Health-related quality of life and alternative forms of exercise in Parkinson disease.

abstract：INTRODUCTION:Blood uric acid represents an important biomarker in sporadic Parkinson's disease (PD). Whether uric acid levels change in genetic forms of PD is beginning to be assessed. The aim of the present study was to evaluate differences in serum uric acid level among PD patients harboring mutations in the glucocer...

journal_title：Parkinsonism & related disorders

authors： Koros C,Simitsi AM,Papagiannakis N,Bougea A,Prentakis A,Papadimitriou D,Pachi I,Antonelou R,Angelopoulou E,Beratis I,Bozi M,Papageorgiou SG,Trapali XG,Stamelou M,Stefanis L

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:No effective treatment for tardive dystonia (TD) has been well established. Deep brain stimulation (DBS) can ameliorate motor manifestations in primary dystonia, and may also be an effective approach for TD. OBJECTIVES:This study aimed to illuminate the long-term efficacy and safety of subthalamic nucleus (...

journal_title：Parkinsonism & related disorders

authors： Deng ZD,Li DY,Zhang CC,Pan YX,Zhang J,Jin H,Zeljec K,Zhan SK,Sun BM

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Punctual delivery of dopaminergic medication to Parkinson's disease (PD) patients may be important in optimizing disease control. We tested the hypothesis that prompt delivery of l-dopa medications to emergency hospital inpatients was associated with a decreased length of stay in hospital. METHODS:The study...

journal_title：Parkinsonism & related disorders

authors： Skelly R,Brown L,Fogarty A

更新日期：2017-02-01 00:00:00

abstract：:Although attentional impairments (particularly cognitive slowing) are frequent in Parkinson's disease (PD), the mechanisms underlying these phenomena have not been fully characterized. The MRI-compatible version of the Symbol Digit Modalities Test (SDMT) has been applied to healthy individuals but not previously to pa...

journal_title：Parkinsonism & related disorders

authors： Grolez G,Viard R,Lopes R,Kuchcinski G,Defebvre L,Devos D,Dujardin K,Moreau C

更新日期：2020-07-01 00:00:00

abstract：:Primary monogenic forms of dystonia manifest solely or mainly with dystonia; they have been linked to a number of genes and loci and assigned "DYT" numbers. The pure dystonia syndrome early-onset primary dystonia (DYT1) manifests with dominantly-inherited generalized dystonia, often with focal onset in a limb. DYT1 is...

journal_title：Parkinsonism & related disorders

authors： Spatola M,Wider C

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of solifenacin succinate in Parkinson's disease (PD) patients suffering from overactive bladder (OAB). BACKGROUND:Urinary dysfunction is a commonly encountered non-motor feature in PD that significantly impacts patient quality of life. DESIGN/METHODS:This was a double-blind, randomi...

journal_title：Parkinsonism & related disorders

authors： Zesiewicz TA,Evatt M,Vaughan CP,Jahan I,Singer C,Ordorica R,Salemi JL,Shaw JD,Sullivan KL,Non-Motor Working Group of the Parkinson Study Group (PSG).

更新日期：2015-05-01 00:00:00

abstract：:Sex-linked dystonia parkinsonism (XDP) was reported by Lee et al. in 1975 occurring endemically in Panay, Philippines. It is an adult onset, sex-linked, predominantly male, severe, progressive movement disorder with high penetrance and a high frequency of generalization. The movement disorder is characterized by dysto...

journal_title：Parkinsonism & related disorders

authors： Lee LV,Maranon E,Demaisip C,Peralta O,Borres-Icasiano R,Arancillo J,Rivera C,Munoz E,Tan K,Reyes MT

更新日期：2002-10-01 00:00:00

abstract：:Synchronization of neuronal activity within and across distributed brain regions is a fundamental property of cortical and subcortical networks and serves a variety of functions including motor and cognitive processes. Data will be reviewed here from cross-sectional EEG and MEG studies to suggest that Parkinson's dise...

journal_title：Parkinsonism & related disorders

authors： Berendse HW,Stam CJ

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Patients with Parkinson's disease (PD) frequently lose weight, even in the early stages of the disease. Our objective was to clarify the association between low body mass index (BMI) and life prognosis in PD. METHODS:We conducted a retrospective cohort study of 651 PD patients (380 females), with a primar...

journal_title：Parkinsonism & related disorders

authors： Park K,Oeda T,Kohsaka M,Tomita S,Umemura A,Sawada H

更新日期：2018-10-01 00:00:00

abstract：:Moclobemide, a potent reversible monoamine-oxidase A (MAO-A) inhibitor, is an effective antidepressant that does not cause impairment of cognitive function in elderly patients and might be beneficial to motor deficits in Parkinson's disease (PD). In a 12-week open-label prospective study, we administered moclobemide (...

