Abstract：
BACKGROUND:This study was conducted to evaluate the effect of levonorgestrel-releasing intrauterine devices (LNG-IUDs) on menorrhagia in patients receiving anticoagulant therapy after cardiac valve replacement. STUDY DESIGN:Forty women with menorrhagia who underwent cardiac valve replacement and were taking anticoagulant medication were enrolled in the study. The women were randomly divided into two groups: LNG-IUDs were inserted into 20 women in Group 1 over the first 3 days of menstrual bleeding, while the women in Group 2 were followed without any intervention. The activated partial thromboplastin time, prothrombin time, international normalized ratio, hematocrit level, hemoglobin level, ferritin level and pictorial bleeding assessments for the quantity of menstrual bleeding were recorded. RESULTS:Three months after insertion of LNG-IUDs, the women in Group 1 had a significant decrease in blood loss and higher hemoglobin, hematocrit and ferritin values. No difference was detected for these parameters in the control group at the third and sixth months of the study. Coagulation parameters did not differ between the two groups. CONCLUSION:LNG-IUDs can be considered as an effective non-surgical treatment for menorrhagia in women receiving anticoagulant therapy after cardiac valve replacement.
journal_name
Contraceptionjournal_title
Contraceptionauthors
Kilic S,Yuksel B,Doganay M,Bardakci H,Akinsu F,Uzunlar O,Mollamahutoglu Ldoi
10.1016/j.contraception.2009.02.007subject
Has Abstractpub_date
2009-08-01 00:00:00pages
152-7issue
2eissn
0010-7824issn
1879-0518pii
S0010-7824(09)00047-Xjournal_volume
80pub_type
杂志文章,随机对照试验相关文献
CONTRACEPTION文献大全abstract：:As research has shown that knowledge concerning the health risks and benefits of oral contraceptive (OC) use is a contributor to OC compliance, the following study examined an educated sample of young women to determine the level of knowledge concerning the risks and benefits of OC use. A 28-item questionnaire was dev...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/s0010-7824(01)00194-9
更新日期：2001-04-01 00:00:00
abstract：OBJECTIVE:I examine Twitter discussion regarding the Texas omnibus abortion restriction bill before, during and after Wendy Davis' filibuster in summer 2013. This critical moment precipitated wide public discussion of abortion. Digital records allow me to characterize the spatial distribution of participants in Texas a...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2014.07.007
更新日期：2014-11-01 00:00:00
abstract：:The advantages of delivering drugs through the skin for systemic therapy have been widely recognized and represent a growing sector in drug development. Transdermal delivery of steroids is also a rapidly expanding field and in various clinical situations where hormonal replacement therapy is needed this route of admin...
journal_title：Contraception
pub_type： 杂志文章,评审
doi：10.1016/0010-7824(89)90012-7
更新日期：1989-01-01 00:00:00
abstract：:Mechanisms for the therapeutic effect of oral contraceptives in dysmenorrhea were studied by recording intrauterine pressure on the first day of menstrual bleeding in women with moderate to severe symptoms and after three weeks of oral contraceptive therapy (150 micrograms levonorgestrel + 30 micrograms ethinyl estrad...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(89)90026-7
更新日期：1989-07-01 00:00:00
abstract：:A 10% sample of the data from East China from the two-per-thousand fertility and contraception survey of the Chinese State Family Planning Committee was analysed to study determinants of contraceptive choice in three situations: after first surviving delivery; before first abortion after first surviving delivery; and ...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(93)90022-y
更新日期：1993-06-01 00:00:00
abstract：OBJECTIVE:To demonstrate the feasibility and safety of training midlevel healthcare providers (midwives and family nurses) to provide medical abortion and postabortion contraception in underserved areas in Kyrgyzstan. STUDY DESIGN:This was an implementation study at four referral facilities and 28 Felsher Obstetric Po...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2017.11.002
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVE:This pilot study investigates whether an educational handout could increase short-term information retention about drug interactions between antiepileptic drugs (AEDs) and hormonal contraceptives among female epilepsy patients of reproductive age. STUDY DESIGN:This is a pilot randomized controlled trial of a...
