Renin-angiotensin system blockade is not associated with hyperkalemia in chronic hemodialysis patients.

Abstract:

BACKGROUND:Serious hyperkalemia was reported in 10% of chronic hemodialysis (HD) patients that could lead to arrhythmia and death. Angiotensin-converting enzyme inhibitors (ACE-I) and angiotensin II receptor blockers (ARB) are well accepted for cardio-protective benefits. The relationship between renin-angiotensin system blockade (RASB) and hyperkalemia in chronic HD patients remains controversial. The aim of this study was to find the relationship between RASB and hyperkalemia in these patients. METHODS:Pre-dialysis serum potassium, clinical factors, and drugs were evaluated in 200 chronic HD patients in one HD center. Hyperkalemia was defined as serum K >or= 5.3 meq/L. Finally, multivariate analysis with logistic regression was used to evaluate the risk of hyperkalemia by RASB and other factors. RESULTS:In 200 patients, the mean K was 4.93 +/- 0.79 meq/L, and 70 (35%) patients had hyperkalemia. Fifty-eight (29%) patients were prescribed with RASB. Seven variables--non-DM, longer HD duration, lower dialysate calcium, lower serum glucose, higher serum iPTH, not using RASB, and not using furosemide--were more frequent in hyperkalemia group. In logistic regression analysis, RASB was associated with decreased odds for hyperkalemia (OR 0.262, p = 0.001 in model A; OR 0.205, p = 0.001 in model B). In addition, furosemide was associated with decreased odds for hyperkalemia (OR 0.068, p = 0.022 in model B). CONCLUSIONS:RASB is not associated with hyperkalemia in chronic HD patients.

journal_name

Ren Fail

journal_title

Renal failure

authors

Lin HH,Yang YF,Chang JK,Ting IW,Kuo HL,Wang IK,Huang CC

doi

10.3109/08860220903216147

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

942-5

issue

10

eissn

0886-022X

issn

1525-6049

journal_volume

31

pub_type

杂志文章
  • Outcomes and APACHE II predictions for critically ill patients with acute renal failure requiring dialysis.

    abstract:BACKGROUND:Despite the widespread availability of dialytic and intensive care unit technology, the probability of early mortality in critically ill patients with acute renal failure (ARF) is still high, and the evaluation of the patients' prognosis has been difficult. The Acute Physiology and Chronic Health Evaluation ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1081/jdi-100001284

    authors: Chen YC,Hsu HH,Kao KC,Fang JT,Huang CC

    更新日期:2001-01-01 00:00:00

  • A Behçet case with renal amyloidosis.

    abstract::Behçet's disease is a chronic systemic vasculitis with unknown etiology characterized by recurrent oral and genital ulcerations, ocular inflammation,having manifestations related to the skin and joints. Neurologic, pulmonary and gastrointestinal findings can also be observed during the course of the disease. In this r...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1081/jdi-120018734

    authors: Nadir I,Gültekin F,Yönem O,Yildiz E

    更新日期:2003-03-01 00:00:00

  • Tacrolimus restores podocyte injury and stabilizes the expression of Cabin1 in 5/6 nephrectomized rats.

    abstract::Podocyte injury is a vital factor, which induces massive proteinuria. Studies have shown that tacrolimus (TAC) protected podocyte via stabilizing cytoskeleton. Our latest study indicates that calcineurin binding protein 1 (Cabin1) undergoes nuclear translocation during podocytes injury. Whether TAC targets on Cabin1 d...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2016.1148936

    authors: Wen Y,Liu L,Zhou P,Li H,Wang Z,Zhang Y,Liang J

    更新日期:2016-01-01 00:00:00

  • Role of ticlopidine on adriamycin-induced nephropathy.

