Comparative immunological analysis of innate immunity activation after oral administration of wheat fermented extract to teleost fish.

abstract：:Valproic acid (VPA) has been considered as a possible treatment agent for malignant gliomas. In order to characterise the possibilities of VPA, we investigated the effects on cell migration and proliferation. Human cell lines T98G, A172, 85HG66 and 86HG39 were treated with VPA or left untreated, afterwards Boyden cham...

journal_title：Anticancer research

authors： Knüpfer MM,Pulzer F,Schindler I,Hernaíz Driever P,Knüpfer H,Keller E

更新日期：2001-01-01 00:00:00

abstract：:An in vitro pilot study was conducted of the possible utility of combining low doses of cytosine arabinoside (araC) and GM-CSF to stimulate leukemic cell differentiation. Cytosine arabinoside induced macrophage differentiation in some cultures but only when the drug produced substantial cytostatic effects. GM-CSF, whe...

journal_title：Anticancer research

authors： Gao XZ,Yin MY,Preisler HD

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:The secretory epithelial cells of the prostate gland use sophisticated vehicles in the form of prostasomes to relay important information to sperm cells in semen. This prostasome-forming and secretory ability of the epithelial cells is also preserved in poorly differentiated prostate cancer cells. The aim of...

journal_title：Anticancer research

authors： Ronquist KG,Ronquist G,Larsson A,Carlsson L

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Adjuvant immunotherapy with interferon alpha in non-metastatic RCC is still controversial. It was the aim of the present study to investigate whether tumor ploidy can help to isolate a group of patients profitting from this treatment. MATERIALS AND METHODS:Survival data of 119 patients undergoing tumor neph...

journal_title：Anticancer research

authors： Basting R,Corvin S,Händel D,Hinke A,Schmidt D

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Docetaxel is a well tolerated chemotherapy for non-small cell lung cancer (NSCLC). However, few studies have investigated interstitial lung disease (ILD) associated with docetaxel. The purpose is to describe the incidence of this complication by using NSCLC patients. PATIENTS AND METHODS:Between September 2...

journal_title：Anticancer research

authors： Tamiya A,Naito T,Miura S,Morii S,Tsuya A,Nakamura Y,Kaira K,Murakami H,Takahashi T,Yamamoto N,Endo M

更新日期：2012-03-01 00:00:00

abstract：:MUC1 (DF3 antigen) is a member of a family of high molecular weight glycoproteins. Recent studies have demonstrated that MUC1 is expressed in tumors of various human organs and may function as an anti-adhesion molecule that inhibits cell-to-cell adhesion, inducing tumor metastasis. However, expression patterns of MUC1...

journal_title：Anticancer research

authors： Kijima H,Chino O,Oshiba G,Tanaka H,Kenmochi T,Kise Y,Shimada H,Abe Y,Tokunaga T,Yamazaki H,Nakamura M,Tanaka M,Makuuchi H,Ueyama Y

更新日期：2001-03-01 00:00:00

abstract：:The effect of 4,6-benzylidene-D-glucose (BG) on chemically induced primary hepatocellular carcinomas in rats was tested after daily single injections of 85 mg per kg body weight into the aorta through a canula implanted through the right carotid artery. Treatment started immediately following a biopsy confirming the d...

journal_title：Anticancer research

authors： Pettersen EO,Schwarze PE,Dornish JM,Nesland JM

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Mitoxantrone resistance has been related to the expression of a drug efflux pump breast cancer resistance pump (BCRP) but little is known of the intracellular protein changes. In this work, differential protein expression in a squamous lung carcinoma cell line, DLKP, and its mitoxantrone-resistant variant (D...

journal_title：Anticancer research

authors： Murphy L,Clynes M,Keenan J

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Chagas disease patients with longstanding megaesophagus have a significantly increased risk for esophageal carcinoma. MATERIALS AND METHODS:PCR-SSCP analysis and DNA sequencing of esophageal mucosa from Chagas disease patients (with or without megaesophagus) in the exons of the TP53, CDKN2A and FHIT genes w...

journal_title：Anticancer research

authors： DA Silva Manoel-Caetano F,Silveira AF,Silva AE

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:For eradicating portal venous tumor extension and intrahepatic metastasis in hepatocellular carcinoma (HCC), anatomical resection is, in theory, preferable. PATIENTS AND METHODS:We carried-out a retrospective cohort study in 110 patients who underwent curative hepatic resection (anatomical resection; n=20, ...

journal_title：Anticancer research

authors： Yamashita Y,Imai D,Bekki Y,Takeishi K,Tsujita E,Ikegami T,Yoshizumi T,Ikeda T,Shirabe K,Ishida T,Maehara Y

