Abstract：
OBJECTIVE:To identify a target group of children with acute immune thrombocytopenic purpura (ITP) that may not require hospitalization for management. METHODS:A retrospective chart review was conducted of all children admitted over a two-year period to a tertiary care paediatric hospital with the diagnosis of acute ITP. Patients were classified according to typical and atypical presentations. Typical patients were defined as those aged between one and 10 years, with no hepatomegaly or significant splenomegaly and who had typical laboratory features for ITP. Patients who did not meet these criteria were categorized as atypical. Outcome measures included length of stay (LOS) in hospital; frequency of bone marrow aspiration (BMA); type of treatment; incidence of intracranial hemorrhage (ICH) or severe bleeding; and admission and discharge platelet counts. RESULTS:There were 74 patients hospitalized for a mean of 3.6 days. No patients suffered an ICH or bleeding requiring transfusion. Patients with typical presentations (42) were compared with patients with atypical presentations (32) and were not significantly different for clinically important outcomes such as admission and discharge platelet counts, serious complications or type of therapy. Typical patients had significantly fewer BMAs than did atypical patients - 22 of 42 (52%) versus 25 of 32 (78%) (P=0.02), and a shorter LOS - 3.1 (+/-0.9) days versus 4.2 (+/-1.8) days (P=0.01). CONCLUSIONS:Children presenting with ITP have a low incidence of bleeding complications and many of these patients can be managed as outpatients. A multicentre study is needed to properly delineate a low risk group suited for outpatient medical management.
journal_name
Paediatr Child Healthjournal_title
Paediatrics & child healthauthors
Berman J,Young N,Carcao M,Blanchette V,Ipp Mdoi
10.1093/pch/7.6.386subject
Has Abstractpub_date
2002-07-01 00:00:00pages
386-9issue
6eissn
1205-7088issn
1918-1485journal_volume
7pub_type
杂志文章abstract：:In the past three decades, rapidly changing demographic characteristics have been witnessed in western society. Concurrently, numerous culture-related studies have attested to the disparity in health services among different ethnic groups. Reports have shown contributing factors that can render main stream services in...
journal_title：Paediatrics & child health
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journal_title：Paediatrics & child health
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journal_title：Paediatrics & child health
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journal_title：Paediatrics & child health
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journal_title：Paediatrics & child health
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journal_title：Paediatrics & child health
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更新日期：2004-05-01 00:00:00
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journal_title：Paediatrics & child health
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更新日期：1998-11-01 00:00:00
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更新日期：2018-04-01 00:00:00
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journal_title：Paediatrics & child health
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更新日期：2012-11-01 00:00:00
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更新日期：2020-08-01 00:00:00
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