Performing bone marrow aspiration and biopsy in children: Recommended guidelines.

Abstract:

:Bone marrow aspiration (BMA) and bone marrow trephine biopsy are important procedures for the diagnosis of hematological malignancies and nonmalignant diseases in children. During BMA, bone marrow particles are obtained for analysis including microscopic morphologic evaluations and differential counts. During a trephine biopsy, a core of bone marrow is obtained and processed for the evaluation of marrow cellularity and to rule out marrow involvement by solid tumours, lymphomas or other processes. These invasive procedures should only be performed by a trained individual following a standard operating technique. There are no clear published guidelines in the paediatric literature. Hence, the purpose of the present article is to provide guidelines for the performance of BMAs and bone marrow trephine biopsies in children that will be useful for both general paediatricians and paediatric hematologists and oncologists.

journal_name

Paediatr Child Health

authors

Abla O,Friedman J,Doyle J

doi

10.1093/pch/13.6.499

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

499-501

issue

6

eissn

1205-7088

issn

1918-1485

journal_volume

13

pub_type

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