    abstract::The effect of ticlopidine on rats with adriamycin nephropathy was observed during 26 weeks. In the ticlopidine-treated nephrotic animals (TNG), proteinuria was less than in the untreated nephrotic animals (NG), but this difference was significant only at week 6 (TNG = 47.27 +/- 16.52 versus NG = 100.08 +/- 13.83 mg/24...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229909045185

    authors: Riyuzo MC,Soares VA

    更新日期:1999-09-01 00:00:00

  • Renal stone disease and obesity: what is important for urologists and nephrologists?

    abstract::Currently, obesity has reached an epidemic stage and represents a challenge for health authorities across the globe. Certainly, with emergence of obesity epidemic, we started to see an increase in the prevalence of chronic kidney disease (CKD) and nephrolithiasis. Interestingly, epidemiologic studies have shown that t...

    journal_title:Renal failure

    pub_type: 杂志文章,评审

    doi:10.3109/0886022X.2012.723777

    authors: Ahmed MH,Ahmed HT,Khalil AA

    更新日期:2012-01-01 00:00:00

  • Renal cortical necrosis is a disappearing entity in obstetric acute kidney injury in developing countries: our three decade of experience from India.

    abstract:RATIONAL:Obstetrical complications are the commonest causes of Renal Cortical Necrosis (RCN). However, the overall incidence of RCN in obstetric acute kidney injury in developing countries has been decreasing in recent years. OBJECTIVE:The aim of this study was to evaluate the changing profile of RCN in obstetric AKI ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2015.1062340

    authors: Prakash J,Pant P,Singh AK,Sriniwas S,Singh VP,Singh U

    更新日期:2015-08-01 00:00:00

  • Parathyroid hormone levels, calcium-channel blockers, and the dyslipidemia of nondiabetic hemodialysis patients.

    abstract:BACKGROUND:Experimental studies have shown that increased levels of parathyroid hormone (PTH) in uremia may cause elevation of intracellular calcium, predisposing to insulin resistance and lipid metabolism abnormalities. Administration of calcium-channel blockers (CCBs) in these models protects against the development ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:

    authors: Zanos S,Mitsopoulos E,Sakellariou G

    更新日期:2005-01-01 00:00:00

  • Effects of uric acid-lowering therapy on the progression of chronic kidney disease: a systematic review and meta-analysis.

    abstract:OBJECTIVES:Whether uric acid levels were associated with the progression of chronic kidney disease (CKD) remained controversial. This meta-analysis was aimed to assess the effect of lowering serum uric acid therapy on the progression of CKD to clarify the role of uric acid in the progression of CKD indirectly. METHODS...

    journal_title:Renal failure

    pub_type: 杂志文章,meta分析,评审

    doi:10.1080/0886022X.2018.1456463

    authors: Liu X,Zhai T,Ma R,Luo C,Wang H,Liu L

    更新日期:2018-11-01 00:00:00

  • Effect of arachidonic acid metabolic inhibitors on hypoxia/reoxygenation-induced renal cell injury.

    abstract::The present study was undertaken to examine the role of arachidonic acid (AA) metabolites in hypoxia/reoxygenation (H/R)-induced renal cell injury in rabbit renal cortical slices using AA metabolic inhibitors. Inhibitors of cyclooxygenase (indomethacin and diclofenac sodium) and lipoxygenase pathways (nordihydroguaiar...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1081/jdi-100100860

    authors: Kim YK,Hwang MY,Woo JS,Jung JS,Lee SH

    更新日期:2000-03-01 00:00:00

  • Association between VEGF receptors and baseline peritoneal transport status in new peritoneal dialysis patients.

    abstract:BACKGROUND:Peritoneal transport status is important not only for prescription, but also as a prognostic index. Flt-1 and Flk-1, the major vascular endothelial growth factor receptors involved in angiogenesis and hyperpermeability, may play a potent role in determining peritoneal transport characteristics. However, the ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2012.669322

    authors: Zhang AH,Wang G,Zhang DL,Zhang QD,Liu S,Liao Y,Yin Y,Liu WH

    更新日期:2012-01-01 00:00:00

  • Fasudil ameliorates rhabdomyolysis-induced acute kidney injury via inhibition of apoptosis.

