Chronic lymphocytic leukaemia.

abstract：BACKGROUND:Human neuroblastoma and medulloblastoma express abnormal ganglioside patterns especially GD2 and GM2 which are important for tumour growth. We tested the effects of L-cycloserine (L-CS), a potent inhibitor of synthesis of glycosphingolipids, on the growth, viability and expression of GD2 and GM2 in neuroblas...

journal_title：Anticancer research

authors： Cinatl J Jr,Cinatl J,Kotchetkov R,Pouckova P,Vogel JU,Rabenau H,Michaelis M,Kornhuber B

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND/AIM:To assess prognosis of women aged 75 and older according to breast cancer (BC) diagnosis circumstances. PATIENTS AND METHODS:A retrospective cohort study was conducted in the Amiens, France, regional oncologic referral center between 2005 and 2015. Two groups were formed depending on whether the patient...

journal_title：Anticancer research

authors： Ilenko A,Sergent F,Mercuzot A,Zitoun M,Chauffert B,Foulon A,Gondry J,Chevreau J

更新日期：2017-02-01 00:00:00

abstract：:Bright and dark field microscopy were used to examine interphase nuclei and RBG-banded human chromosomes. In dark field microscopy both chromosomes and interphase chromatin appeared to be composed of similar independent structures alternating between bright and dull light intensity. The position, colour, and number of...

journal_title：Anticancer research

authors： Rønne M,Gyldenholm AO,Storm CO

更新日期：1995-03-01 00:00:00

abstract：:A copper complex with superoxide dismutase mimetic activity, Cu(II)2 (3,5-diisopropylsalicylate)4 (CuDIPS), was tested for activity against mammary cancer in female C3H/HeNCR mice. Initiation of treatment at 20 or at 30 weeks of age had a limited beneficial effect on survival rates. Further, a small, but not statistic...

journal_title：Anticancer research

authors： Crispens CG Jr,Sorenson JR

更新日期：1992-07-01 00:00:00

abstract：:Megakaryocyte polyploidization is an advantageous and regulated mechanism which leads to an increase in platelet production. In megakaryocyte cell lines, polyploidization can be obtained by using cytochalasin B, an inhibitor of the actin polymerization. The Nucleolar Organizer Regions (AgNORs) are parts of nucleolar D...

journal_title：Anticancer research

authors： Baatout S,Chatelain B,Staquet P,Symann M,Chatelain C

更新日期：1998-01-01 00:00:00

abstract：:Variations in dietary exposure to several minerals may alter the risk of acquiring colorectal cancer. These minerals include selenium, zinc, calcium, sodium, potassium, iron and fluoride. The mechanism by which each of these minerals alters cancer risk is not established. However, as both the epidemiologic and experim...

journal_title：Anticancer research

authors： Nelson RL

更新日期：1987-05-01 00:00:00

abstract：:Thirty advanced breast cancer patients received Vinorelbine (VNB) according to two different schedules: a weekly i.v. bolus of 30 mg/m (14 patients) or a continuous infusion (CI) schedule comprising 8 mg i.v. bolus on day 1 followed by 8 mg/m2/die CI day 1 to 4, q 21 days (16 patients). 36% of patients had received at...

journal_title：Anticancer research

authors： Gasco M,Gardin G,Repetto L,Campora E,Rosso R

更新日期：1997-03-01 00:00:00

abstract：:Calcitriol (1,25-dihydroxyvitamin D3), the active form of vitamin D, promotes growth inhibition and differentiation in prostate cancer (PCa) cells. To unravel the molecular pathways of calcitriol actions, cDNA microarray analysis was used to identify novel calcitriol target genes including two that play key roles in t...

journal_title：Anticancer research

authors： Moreno J,Krishnan AV,Peehl DM,Feldman D

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Because treatment of advanced pancreatic cancer is often unsuccessful, early detection is important. Codon 12 c-Ki-ras mutations have been found in 80-90% of pancreatic cancer cases and are a potential early marker for pancreatic cancer, but obtaining tissue or fluid for analysis can be difficult. We therefo...

journal_title：Anticancer research

authors： Abbruzzese JL,Evans DB,Raijman I,Larry L,King T,Leach SD,Frazier ML

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND/AIM:Metastases involving the adrenal glands can be treated surgically or with radiation therapy. Retrospective studies indicate that radiotherapy for this indication is safe, well-tolerated and associated with symptom palliation and good local control. We conducted this analysis to report on patterns and out...

journal_title：Anticancer research

authors： Buergy D,Rabe L,Siebenlist K,Stieler F,Fleckenstein J,Giordano FA,Wenz F,Boda-Heggemann J

