...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.15146
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Vitiligo is a common disorder whose exact cause is unknown, but genetic factors are thought to be involved. We analyzed 120 Korean proband families to clarify which genetic factors are involved in the pathogenesis of vitiligo in Korean patients. METHODS:The genetics of vitiligo were analyzed in 120 Korean p...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.1998.00549.x
更新日期:1998-12-01 00:00:00
abstract::An 11-month-old male infant was referred to our clinic because of a painful ulcer of approximately 5 months' duration on the ventral surface of the tongue (Fig. 1). On physical examination, the lesion was circular (3 cm x 2 cm) with erythematous, raised, and indurated borders. No pathologic findings emerged from the l...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02554.x
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Different studies have shown a high prevalence of Helicobacter pylori (HP) infection in patients with chronic urticaria (CU), and occasional remission of the skin lesions after eradication therapy. Recent investigations, however, have failed to find a significant relationship between the two conditions. We d...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1046/j.1365-4362.2000.00995.x
更新日期:2000-06-01 00:00:00
abstract::Vegetable oils have been used for a wide variety of purposes since time immemorial; however, their principle use remains as skin moisturizers, especially in neonates and children. Because of their considerable efficacy and a low side effect profile and bearable cost, these oils are hugely popular as moisturizers among...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.13623
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Tinea capitis is a dermatophyte infection of the scalp, eyebrows, and eyelashes caused by species of Microsporum and Trichophyton. The purpose of this study was to discover the incidence and causal agents of tinea capitis in Saudi Arabia. METHODS:Hair roots, skin scrapings, and pus swabs were collected from...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1993.tb00961.x
更新日期:1993-01-01 00:00:00
abstract::The response of 47 chronic ulcers (41 neuropathic [leprosy], 3 stasis, 1 traumatic, and 2 of unknown etiology) to hydrocolloid occlusive dressings was evaluated at a rural south Indian hospital. The response to treatment was objectively evaluated by photographic estimation of the surface areas of the ulcers. Eight ulc...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1988.tb04931.x
更新日期:1988-04-01 00:00:00
abstract:BACKGROUND:Targeted therapies and immunotherapies are increasingly prescribed, but classic chemotherapy agents are still highly used in cancer treatment. Both therapies, the old and the new, are associated with cutaneous adverse events (CAEs) that can cause treatment interruptions or reduce the quality of life of patie...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.15081
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Antitumor necrosis factor (anti-TNF) agents are a well-established treatment for various medical conditions, including psoriasis and psoriatic arthritis. However, anti-TNF agents may themselves induce psoriasis in some patients. METHODS:The authors report two cases of patients with severe and refractory inf...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2012.05601.x
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Exposure to sunlight is an important etiologic factor in cutaneous melanoma (CM). In several countries, more cases of CM are diagnosed in summer than in winter. AIM:To analyze whether there is seasonal variation in the diagnosis of CM in southern Brazil. METHODS:Data were collected from a hospital-based re...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2009.04174.x
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Tick bites are dermatoses not commonly encountered in Korea. Recognizing their clinical signs as well as their histopathologic findings is important in making a diagnosis of tick-related dermatoses. The incidence and causative species are different depending on the geographic areas. The histopathologic findi...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4362.1994.tb02894.x
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:Primary cutaneous cryptococcosis is an uncommon infectious disease caused by Cryptococcus neoformans or Cryptococcus gattii affecting immunosuppressed as well as immunocompetent patients. It is often misdiagnosed as it may mimic other cutaneous diseases. MATERIALS AND METHODS:We report a series of cases dia...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2011.05298.x
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Epidemiological studies of molluscum contagiosum (MC) in children are limited. PATIENTS AND METHOD:Between 1997 and 1999, 110 children with MC (60 boys, 50 girls, mean age: 4.8 years) were studied. Treatment consisted of removal of all MC lesions in a single session by sterilized tweezers. RESULTS:In child...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02074.x
更新日期:2005-03-01 00:00:00
abstract::A double-blind study of 30 patients with mild to moderate acne vulgaris was conducted to evaluate the efficacy of a topically applied 2% zinc sulfate solution for acne therapy. Over a 12-week period, no difference was noted between placebo- and zinc-treated participants in regard to either the number or type of acne l...
journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章
doi:10.1111/j.1365-4362.1985.tb05756.x
更新日期:1985-04-01 00:00:00
abstract:BACKGROUND:Self-reported complaints in people having tattoos, including swelling, itch, and photosensitivity, are frequent. Tattooists are usually heavily tattooed with multiple extended colored tattoos and constitute a specific population of interest. OBJECTIVES:To assess the prevalence of cutaneous complications on ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13030
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Bullous skin diseases are known to be associated with significant morbidity and mortality. There have been no studies on mortality from severe bullous skin diseases in Canada. METHODS:We used mortality data from the Statistics Canada website from 2000 to 2007 for three major bullous skin diseases: bullous p...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2011.05227.x
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:Onychomycosis, a fungal infection of the nail, is caused by dermatophytes, yeasts, and nondermatophyte molds. The causative pathogen and incidence of onychomycosis depend on age, gender, geographic and climatic conditions, living habits, and immune status of the host. AIM:To determine the incidence and etio...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2009.04126.x
更新日期:2009-09-01 00:00:00