    abstract::During times of war or natural disasters, rhabdomyolysis leading to acute kidney injury (AKI) can assume epidemic proportions. Fasudil attenuates ischemia/reperfusion-induced AKI. We investigated the therapeutic effect of an early application of fasudil on AKI induced by rhabdomyolysis and explored the potential mecha...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.601830

    authors: Wang YD,Zhang L,Cai GY,Zhang XG,Lv Y,Hong Q,Shi SZ,Yin Z,Liu XF,Chen XM

    更新日期:2011-01-01 00:00:00

  • Early detection of acute tubular injury with diffusion-weighted magnetic resonance imaging in a rat model of myohemoglobinuric acute renal failure.

    abstract::We evaluated the feasibility of magnetic resonance imaging (MRI) for early detection of tubular injury by monitoring changes in the apparent diffusion coefficient (ADC) of renal water in a rat model of myohemoglobinuric glycerol-induced acute renal failure (ARF). Diffusion-weighted MRI was performed concurrently with ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229609052773

    authors: Vexler VS,Roberts TP,Rosenau W

    更新日期:1996-01-01 00:00:00

  • Lupus nephritis at the University Hospital of the West Indies, Kingston, Jamaica: a 10-year experience.

    abstract::The case records of 75 patients who had systemic lupus erythematosus (SLE) and renal involvement on renal histology were reviewed. There were 70 females and 5 males, with a ratio of 14:1. The majority of the patients were in their second and third decades of life. SLE nephritis was distinctly uncommon in patients belo...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229009066962

    authors: Williams W,Shah D

    更新日期:1990-01-01 00:00:00

  • Apelin and nutritional status in children on dialysis.

    abstract:BACKGROUND:We aimed to evaluate whether serum apelin could reflect the nutritional status of children on dialysis. METHODS:Twelve patients on peritoneal dialysis (PD) and 20 patients on hemodialysis (HD) were enrolled. Patients received individualized diet for six months. Anthropometric and laboratory indices were mea...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2014.937661

    authors: Yavuz S,Cetinkaya S,Anarat A,Bayazıt AK

    更新日期:2014-09-01 00:00:00

  • Renal cortical mitochondria are the source of oxygen free radicals enhanced by gentamicin.

    abstract::Rat renal cortical mitochondria were isolated from Wistar male rats weighing 80 to 120 g to investigate whether the source of oxygen free radicals was renal cortical mitochondria enhanced by gentamicin. In renal cortical mitochondria with or without the addition of gentamicin, DMSO, DFO, CAT, SOD, and MT1 were added s...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229509036371

    authors: Yang CL,Du XH,Han YX

    更新日期:1995-01-01 00:00:00

  • Development of hypertension in a pyelonephritis-induced model: the effect of salt intake and inability of renal sodium handling.

    abstract::The role of the kidney in the control of blood pressure has been convincingly demonstrated by several studies. Recent evidence has suggested that subtle acquired tubulointerstitial injury may cause a defect in sodium excretion function, thus leading to salt-sensitive hypertension. There are no reports, however, examin...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220600779058

    authors: de Magalhães Sartim R,Fantinato Menegon L,de Almeida AR,Rocha Gontijo JA,Aline Boer P

    更新日期:2006-01-01 00:00:00

  • The course of hypercalciuria and related markers of bone metabolism parameters associated with corticosteroid treatment.

    abstract:BACKGROUND AND OBJECTIVE:Prolonged corticosteroid (CS) use induces osteoporosis; the pathogenesis of this condition is multifactorial and includes CS-induced hypercalciuria. We investigated the course of hypercalciuria and related markers of bone metabolism parameters during and after the CS treatment. MATERIALS AND M...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2011.648596

    authors: Duzen O,Erkoc R,Begenik H,Soyoral YU,Aldemir MN

    更新日期:2012-01-01 00:00:00

  • Low employment and low willingness of being reemployed in Chinese working-age maintained hemodialysis patients.

