Abstract:
:Papular pruritic eruption (PPE) is a frequent HIV-comorbidity in tropical countries. Because of constant itching and social stigma, effective treatment is highly valued. In our HIV cohort in rural Tanzania with 12% prevalence of PPE, we have retrospectively analyzed responses to available treatments. Oral promethazine improved itching (P < 0.0058) and clinical scores (P < 0.032) significantly more than topical steroids. Disease activity did not correlate with CD4+ and CD8+ T cell counts and was independent of anti-retroviral medication. Therefore, oral antihistamines are an effective first-line treatment for PPE.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Navarini AA,Stoeckle M,Navarini S,Mossdorf E,Jullu BS,Mchomvu R,Mbata M,Kibatala P,Tanner M,Hatz C,Schmid-Grendelmeier Pdoi
10.1111/j.1365-4632.2009.04279.xsubject
Has Abstractpub_date
2010-01-01 00:00:00pages
83-6issue
1eissn
0011-9059issn
1365-4632pii
IJD4279journal_volume
49pub_type
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journal_title:International journal of dermatology
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