journal_title：Parkinsonism & related disorders

authors： Giménez-Roldán S,Dobato JL,Mateo D

更新日期：1997-12-01 00:00:00

abstract：:The immunohistochemical demonstration of reactive microglia and activated complement components suggests that chronic inflammation occurs in affected brain regions in Parkinson's disease (PD). Evidence from humans and monkeys exposed to MPTP indicates this inflammation may persist many years after the initial stimulus...

journal_title：Parkinsonism & related disorders

authors： McGeer PL,McGeer EG

更新日期：2004-05-01 00:00:00

abstract：:A prevalence survey of movement disorders, epilepsy, hypertension and smoking was undertaken in Vejer de la Frontera, Southern Spain in 1988. A validated screening instrument designed for door-to-door tracing of specific disorders was used. Neurological diagnoses were based on: (1) direct anamnesis and examination by ...

journal_title：Parkinsonism & related disorders

authors： Acosta-Varo J,De Pedro-Cuesta J

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Motor complications may become major challenges in the management of patients with Parkinson's disease. In this study, we sought to determine the incidence, risk factors, evolution, and treatment of motor fluctuations and dyskinesias in a population-representative, incident Parkinson's disease cohort. METHO...

journal_title：Parkinsonism & related disorders

authors： Bjornestad A,Forsaa EB,Pedersen KF,Tysnes OB,Larsen JP,Alves G

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:Type 2 diabetes (T2DM) may increase the risk of Parkinson's disease (PD). We evaluated the role of oral anti-hyperglycemic agents (OAA) in any diabetes-PD linkage. METHODS:From the Taiwan National Health Insurance database on 01-01-2000, a representative cohort of 800,000 was obtained between 1996-01-01 and...

journal_title：Parkinsonism & related disorders

authors： Wahlqvist ML,Lee MS,Hsu CC,Chuang SY,Lee JT,Tsai HN

更新日期：2012-07-01 00:00:00

abstract：:The objective of this review is to assess the effectiveness of tai chi as a treatment option for Parkinson's disease (PD). We have searched the literature using 21 databases from their inceptions to January 2008, without language restrictions. We included all types of clinical studies regardless of their design. Their...

journal_title：Parkinsonism & related disorders

authors： Lee MS,Lam P,Ernst E

更新日期：2008-12-01 00:00:00

abstract：:We describe a 30-year-old woman who suffered from an unusual task-specific focal hand dystonia, which dominantly occurred with use of a spoon; there were no other activities affected, except for mild writer's dystonia on same side. This is the first report of a spoon-related focal dystonia. ...

journal_title：Parkinsonism & related disorders

authors： Song IU,Kim JS,Kim HT,Lee KS

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Non-motor symptom (NMS) differences between male Parkinson's disease (PD) and female PD, and between early-onset PD (EOPD) and late-onset PD (LOPD) in Chinese populations remain largely unknown. METHODS:A total of 522 PD patients from Southwest China were included. Patients were assessed using the Non-Motor...

journal_title：Parkinsonism & related disorders

authors： Guo X,Song W,Chen K,Chen X,Zheng Z,Cao B,Huang R,Zhao B,Wu Y,Shang HF

更新日期：2013-11-01 00:00:00

abstract：:This preliminary study aimed to analyse the roll-off of the foot during gait before and after implantation of a unilateral pallidal electrode in severely affected patients with Parkinson's disease (PD). Five subjects were tested in a gait laboratory during the "on" phase of the medication cycle. Spatiotemporal variabl...

journal_title：Parkinsonism & related disorders

authors： Nieuwboer A,De Weerdt W,Dom R,Nuttin B,Peeraer L,Pattyn A

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:X-linked dystonia-parkinsonism (XDP) is characterized by the unique transition of dystonia to parkinsonism and striatal degeneration. Slowing of saccades on clinical examination has been taken as suggestive of a progressive supranuclear palsy (PSP) phenotype. OBJECTIVES:To elucidate whether eye movement abn...

journal_title：Parkinsonism & related disorders

authors： Sprenger A,Hanssen H,Hagedorn I,Prasuhn J,Rosales RL,Jamora RDG,Diesta CC,Domingo A,Klein C,Brüggemann N,Helmchen C

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Parkinson's disease is characterized by pathological α-synuclein accumulation and cell death, which has been hypothesized to originate in peripheral nerve terminals and subsequently spread via autonomic nerves. Supporting this, most Parkinson's disease patients experience autonomic non-motor symptoms such as...