    abstract:AIM:Returning to society plays an important role in improving the quality of life in maintenance hemodialysis (MHD) patients, and retention of employment is one of the core enablers. The study is to assess the employment status and to determine the variables for unemployment in Chinese MHD patients. METHODS:Prevalent ...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/0886022X.2017.1361834

    authors: Huang B,Lai B,Xu L,Wang Y,Cao Y,Yan P,Chen J

    更新日期:2017-11-01 00:00:00

  • Effects of regular exercise on anxiety, depression, and quality of life in maintenance hemodialysis patients.

    abstract:BACKGROUND:Psychological problems such as depression and anxiety are common in hemodialysis patients. In several studies, exercise programs were effective in relieving depression or anxiety in these patients, although not all agree. PURPOSE:In this study, we evaluated the effects of an exercise program on exercise cap...

    journal_title:Renal failure

    pub_type: 临床试验,杂志文章

    doi:10.1081/jdi-120005367

    authors: Suh MR,Jung HH,Kim SB,Park JS,Yang WS

    更新日期:2002-05-01 00:00:00

  • Discrimination between postinfectious IgA-dominant glomerulonephritis and idiopathic IgA nephropathy.

    abstract:BACKGROUND:A unique form of postinfectious glomerulonephritis (PIGN) with IgA-dominant deposition mimicking IgA nephropathy has been increasingly reported. METHODS:We compared the clinical and histological features of 12 patients with postinfectious IgA-dominant glomerulonephritis to 134 patients with idiopathic IgA n...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860221003753331

    authors: Wen YK,Chen ML

    更新日期:2010-06-01 00:00:00

  • Atrial natriuretic peptide as a preload depressor in acute renal failure secondary to congestive heart failure.

    abstract::The present study was undertaken to verify the hypothesis that infusion of atrial natriuretic peptide (ANP) might lower preload and be beneficial in the treatment of pulmonary congestion even without a diuresis in patients with acute renal failure (ARF) secondary to severe congestive heart failure (CHF). We studied 22...

    journal_title:Renal failure

    pub_type: 临床试验,杂志文章

    doi:10.3109/08860229809045168

    authors: Seta K,Hayashi T,Sugawara A,Kasuno K,Watanabe S,Sumi Y,Kijima Y,Kawaguchi K,Kotake C,Seo T,Toda T,Kuwahara T

    更新日期:1998-09-01 00:00:00

  • A prospective study of thromboelastography (TEG) and filter life during continuous veno-venous hemofiltration.

    abstract::Anticoagulants are commonly used to prolong circuit life during continuous hemofiltration. However, a clear correlation between routinely performed blood coagulability tests and circuit life has not been demonstrated. This lack of correlation may derive from the limited ability of such tests to describe the likelihood...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1081/jdi-100100873

    authors: Baldwin I,Tan HK,Bridge N,Bellomo R

    更新日期:2000-05-01 00:00:00

  • Furosemide prevents apoptosis and associated gene expression in a rat model of surgical ischemic acute renal failure.

    abstract::Recently, we demonstrated that furosemide improves renal hemodynamics and attenuates ischemia/reperfusion (I/R)-associated changes in angiogenesis-related gene expression. However, the effect of furosemide on I/R-induced apoptosis is not known. We utilized a rat model of acute ischemic nephropathy to test the hypothes...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220701263671

    authors: Aravindan N,Aravindan S,Riedel BJ,Weng HR,Shaw AD

    更新日期:2007-01-01 00:00:00

  • Long-term online hemodiafiltration does not reduce the frequency and severity of acquired cystic kidney disease in hemodialysis patients.