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND/AIM:The aim of the present study was to clarify if the degree of hepatic infiltration and lymph node swelling of gallbladder carcinoma (GBC) should be held as deciding factors for T2-4 GBC patients to undergo surgery. PATIENTS AND METHODS:Fifty consecutive patients with T2-4 GBC who underwent surgery were r...

journal_title：Anticancer research

authors： Okada K,Kawai M,Ueno M,Hirono S,Miyazawa M,Hayami S,Shimizu A,Shigekawa Y,Kitahata Y,Miyamoto A,Yamaue H

更新日期：2016-06-01 00:00:00

abstract：:Two experiments were performed with a chemically induced hepatoma in the rat. In the first, tumors were inoculated subcutaneously into both flanks. After 10 days, when all rats had tumors, treatment was given intravenously on two successive days with 10 mg carmustine/kg body weight/day. All control rats displayed grow...

journal_title：Anticancer research

authors： Roos G,Stenram U

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:CD98 expression is high in various human neoplasms. However, the relationship of CD98 expression with the clinicopathological factors of gastric cancer (GC) remains unclear. This study examined CD98 expression and its clinicopathological impact on GC. PATIENTS AND METHODS:Three hundred and thirty-one patien...

journal_title：Anticancer research

authors： Satoh T,Kaira K,Takahashi K,Takahashi N,Kanai Y,Asao T,Horiguchi J,Oyama T

更新日期：2017-02-01 00:00:00

abstract：:The objective of this study was to discover whether the peptides LRMK and LRMK-Ava linked to the N-terminus of peptides HER-2 (774-788) and HER-2 (776-788), respectively, help differentiation of E75-TCR(+)CD8(+) cells. Activation was quantified in terms of proliferation of E75-TCR(+)CD8(+) cells expressing high, mediu...

journal_title：Anticancer research

authors： Matsueda S,Gao H,Efferson CL,Tsuda N,Ishiyama S,Li Y,Ioannides MG,Fisk B,Peoples GE,Ioannides CG

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND/AIM:5-Aminolevulinic acid (5-ALA), a precursor of protoporphyrin IX (PpIX), is now used for photodynamic therapy (PDT) of pre-cancers of the skin and photodynamic diagnosis (PDD) of brain tumors. Sonodynamic therapy (SDT) of cancers with ultrasound has been studied using 5-ALA as a sonosensitizer. In this ar...

journal_title：Anticancer research

authors： Shimamura Y,Tamatani D,Kuniyasu S,Mizuki Y,Suzuki T,Katsura H,Yamada H,Endo Y,Osaki T,Ishizuka M,Tanaka T,Yamanaka N,Kurahashi T,Uto Y

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND/AIM:Detection of circulating tumor cells in the perioperative period predicts poor prognosis in patients with colorectal cancer. There is only one Food and Drug Administration-approved method for such detection, CellSearch, for which results have been inconsistent. A new immunological method, CytoTrack, has ...

journal_title：Anticancer research

authors： Gogenur M,Hillig T,Gogenur I

更新日期：2017-06-01 00:00:00

abstract：:Over 80% of clinically manifested prostate cancers respond to androgen withdrawal. Several alternatives to castration have been explored. Since a growth promoting role for androstenedione has been suggested, we investigated the effect of inhibition of 3 beta-hydroxy-steroid-dehydrogenase (3 beta-HSD), a key enzyme inv...

journal_title：Anticancer research

authors： Geldof AA,Dijkstra I,Newling DW,Rao BR

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:The tyrosine kinase inhibitors (TKI) sunitinib and imatinib were shown to induce macrocytosis in patients with renal cell cancer (RCC) and gastrointestinal stromal tumors (GIST), presumably through inhibition of the c-KIT dependent signaling pathway of erythroid progenitor cells of the bone marrow. PATIENTS...

journal_title：Anticancer research

authors： Schallier D,Trullemans F,Fontaine C,Decoster L,De Greve J

更新日期：2009-12-01 00:00:00

abstract：:The most widely-known anti-tumor drugs often induce marked immunosuppression which can give rise to one or more sepses. Anti-infection measures immediately applied can sometimes prove largely ineffective or even useless, the patient dying not as a result of the spread of the tumour but as a direct consequence of oppor...

journal_title：Anticancer research

authors： Castelli M,Baggio G,Ruberto AI,Malagoli M,Casolari C,Rossi T,Galatulas I

更新日期：1997-11-01 00:00:00

abstract：:Various new aminosterols were synthesized. The antiproliferative activity of these compounds (I-IV) was studied in vitro on a continuous human non small-cell bronchopulmonary carcinoma line (NSCLC-N6) at the cell cycle level. The histograms indicate cell blockage in Phase Gl (compound I-III) associated with a reductio...