journal_title：Contraception
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.contraception.2015.07.008
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Provision of contraception is often linked with physical examination, including clinical breast examination (CBE) and pelvic examination. This review was conducted to evaluate the evidence regarding outcomes among women with and without physical examination prior to initiating hormonal contraceptives. STUDY...
journal_title：Contraception
pub_type： 杂志文章,评审
doi：10.1016/j.contraception.2012.08.010
更新日期：2013-05-01 00:00:00
abstract：:This study was undertaken to assess the effects of different tubal occlusion procedures on ovarian function. Three groups of subjects randomized to tubal occlusion by laparoscopy and Yoon ring (24 subjects), minilaparotomy and Yoon ring (19 subjects) and minilaparotomy and Pomeroy (22 subjects), and one separate contr...
journal_title：Contraception
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0010-7824(89)90003-6
更新日期：1989-08-01 00:00:00
abstract：:In 1991, the source of public sector condom supplies in an African country changed from USAID to WHO. Following a complaint, the two types of condoms were sampled and compared. Laboratory tests indicated that the new-style condoms were of adequate quality, but a number of differences were noted between the two types. ...
journal_title：Contraception
pub_type： 杂志文章,评审
doi：10.1016/0010-7824(95)00183-b
更新日期：1995-10-01 00:00:00
abstract：OBJECTIVES:To compare the pharmacokinetic parameters and safety of the progestagen, Org 30659, (17alpha)-17-hydroxy-11-methylene-19-norpregna-4,15-dien-20-yn-3-one), and ethinyl estradiol (EE) in Caucasian and Japanese women after single and multiple doses. METHODS:This was an open-label parallel design of a single do...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/s0010-7824(03)00140-9
更新日期：2003-09-01 00:00:00
abstract：:A chemically deglycosylated derivative of ovine luteinizing hormone (LH) exhibited appreciable binding to the receptor but had minimal steroidogenic activity. In immature female rats primed with pregnant mare serum gonadotropin, the deglycosylated LH showed low ovulation-inducing activity. Ovulation induced by ovine L...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(80)90037-2
更新日期：1980-06-01 00:00:00
abstract：:Eighty-four Chinese patients attending the Family Planning Association of Hong Kong for contraception with oral contraceptive pills were randomized into 2 groups. The first group received pills containing 0.15 mg levonorgestrel and 0.03 mg ethinyl oestradiol. The second group received pills containing 0.15 mg desogest...
journal_title：Contraception
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0010-7824(90)90126-g
更新日期：1990-01-01 00:00:00
abstract：:Primary cultures of rat Leydig and Sertoli cells were used to evaluate the direct effects of GTW on testicular cells and to compare these to the effects of gossypol acetate. Both GTW and gossypol acetate can affect the survival of Leydig and Sertoli cells. But Sertoli cells are much more sensitive than Leydig cells, e...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(92)90069-6
更新日期：1992-03-01 00:00:00
abstract：OBJECTIVE:Limitations on didactic time pose barriers to teaching non-directive pregnancy options counseling. This study set out to explore the use of an online module to support trainee performance in a pregnancy options counseling standardized-patient exercise implemented among third-year medical students, and to exam...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2016.03.005
更新日期：2016-10-01 00:00:00
abstract：:The effect of aromatase inhibitors on the implantation process is not well known. This study examined the anti-implantation action in rats of a nonsteroidal aromatase inhibitor of high specific activity, fadrozole hydrochloride (Fad). Continuous subcutaneous infusion of Fad at 300 microg/day from Day 1 (the day of spe...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/s0010-7824(03)00076-3
更新日期：2003-07-01 00:00:00
abstract：:Research has established the principle of hormonal male contraception based on suppression of gonadotropins and spermatogenesis. All hormonal male contraceptives use testosterone, but only in East Asian men can testosterone alone suppress spermatogenesis to a level compatible with contraceptive protection. In Caucasia...
journal_title：Contraception
pub_type： 杂志文章,评审
doi：10.1016/j.contraception.2010.03.020
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND:Incarcerated women have had limited access to health care prior to their arrest. Although their incarceration presents an opportunity to provide them with health care, their reproductive health needs have been overlooked. STUDY DESIGN:We performed a cross-sectional study of a nationally representative sampl...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2009.05.126
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVES:Federally Qualified Health Centers (FQHCs) are a major and growing source of primary care for low-income women of reproductive age; however, only limited knowledge exists on the scope of family planning care they provide and the mechanisms for delivery of these essential reproductive health services, includi...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2013.09.015
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVE:To determine the acceptability of taking mifepristone at home for early medical abortion in the United States. STUDY DESIGN:This prospective, non-randomized, open-label study at six Planned Parenthood centers gave women with pregnancies up to 63 days' gestation seeking medical abortion the choice of taking m...
