Chemical composition and in vitro anti-inflammatory activity of apple phenolic extracts and of their sub-fractions.

Abstract:

:Apple extract powders from three different manufacturers were investigated for their anti-inflammatory activity, their total phenolic content, and their chemical composition. The samples represented two production batches for two products and a single batch of a third. The samples showed similar, but clearly different, anti-inflammatory activities, and had substantially different total phenolic contents, and different chemical compositions. Differences in chemical composition for batches of the same product were significant, although not as great as differences between products. The samples were fractionated into chemical classes. The most active fractions were those that contained epicatechin, catechin with phloridzin and quercetin glycosides, or those that contained procyanidin polymers. It was not possible to link activity to the presence of individual components or combinations of these. If fruit extracts are to be reliably linked to validated health benefits, then the source materials, the extraction processes, and the final composition of such products need to be more clearly defined than at present.

journal_name

Int J Food Sci Nutr

authors

Lauren DR,Smith WA,Adaim A,Cooney JM,Wibisono R,Jensen DJ,Zhang J,Skinner MA

doi

10.1080/09637480902849203

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

188-205

eissn

0963-7486

issn

1465-3478

pii

910664455

journal_volume

60 Suppl 7

pub_type

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