更新日期：2018-08-01 00:00:00

abstract：:Using gas chromatography, the fatty acid profile has been measured in subcutaneous fat obtained from women undergoing biopsy for benign and malignant breast conditions. There was a similar proportion of saturated and unsaturated fatty acids in both types or fat, suggesting that long-term differences in fatty acid cons...

journal_title：Anticancer research

authors： Caleffi M,Ashraf J,Rowe PH,Thomas BS,Fentiman IS

更新日期：1987-11-01 00:00:00

abstract：:Cancer is a family affair. Clinical work and research studies have shown that cancer affects the entire family and that spouses especially are often highly distressed. Breast cancer has a special importance for a couple. It is convenient to help the patient and her husband together. In the first six months especially ...

journal_title：Anticancer research

authors： Katz C,Bösch G,Herzog RE

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Biodegradable loaded systems are promising devices for controlled and sustained release of anticancer drugs to brain tumours. We investigated the influence of drug-release profiles of 5-fluorouracil-loaded microspheres designed for the treatment of malignant gliomas. MATERIALS AND METHODS:2.5 mg 5-FU delive...

journal_title：Anticancer research

authors： Roullin VG,Lemaire L,Venier-Julienne MC,Faisant N,Franconi F,Benoit JP

更新日期：2003-01-01 00:00:00

abstract：:Prophylactic cranial irradiation (PCI) is still an open question despite the fact that ten randomized trials have been published in the past, addressing its impact on overall survival, disease-free survival and incidence of brain recurrences. The majority of these trials allow us to conclude that PCI is only useful in...

journal_title：Anticancer research

authors： Vitale V,Scolaro T,Orsatti M

更新日期：1994-01-01 00:00:00

abstract：:Reduction of nitroblue tetrazolium by blood monocytes was significantly increased following post-operative radiation therapy for breast cancer. Attachment and ingestion of yeast particles by monocytes was not affected. Exposure of purified monocytes in vitro to 13 Gy did not significantly affect NBT reduction of yeas...

journal_title：Anticancer research

authors： Jarstrand C,Petrini B,Wasserman J,Blomgren H,Strender LE

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND/AIM:The presence of ascites in ovarian cancer patients is considered a negative prognostic factor. The underlying mechanisms are not clearly understood. MATERIALS AND METHODS:The amount of ascites was evaluated, preferably, using diffusion-weighted MRI at primary diagnosis in a retrospective cohort of 214 w...

journal_title：Anticancer research

authors： Coosemans AN,Baert T,D'Heygere V,Wouters R,DE Laet L,VAN Hoylandt A,Thirion G,Ceusters J,Laenen A,Vandecaveye V,Vergote I

更新日期：2019-11-01 00:00:00

abstract：UNLABELLED:The aim of the present study was to evaluate the effectiveness and safety of hepatic re-resection for breast cancer liver metastases. PATIENTS AND METHODS:Between January 2004 and December 2014 seven patients were submitted to liver re-resection for breast cancer liver metastases at our Center. The main inc...

journal_title：Anticancer research

authors： BacalbaȘa N,Balescu I,Dima S,Popescu I

更新日期：2015-12-01 00:00:00

abstract：:Since the discovery of cisplatin about 40 years ago, the design of innovative metal-based anticancer drugs is a growing area of research. Transition metal coordination complexes offer potential advantages over the more common organic-based drugs, including a wide range of coordination number and geometries, accessible...

journal_title：Anticancer research

authors： Pottier A,Borghi E,Levy L

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to compare the accuracy of 18-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) and thallium-201 (Tl-201) single photon emission computed tomography (SPECT) in differentiating recurrent/residual nasopharyngeal carcinomas (NPC) from post-radiotherapy (RT) changes in patients with ...

journal_title：Anticancer research

authors： Tsai MH,Huang WS,Tsai JJ,Chen YK,Changlai SP,Kao CH

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:The balance between cell proliferation and apoptosis plays a significant role in cancer development. The expressions of the p53 and c-myc genes, both strongly related to cell proliferation and apoptosis, were studied in sequential histological grades of oral carcinogenesis in an animal model. MATERIALS AND ...

journal_title：Anticancer research

authors： Papakosta V,Vairaktaris E,Vylliotis A,Derka S,Nkenke E,Vassiliou S,Lazaris A,Mourouzis C,Rallis G,Spyridonidou S,Anagnostopoulou S,Perrea D,Donta I,Yapijakis C,Patsouris E

更新日期：2006-07-01 00:00:00

abstract：:Phorbol ester, 12-0-Tetradecanoyl-13-Phorbol-Acetate (TPA), induces a terminal macrophage-like differentiation of cells from human acute myelogenous leukemia cell lines. We report here that blastoid cells obtained from acute nonlymphocytic leukemia (M1-M2) undergo differentiation-related changes characteristic of macr...