    abstract:BACKGROUND:Acquired cystic kidney disease (ACKD) is a frequent complication in chronic hemodialysis (HD) patients and a risk factor for renal cell carcinoma. Online hemodiafiltration (HDF) provides better clearance of middle molecular weight solutes, but its effect on ACKD has not been investigated. MATERIALS AND METH...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220903003412

    authors: Weng CJ,Chang MY,Chen YC,Tian YC,Fang JT,Yang CW

    更新日期:2009-01-01 00:00:00

  • Efficacy of leflunomide combined with prednisone in the treatment of refractory nephrotic syndrome.

    abstract:OBJECTIVE:To assess the safety and clinical efficacy of leflunomide (LEF) and prednisone on refractory nephrotic syndrome (RNS). METHODS:A total of 52 patients with RNS were treated for 24 weeks between 2010 and 2014 in our hospital. In the treated group, 26 patients were treated with LEF and prednisone, and, in the c...

    journal_title:Renal failure

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/0886022X.2016.1172917

    authors: Liu Y,Qu X,Chen W,Zhang Y,Liu L

    更新日期:2016-11-01 00:00:00

  • Antioxidant U74389G improves glycerol-induced acute renal failure without affecting PPARgamma gene.

    abstract::Oxygen metabolites play an important role in the pathogenesis of myoglobinuric acute renal failure (ARF). Previously, we have reported a down regulation of peroxisome proliferator activated receptor gamma (PPARgamma) in glycerol-induced ARF, and the induction of PPARgamma has been shown to provide renal protection. In...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220701573483

    authors: Yousefipour Z,Hercule H,Oyekan AO,Newaz MA

    更新日期:2007-01-01 00:00:00

  • Acute cyclosporin A renal dysfunction in dogs reversed by calcium antagonists and antiplatelet agents.

    abstract::The aim of this study was to assess the effect of nifedipine and piracetam alone or in combination in the protection of renal function and morphology after cyclosporin A (CyA) administration. Thirty healthy mongrel dogs with a mean body weight of 15 kg were sacrificed. Six animals (group C) were given CyA 20 mg/kg bod...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860229209047658

    authors: Grekas D,Alivanis P,Kalekou H,Papayianni K,Karamouzis M,Tourkantonis A

    更新日期:1992-01-01 00:00:00

  • Monitor lizard bite-induced acute kidney injury--a case report.

    abstract::Envenomations by venomous lizards are rare. Monitor lizard bite-induced acute kidney injury (AKI) is a previously unreported complication in humans. A 55-year-old female was bitten on her right leg during farming activity by a monitor lizard (Varanus bengalensis). The patient experienced severe local pain and bleeding...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/0886022X.2013.868223

    authors: Vikrant S,Verma BS

    更新日期:2014-04-01 00:00:00

  • Assessment of hemodialysis adequacy by ionic dialysance: comparison to standard method of urea removal.

    abstract:BACKGROUND:The hemodialysis adequacy is one of the most important issues influencing the survival of patients on maintenance hemodialysis (HD). Assessment of measuring the delivered dialysis dose using clearance x time/volume (Kt/V) index requires multiple blood sampling. New methods for assessment of dialysis dose bas...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.1080/08860220500200262

    authors: Racki S,Zaputović L,Maleta I,Grzetić M,Mavrić Z,Devcić B,Vujicić B

    更新日期:2005-01-01 00:00:00

  • Familial Mediterranean fever and membranous glomerulonephritis: report of a case.

    abstract::Familial Mediterranean fever (FMF) is an autosomal recessive genetic disease characterized by recurrent attacks of fever and painful episodes of sterile polyserositis. Kidney involvement may occur as a result of secondary amyloidosis during the course of FMF. Previously, different types of glomerulopathies such as IgM...

    journal_title:Renal failure

    pub_type: 杂志文章

    doi:10.3109/08860221003640090

    authors: Ceri M,Unverdi S,Altay M,Unverdi H,Ensari A,Duranay M

    更新日期:2010-01-01 00:00:00