journal_title：Contraception
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.contraception.2015.06.026
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVE:This study was aimed to evaluate a marketed mineralo-herbal preparation containing plants known to have potent contraceptive activity, or contraindicated for use during pregnancy in folklore/ancient Indian literature and recommended for use as an appetizer and headache, hyperacidity and chronic constipation r...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2005.05.026
更新日期：2005-12-01 00:00:00
abstract：:This review provides an update of previous estimates of first-year probabilities of contraceptive failure for all methods of contraception available in the United States. Estimates are provided of probabilities of failure during typical use (which includes both incorrect and inconsistent use) and during perfect use (c...
journal_title：Contraception
pub_type： 杂志文章,评审
doi：10.1016/j.contraception.2011.01.021
更新日期：2011-05-01 00:00:00
abstract：:A structured literature review was undertaken to determine, in the context of early medical abortion, the proportion of women who require analgesia, the predictors of analgesia requirement and the most appropriate analgesia regimen. Studies from different centers show wide variations in analgesia use, but, overall, ar...
journal_title：Contraception
pub_type： 杂志文章,评审
doi：10.1016/j.contraception.2006.03.002
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND:In levonorgestrel intrauterine system (LNG-IUS) users, the prevention of sperm penetration through cervical mucus has not been demonstrated. STUDY DESIGN:Subjects were enrolled in an investigator-blinded study to compare quality and sperm penetrability of mid-cycle cervical mucus between LNG-IUS users and h...
journal_title：Contraception
pub_type： 临床试验,杂志文章
doi：10.1016/j.contraception.2010.06.006
更新日期：2010-12-01 00:00:00
abstract：:The morphology and the related composition of T-type intrauterine devices (IUDs) made of gold-plated copper were studied in relation to patient complaints. The removed IUDs were examined without pretreatment by scanning electron microscopy and energy dispersive x-ray spectroscopy. Besides the previously found incrusta...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2004.03.006
更新日期：2004-08-01 00:00:00
abstract：:Fructose levels and fructolysis index in human semen were analysed to assess a correlation, if any, between the levels of this glycolysable sugar and sperm concentration. Semen was collected from normospermic men and men with azoospermia or oligospermia. Seminal fructose levels were elevated in men with obstructive az...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(89)90062-0
更新日期：1989-03-01 00:00:00
abstract：OBJECTIVE:To determine the pharmacokinetics (PK) of drospirenone (DRSP), alone versus in combination with ethinyl estradiol (EE), after single and repeated administration. STUDY DESIGN:We conducted a single-centre, open-label, crossover, 2-treatment, 2-period, 2-sequence study in which non-micronized DRSP 4 mg or a co...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2019.10.005
更新日期：2020-02-01 00:00:00
abstract：:The ability of 40 mg of milled suspension of a new long-acting androgen ester (20 Aet-1) to restore and maintain accessory gland function was compared with that of testosterone enanthate (TE) in castrated adult rhesus monkeys. Castration did not abolish the ejaculatory response since only two animals did not void seme...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(91)90129-4
更新日期：1991-01-01 00:00:00
abstract：:This was a double-blind randomized control study to evaluate the efficacy of cervical priming by nitric oxide donor before second-trimester induced abortion. One-hundred healthy women with a singleton pregnancy between 14 and 20 weeks of gestation were randomized into either 40 mg isosorbide mononitrate or placebo, gi...
journal_title：Contraception
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0010-7824(03)00170-7
更新日期：2003-10-01 00:00:00
abstract：:This investigation describes the synthesis of a biodegradable hydrogel composed of a core surrounded by four concentric sheaths containing dextran, copolymers of polylactide and epsilon-caprolactone. The hydrogel was impregnated with iron (II) d-gluconate dihydrate, which causes complete spermiostasis due to lipid per...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2004.02.015
更新日期：2004-09-01 00:00:00