journal_title：Anticancer research

authors： Joshi KS,Rao SG,Joshi DS,Advani SH,Bhisey AN

更新日期：1988-11-01 00:00:00

abstract：:We report a case of secondary chondrosarcoma arising in the ilium showing spontaneous regression after frequent local tumor recurrences followed by multiple surgeries of marginal or intralesional excision. The patient was a 16-year-old boy who had been diagnosed as having multiple exostosis from 9 years of age. He exp...

journal_title：Anticancer research

authors： Nakamura S,Kusuzaki K,Murata H,Takeshita H,Hirata M,Hashiguchi S,Hirasawa Y

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND/AIM:The importance of hadron therapy in the cancer management is growing. We aimed to refine the biological effect detection using a vertebrate model. MATERIALS AND METHODS:Embryos at 24 and 72 h postfertilization were irradiated at the entrance plateau and the mid spread-out Bragg peak of a 150 MeV proton ...

journal_title：Anticancer research

authors： Brunner S,TŐkÉs T,SzabÓ ER,Polanek R,SzabÓ IZ,Reisz Z,GubÁn BK,SzijÁrtÓ AL,Brand M,Hans S,Karsch L,Lessmann E,Pawelke J,SchÜrer M,Beyreuther E,HideghÉty K

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:The number of patients with second malignancies is growing and they represent about one in six out of all new cancers. Second malignancies can be categorized into three major groups according to the predominant etiological factor(s): (i) treatment-related, (ii) part of a syndrome and (iii) those due to share...

journal_title：Anticancer research

authors： Mahmood S,Vu K,Tai P,Joseph K,Koul R,Dubey A,Yu E

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:The correlation between telomerase activity and antitumor effects was investigated in cell lines of human gastric (MKN-28, MKN-45, and MKN-74) and breast (T-47D, MCF-7, ZR75-1) cancers to evaluate the possibility of utilizing this enzyme to predict tumor response to chemotherapy. MATERIALS AND METHODS:After...

journal_title：Anticancer research

authors： Terashima M,Takiyama I,Uesugi N,Sasaki N,Takagane A,Hayakawa Y,Abe K,Araya M,Nishizuka S,Shimooki O,Nakaya T,Irinoda T,Yonezawa H,Oyama K,Saito K

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:Bone metastases or local recurrences are widely viewed as poor prognostic signs for successful immunotherapy for metastatic renal cell carcinoma (RCC), and even partial remission is a rarity. We assessed the efficacy of the combination of radio and chemo-immunotherapy for bone metastases or local recurrences fo...

journal_title：Anticancer research

authors： Brinkmann OA,Bruns F,Prott FJ,Hertle L

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Postoperative pancreatic fistula (POPF) remains a major complication after pancreaticoduodenectomy (PD), and the prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) after PD is poor. PATIENTS AND METHODS:A multi-institutional retrospective study was performed in 174 patients who underwent PD ...

journal_title：Anticancer research

authors： Yamashita Y,Yoshizumi T,Fukuzawa K,Nishizaki T,Tsujita E,Kajiyama K,Soejima Y,Yamagata M,Yamamoto K,Adachi E,Sugimachi K,Ikeda Y,Uchiyama H,Maeda T,Itoh S,Harimoto N,Ikegami T,Maehara Y

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:It was recently reported that expression of prospero homeobox protein-1 (PROX1) is correlated with the prognosis of esophageal cancer and colorectal cancer. However, its correlation with gastric cancer is unclear. MATERIALS AND METHODS:Our study analyzed the effect of PROX1 knockdown on the migration, invas...

journal_title：Anticancer research

authors： Ueta K,Otowa Y,Kakeji Y,Hirashima M

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND/AIM:Stage-specific embryonic antigen-4 (SSEA-4) expression is associated with malignant aggressiveness and is useful as a marker for identifying cancer stem cells. Our aim was to assess the relationship between hormonal therapy and SSEA-4 expression in prostate cancer (PC). MATERIALS AND METHODS:SSEA-4 expr...

journal_title：Anticancer research

authors： Yuno T,Miyata Y,Matsuo T,Mukae Y,Otsubo A,Mistunari K,Ohba K,Suda T,Saito S,Sakai H

更新日期：2020-10-01 00:00:00

abstract：:Immunocytochemical assays were performed on frozen sections of inflammatory breast carcinomas (n = 22) using the following monoclonal antibodies (MoAb): anti-pHER2/neu, cathepsin, pS2, ER, PR and MoAb Ki67. The distribution of these proteins, known as prognostic indicators, was evaluated with an image analysis system ...

journal_title：Anticancer research

authors： Charpin C,Bonnier P,Khouzami A,Vacheret H,Andrac L,Lavaut MN,Allasia C,Piana L

更新日期：1992-05-01 00:00:00