Smoking and oral contraceptive continuation.

Abstract:

BACKGROUND:Smoking may be related to early discontinuation of oral contraceptives (OC). STUDY DESIGN:This was a planned secondary analysis of a randomized clinical trial. Women aged less than 25 initiating OC at three inner-city publicly funded family planning clinics enrolled in the study. Subjects reported smoking status at enrollment; 3- and 6-month interviews assessed OC continuation. RESULTS:One hundred eighty-nine (12%) of 1598 participants were current smokers. Smokers were more often lost to follow-up than nonsmokers (P<.01). Among participants with a 6-month interview, only 26% of smokers and 46% of nonsmokers were continuing OC (P<.001). After adjustment for confounding factors, smokers were still somewhat less likely to be continuing OC (adjusted OR 0.6, 95% CI 0.4-1.0). This association was unrelated to number of cigarettes smoked per day. CONCLUSIONS:These data suggest that young smokers may be more likely to discontinue OC within 6 months than nonsmokers. Smoking may be a marker for risk-taking behavior that extends to the premature discontinuation of OC.

journal_name

Contraception

journal_title

Contraception

authors

Westhoff C,Jones K,Robilotto C,Heartwell S,Edwards S,Zieman M,Cushman L

doi

10.1016/j.contraception.2008.12.003

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

375-8

issue

5

eissn

0010-7824

issn

1879-0518

pii

S0010-7824(08)00552-0

journal_volume

79

pub_type

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