journal_title：Parkinsonism & related disorders

authors： Knudsen K,Fedorova TD,Hansen AK,Sommerauer M,Haase AM,Svendsen KB,Otto M,Østergaard K,Krogh K,Borghammer P

更新日期：2019-01-01 00:00:00

abstract：:Several changes to society in the last four decades have had implications for people and their families living with Parkinson's disease (PD): (1) The change in the role of voluntary organisations highlighting the importance of listening to the needs of the patients and their families. (2) Demographic changes resulting...

journal_title：Parkinsonism & related disorders

authors： Baker MG

更新日期：2007-01-01 00:00:00

abstract：:The 'hung-up' knee jerk (HUKJ) is a specific, although rarely appreciated, clinical sign of Huntington's Disease. A HUKJ was present in 11 of 31 consecutive patients with Huntington's Disease seen in our practice. The clinical characteristics of these patients are described and an EMG recording of the HUKJ is presente...

journal_title：Parkinsonism & related disorders

authors： Brannan T

更新日期：2003-06-01 00:00:00

abstract：:Although the subspeciality of movement disorders was established in neurology more than 20 years ago, it is relatively new in Thailand, and while most physicians are generally aware of Parkinson's disease, they often are not familiar with dystonia. As one of the common movement disorders seen in general practice, a nu...

journal_title：Parkinsonism & related disorders

authors： Bhidayasiri R,Kaewwilai L,Wannachai N,Brenden N,Truong DD,Devahastin R

更新日期：2011-11-01 00:00:00

abstract：:Parkinson's disease (PD) patients have a ninefold increased risk of recurring falls compared to healthy controls. The risk of falling due to cardiovascular dysautonomia (CVD) is not quantifiable. But, CVD is an integral part of the disease and at least 20% of PD patients suffer from orthostatic hypotension, an express...

journal_title：Parkinsonism & related disorders

authors： Martignoni E,Tassorelli C,Nappi G

更新日期：2006-05-01 00:00:00

abstract：:An international panel of movement disorders specialists explored the views and perceptions of people with Parkinson's disease (PD) about their condition and its treatment, including the potential mismatch between the clinician's view of the patient's condition and their own view of what aspects of the disease most af...

journal_title：Parkinsonism & related disorders

authors： Bhidayasiri R,Panyakaew P,Trenkwalder C,Jeon B,Hattori N,Jagota P,Wu YR,Moro E,Lim SY,Shang H,Rosales R,Lee JY,Thit WM,Tan EK,Lim TT,Tran NT,Binh NT,Phoumindr A,Boonmongkol T,Phokaewvarangkul O,Thongchuam Y,Vora

更新日期：2020-03-01 00:00:00

abstract：:Hereditary spastic paraplegia with thin corpus callosum is a rare degenerative disease, which is characterized by a progressive weakness of the lower limbs with a hypoplastic corpus callosum, and is often associated with other symptoms such as mental impairment, amyotrophy, sensory disturbances, dysuria, nystagmus and...

journal_title：Parkinsonism & related disorders

authors： Kang SY,Lee MH,Lee SK,Sohn YH

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The freezing phenomenon is among the most disabling symptoms of Parkinson's disease (PD) manifesting most commonly as Freezing of Gait with a paroxysmal cessation of effective stepping. Recent studies have suggested that freezing is related to both impairments in conflict resolution as well as the processing...

journal_title：Parkinsonism & related disorders

authors： Matar E,Shine JM,Naismith SL,Lewis SJ

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To examine the tolerability and effectiveness of propranolol in treating tardive dyskinesia (TD). BACKGROUND:TD is a disabling, often irreversible, movement disorder that results from chronic therapy with dopamine receptor blocking drugs. There are no treatments currently approved for this disorder. Proprano...

journal_title：Parkinsonism & related disorders

authors： Hatcher-Martin JM,Armstrong KA,Scorr LM,Factor SA

更新日期：2016-11-01 00:00:00

abstract：INTRODUCTION:There is currently no definitive diagnostic test for Parkinson's disease (PD) and the current diagnostic procedure primarily relies on clinical manifestations. A hypointense appearance of nigrosome-1 (or absence of the "swallow tail" sign) on magnetic resonance imaging (MRI) has been proposed as a biomarke...

journal_title：Parkinsonism & related disorders

authors： Chau MT,Todd G,Wilcox R,Agzarian M,Bezak E

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Tremor-related quality of life is a multi-dimensional concept that reflects the physical, emotional and other health effects of tremor. Curiously, tremor-related quality of life has never been directly compared in patients with the two major tremor disorders, essential tremor (ET) and Parkinson's disease (PD...

journal_title：Parkinsonism & related disorders

authors： Louis ED,Machado DG

更新日期：2015-07-01 00:00:00