journal_title：Anticancer research

authors： el Kihel L,Bosch S,Dherbomez M,Roussakis C,Letourneux Y

更新日期：1999-03-01 00:00:00

abstract：:Although several chemical carcinogenes have been shown to induce malignant transformation in human cells in culture, the molecular events involved in conversion of normal cells to malignant cells remain unknown at present. Normal human cells seem to be resistant to transformation by a single oncogene unless these cell...

journal_title：Anticancer research

authors： Khoobyarian N,Marczynska B

更新日期：1989-09-01 00:00:00

abstract：UNLABELLED:The diagnostic accuracy of fused positron emission tomography/computed tomography (PET/CT) was compared with CT alone and PET alone in the staging and re-staging of nasopharyngeal carcinoma (NPC) patients. PATIENTS AND METHODS:Eighty-six fluorine-18-2-fluoro-2-deoxy-D-glucose (FDG) PET/CT studies were retro...

journal_title：Anticancer research

authors： Chen YK,Su CT,Ding HJ,Chi KH,Liang JA,Shen YY,Chen LK,Yeh CL,Liao AC,Kao CH

更新日期：2006-03-01 00:00:00

abstract：:The cyanoguanidine CHS 828 was recently shown to possess potent anti-tumour effects both in vitro and in vivo. The exact mechanism of action of CHS 828 is not known, but recent results have indicated that induction of programmed cell death may be one mechanism by which CHS 828 exerts its anti-tumour effects. To invest...

journal_title：Anticancer research

authors： Hansen CM,Hansen D,Holm PK,Larsson R,Binderup L

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Long non-coding RNA differentiation antagonizing non-protein coding RNA (DANCR) is considered to be an oncogene in many cancer types. However, the role of DANCR in diagnosis and progression of hepatocellular carcinoma (HCC) is still unknown. PATIENTS AND METHODS:In this study, 146 participants including hea...

journal_title：Anticancer research

authors： Ma X,Wang X,Yang C,Wang Z,Han B,Wu L,Zhuang L

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate whether tributyrin, a natural butyrate pro-drug, as well as butyrate itself could affect growth, differentiation and apoptosis in two human pancreatic cancer cell lines in culture. MATERIALS AND METHODS:Proliferation was studied by cell counting using crystal violet ...

journal_title：Anticancer research

authors： Gaschott T,Maassen CU,Stein J

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND/AIM:Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel clinical approach to the treatment of peritoneal carcinomatosis. A well-established, not anatomic ex vivo PIPAC model was used to investigate the influence of changes in internal pressure, distance of the Micropump(©) (MIP) to the distri...

journal_title：Anticancer research

authors： Khosrawipour V,Khosrawipour T,Falkenstein TA,Diaz-Carballo D,Förster E,Osma A,Adamietz IA,Zieren J,Fakhrian K

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND/AIM:To describe real clinical outcomes when using systemic therapy to treat non-small cell lung cancer (NSCLC) patients who have anaplastic lymphoma kinase (ALK) fusion gene mutation. PATIENTS AND METHODS:We performed a retrospective chart review from April 2008 to March 2019 sourced from 16 medical institu...

journal_title：Anticancer research

authors： Okauchi S,Numata T,Nawa T,Ichimura H,Saito T,Hayashihara K,Yamada H,Satoh H,Endo T,Inage Y,Kaburagi T,Kiyoshima M,Yamada Y,Tamura T,Saito K,Inagaki M,Hizawa N,Sato Y,Shiozawa T,Sekine I,Ishikawa H,Kurihima K,S

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND/AIM:Despite recent introduction of several novel agents, limited data exist regarding parameters that help predict the progression of non-metastatic castration-resistant prostate cancer (nmCRPC). The objective of this study was to identify prognostic predictors in nmCRPC patients. PATIENTS AND METHODS:This ...

journal_title：Anticancer research

authors： Miyake H,Watanabe K,Matsushita Y,Watanabe H,Tamura K,Motoyama D,Ito T,Sugiyama T,Otsuka A

更新日期：2020-02-01 00:00:00

abstract：:To investigate the specific transduction of a suicide gene into human small cell lung carcinoma (SCLC) cells, we explored the promoter region of the neuron specific enolase (NSE) gene as a tumor-specific promoter. In Northern blot analysis, NSE mRNA was expressed more abundantly in the SBC3 human SCLC cell line than i...

journal_title：Anticancer research

authors： Tanaka M,Inase N,Miyake S,Yoshizawa Y

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Recently, 14-member macrolide antibiotics such as Clarithromycin and Roxithromycin (RXM) have been shown to have anti-cancer and anti-angiogeneic effects. However, it is not fully understood whether and how RXM suppresses angiogenesis in human hepatoma, which is a well-known hypervascular tumor. MATERIALS A...

journal_title：Anticancer research

authors： Aoki D,Ueno S,Kubo F,Oyama T,Sakuta T,Matsushita K,Maruyama I,Aikou T

更新日期：2005-01-01 00:00:00